Preparation method of magnesium phosphate medical bone adhesive

A technology of bone cement and magnesium phosphate, applied in chemical instruments and methods, applications, medical science and other directions, can solve the problem of low bonding strength of magnesium phosphate medical bone cement, and achieve controllable curing time and mechanical properties. Good, low exothermic effect
CN103407980AInactive Publication Date: 2013-11-27XIAN UNIV OF TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
XIAN UNIV OF TECH
Publication Date
2013-11-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

A preparation method of a magnesium phosphate medical bone adhesive concretely comprises the following steps: 1, calcining medical MgO, and carrying out dry grinding to obtain powder having a granularity of 0-20mum; 2, placing KH2PO4 in a drying box, drying at 120DEG C for above 24h, and carrying out dry grinding to obtain powder having a granularity of 0-20mum; 3, processing an additive to prepare a dilute solution having a concentration of 1.0-10.0%, and uniformly stirring to obtain a solid phase mixed solution A; and 4, uniformly mixing the MgO powder obtained in step 1 with the KH2PO4 powder obtained in step 2 to obtain a mixture B, adding the mixture B to the solid phase mixed solution A while stirring to obtain a slurry C, and continuously stirring the slurry C for 1min to obtain the magnesium phosphate medical bone adhesive. The preparation which allows the additive to be added into the solid phase mixed solution obviously improves the adhesive strength of the prepared magnesium phosphate medical bone adhesive.
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Description

technical field

[0001] The invention belongs to the technical field of adhesive preparation, and relates to a preparation method of magnesium phosphate medical bone adhesive. Background technique

[0002] In the clinical treatment of severe comminuted fractures, it is often difficult to use mechanical fixation due to the small bone fragments, which has become one of the problems that plague medical workers. Metal materials and physically bonded ceramic materials have become traditional bone substitute materials due to their excellent mechanical properties, but metal materials have poor biological activity, and will cause metal ions to dissolve under long-term action of body fluids, resulting in cell toxicity; while traditional ceramic materials are highly brittle , Difficult to process, need pre-sintered molding, difficult to match the shape of the bone defect, so these materials are likely to cause problems such as stress shielding, foreign body rejection and non-biodegrada...

Claims

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