Tetrandrine drug and its preparation for increasing white blood cells and treating aplastic anemia

Abstract

The invention relates to new applications of isotetrandrine in pharmaceutical field. Applications of isotetrandrine in preparation of a medicine used for treating low leukocyte and aplastic anemia are disclosed for the first time. The isotetrandrine medicine is high in activity, excellent in drug effect, fast in leukocyte increasing, low in dosage, and high in purity. Compared with existing technologies, the isotetrandrine medicine is a novel medicine used for increasing leukocyte and treating aplastic anemia with safety, efficiency and controllable quality; is worth clinical popularization and application; and possesses high social values and economic values.

Description

technical field [0001] The invention relates to a new use of a compound tetrandrine in the field of pharmacy, which is clinically used for treating leukopenia and aplastic anemia, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Leukopenia and agranulocytosis are common and frequently-occurring diseases of the blood system in internal medicine. The causes may be caused by drugs, infections and diseases, and some of them are unknown. At present, malignant tumors have become an important factor that threatens human health, and radiotherapy and chemotherapy are one of the main means of tumor treatment. However, due to the lack of specificity, it will destroy normal cells while killing tumor cells, especially for bone marrow with vigorous proliferation. The damage to the system is relatively serious; in addition, some metabolites of the tumor itself also damage the bone marrow. Chemotherapy eventually inhibits the hematopoietic fu...

AI Technical Summary

Problems solved by technology

At present, malignant tumors have become an important factor that threatens human health, and radiotherapy and chemotherapy are one of the main means of tumor treatment. However, due to the lack of specificity, it will destroy normal cells while killing tumor cells, especially for bone marrow with vigorous proliferation. The damage to the system is relatively serious; in addition, some metabolites of the tumor itself also damage the bone marrow. Chemotherapy eventually inhibits the hematopoietic function of the bone marrow, causes peripheral leukopenia, and further causes low immune function of the body, causing secondary infection and other adverse reactions, resulting in many tumors. Patients are forced to reduce or discontinue chemotherapy, leading to treatment failure

Although there are drugs for the treatment of damage to the bone marrow hematopoietic system, such as colony-stimulating factor, the application range is limited due to the high price.

However, traditional Chinese medicines for invigorating the spleen, nourishing the kidney, and nourishing qi and promoting blood are restrained from their large-scale clinical application due to unclear ingredients, slow effects, and unclear mechanism of action.

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