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New application of pharmaceutical composition in prevention or treatment of osteoporosis

A composition and new application technology, applied in the field of new application of pharmaceutical composition in the prevention or treatment of osteoporosis, capable of solving problems such as increased bone fragility, abnormal endometrium hyperplasia, and osteomalacia

Inactive Publication Date: 2014-04-16
庞会心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For osteoporosis, at present, drugs such as estrogen, calcium, active vitamin D, calcitonin and fluoride are most used in clinical treatment of this disease. Ubiquitous, such as long-term use of synthetic estrogen drugs can lead to abnormal hyperplasia of the breast and endometrium, continuous use of bisphosphonates can reduce bone turnover rate and increase bone fragility, and fluoride alone can cause osteomalacia , allergies to vitamin D and calcitonin

Method used

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  • New application of pharmaceutical composition in prevention or treatment of osteoporosis
  • New application of pharmaceutical composition in prevention or treatment of osteoporosis
  • New application of pharmaceutical composition in prevention or treatment of osteoporosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0065] Weigh 110g of glucosamine hydrochloride, 151.5g of biological calcium carbonate, 30g of Rhizoma Drynariae extract, 4.5g of casein phosphopeptide, 70g of chondroitin sulfate, and 30g of Epimedium extract for bacterial inspection, pass through a 80-mesh sieve, and mix Evenly, add 5.5g magnesium stearate again; Fill capsules with the mixture that obtains with automatic capsule machine, make the health product of preventing or treating osteoporosis, every capsule content is 400mg, makes 1000 altogether;

Embodiment 2

[0067] Weigh 90g of glucosamine hydrochloride, 161.5g of biological calcium carbonate, 40g of drynaria extract, 4.5g of casein phosphopeptide, 60g of chondroitin sulfate, 40g of epimedium extract, 32.5g of starch, 20g of microcrystalline cellulose Bacterial inspection respectively, passed through 80 mesh sieve, mixed evenly; granulated with 60%-80% ethanol, dried, added 1.5g magnesium stearate, mixed evenly, compressed into 1000 tablets of health care products for prevention or treatment of osteoporosis .

Embodiment 3

[0069] Weigh 120g of glucosamine hydrochloride, 190g of biological calcium carbonate, 72g of Rhizoma Drynariae extract, 8g of casein phosphopeptide, 90g of chondroitin sulfate, 120g of Epimedium extract, 30g of sucrose, and 20g of dextrin for bacterial inspection respectively. 80-mesh sieve, mixed evenly; granulated with absolute ethanol, dried, granulated, and packed separately. Make 1000 bags of medicines for preventing or treating osteoporosis.

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Abstract

The invention provides new application of a pharmaceutical composition. The pharmaceutical composition is composed of the following components in percentage by weight: 15-35% of glucosamine hydrochloride, 20-40% of biological calcium carbonate, 5-20% of rhizoma drynariae extracts, 1-5% of casein phosphopeptides, 10-20% of chondroitin sulfate, and 10-30% of epimedium extracts. The new application is that the pharmaceutical composition is used for preparing drugs or health-care products for preventing or treating osteoporosis.

Description

technical field [0001] The invention relates to a new application of a medicine, in particular to a new application of a pharmaceutical composition in the preparation of medicines for preventing or treating osteoporosis. Background technique [0002] With the aging of the social population, osteoporosis has become the most common metabolic bone disease, and its serious consequences are osteoporotic fractures (common bone parts include wrist and ankle, hip and vertebral body) etc.) and various complications and sequelae caused by fractures. At present, the elderly in our country still mainly provide for the elderly at home. The frequent occurrence of osteoporosis not only seriously affects the quality of life of middle-aged and elderly people, but also brings relatively large economic pressure to the family and society. [0003] Modern medicine believes that osteoporosis is a systemic metabolic bone disease characterized by decreased bone mass and destruction of bone microst...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/17A23L1/29A61P19/10A61K36/296A61K31/7008A23L33/00
Inventor 庞会心
Owner 庞会心
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