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Natural medicinal composition, its preparation method and application

A technology of natural medicine and composition, applied in the direction of drug combination, pharmaceutical formula, antineoplastic drugs, etc.

Inactive Publication Date: 2013-10-23
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, and at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural medicinal composition, its preparation method and application

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Effect test

Embodiment approach

[0031] The first step: preparation of various extracts

[0032] (1) Preparation of cinnamon gallnut decoction concentrated extract

[0033] According to the compatibility ratio of 1-5:1, take cinnamon and gallnut, soak in distilled water, heat and decoct, filter, add distilled water to the medicinal residue, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and use an ultrafiltration membrane Filter, dry under reduced pressure, that is.

[0034] (2) Preparation of cinnamaldehyde

[0035] Grind cinnamon, weigh cinnamon bark powder, heat and extract with 95% ethanol in a Soxhlet extractor, filter, recover ethanol under reduced pressure, conduct steam distillation, add NaCl to the distillate, extract with diethyl ether three times, combine diethyl ether Add an appropriate amount of anhydrous calcium chloride desiccant to the extract, dry it for 30 minutes, remove the desiccant, recover ether, and then use vacuum distillation to collect fract...

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Abstract

The invention relates to a natural medicinal composition, its preparation method and application. The natural medicinal composition consists of a cinnamon gallnut decocted concentrated extract, cinnamaldehyde and a gallnut acetone extract in a ratio of 4-7:3-4:5-9. The composition provided in the invention has excellent efficacy on cancer chemotherapy related diarrhea and simultaneously has a synergistic effect on cancer chemotherapy..

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of cinnamon gallnut decoction concentrated extract, cinnamaldehyde and gallnut acetone extract, the preparation method of the natural medicine composition and the natural medicine composition Use of the pharmaceutical composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhea. I...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P35/00A61P1/12A61K35/64A61K31/11
Inventor 石强
Owner 石强