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Method for detecting content of dioxane in children cosmetics

A technology of dioxane and cosmetics, applied in the field of detection of harmful substances in cosmetics, to achieve the effect of lowering the detection limit, enhancing the SERS signal, and being easy to popularize and apply

Active Publication Date: 2014-04-09
FROG PRINCE (FUJIAN) BABY & CHILD CARE PROD CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, in the prior art, there is no report on the use of surface-enhanced Raman spectroscopy to detect the content of dioxane in cosmetics

Method used

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  • Method for detecting content of dioxane in children cosmetics
  • Method for detecting content of dioxane in children cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A method for detecting the content of dioxane in children's cosmetics is carried out according to the following steps:

[0026] (1) Pretreat the sample to be tested to form a sample solution. The pretreatment of the sample to be tested can be processed by common methods, such as one or more of dissolution, extraction, micro-extraction, distillation and chromatography. Specifically, it can be carried out as follows: first, weigh 20 g of the sample to be tested, and accurately to 0.0001g; then pour the sample to be tested into a beaker filled with 100ml of ethanol, soak for 10h, then stir for 3h; finally, filter with suction, concentrate the filtrate to 5ml, and seal it for later use.

[0027] (2) Stir 20ml of an aqueous solution containing 1mM silver nitrate, 0.25mM sodium dodecylsulfonate and 1mM ethylenediaminetetraacetic acid in the container, and adjust the pH value of the aqueous solution to 11; then, add 50μL of 0 .1mol / L ascorbic acid solution, keep stirring for ...

Embodiment 2

[0036]A method for detecting the content of dioxane in children's cosmetics is carried out according to the following steps:

[0037] (1) Pretreat the sample to be tested to form a sample solution. The pretreatment of the sample to be tested can be processed by common methods, such as one or more of dissolution, extraction, micro-extraction, distillation and chromatography. Specifically, it can be carried out as follows: first, weigh 20 g of the sample to be tested, and accurately to 0.0001g; then pour the sample to be tested into a beaker filled with 100ml of ethanol, soak for 12h, then stir for 4h; finally, filter with suction, concentrate the filtrate to 5ml, and seal it for later use.

[0038] (2) Add 20ml of aqueous solution into the container and stir, the aqueous solution contains 1.2mM silver nitrate, 0.5mM sodium dodecylsulfonate and 0.8mM ethylenediaminetetraacetic acid, and adjust the pH value of the aqueous solution to 10; then, Add 50 μL of 0.5 mol / L ascorbic aci...

Embodiment 3

[0047] A method for detecting the content of dioxane in children's cosmetics is carried out according to the following steps:

[0048] (1) Pretreat the sample to be tested to form a sample solution. The pretreatment of the sample to be tested can be processed by common methods, such as one or more of dissolution, extraction, micro-extraction, distillation and chromatography. Specifically, it can be carried out as follows: first, weigh 20 g of the sample to be tested, and accurately to 0.0001g; then pour the sample to be tested into a beaker filled with 100ml of ethanol, soak for 18h, then stir for 5h; finally, filter with suction, concentrate the filtrate to 5ml, and seal it for later use.

[0049] (2) Add 20ml of aqueous solution into the container and stir, the aqueous solution contains 0.8mM silver nitrate, 1mM sodium dodecylsulfonate and 2mM ethylenediaminetetraacetic acid, and adjust the pH value of the aqueous solution to 10.5; then, add 50μL of 1mol / L ascorbic acid so...

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Abstract

The invention relates to a method for detecting the content of dioxane in children cosmetics. The method comprises the following steps: (1) pretreating a sample to be detected so as to form a sample solution; (2) uniformly mixing the sample solution with prepared nanometer silver colloid so as to form a sample mixed solution; (3) dropping the sample mixed solution on a substrate, and naturally airing, thus obtaining a detection sample; (4) detecting the detection sample by adopting surface-enhanced Raman scattering, thus obtaining an SERS (surface enhanced Raman spectrum) spectrogram of the detection sample; and (5) comparing the obtained SERS spectrogram of the detection sample with an SERS spectrogram of a dioxane standard solution, and calculating so as to obtain the content of the dioxane in the detection sample. The method is simple, convenient and fast to operate and can be used for rapidly carrying out qualitative and quantitative analysis on the content of the dioxane in children cosmetics.

Description

technical field [0001] The invention belongs to the technical field of detection of harmful substances in cosmetics, and in particular relates to a method for detecting dioxane content in children's cosmetics. Background technique [0002] Dioxane, alias dioxane, 1,4-dioxane, colorless transparent liquid, molecular formula is C 4 h 8 o 2 , with a molecular weight of 88.1 and a slight fragrance. Dioxane is slightly toxic and is a prohibited substance in cosmetics. It can enter the body through inhalation, ingestion and percutaneous absorption. It has anesthesia and irritation to the skin, eyes and respiratory system, and has accumulation in the body. Dioxane is not a raw material for production, but a by-product of the production of fatty alcohol polyoxyethylene ether sulfate (AES). It is mainly used as a solvent, emulsifier, detergent, etc. It has a strong affinity for water in the natural environment, and It is not easy to be degraded by organisms, and it has obvious ca...

Claims

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Application Information

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IPC IPC(8): G01N21/65
Inventor 曾念泽陈敏华胡建强陈宇宇张念椿卢剑陈来成
Owner FROG PRINCE (FUJIAN) BABY & CHILD CARE PROD CO LTD
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