Intestinal mucosa-improving selenium supplement and its preparation method and use

A technology for intestinal mucosa and selenium supplementation, applied in applications, animal feed, animal feed, etc., can solve the problems of narrow safety limit of selenium, low bioavailability, strong toxicity of sodium selenite, etc., achieve a large safety range and enhance immunity Effect, good effect of enhancing immune function

Inactive Publication Date: 2015-09-30
ZHEJIANG UNIV
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, sodium selenite is widely used as a selenium source in livestock and poultry diets, but sodium selenite has strong toxicity and low bioavailability, and the safety limit of selenium between the optimal concentration and the toxic concentration is very narrow

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Intestinal mucosa-improving selenium supplement and its preparation method and use
  • Intestinal mucosa-improving selenium supplement and its preparation method and use
  • Intestinal mucosa-improving selenium supplement and its preparation method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Embodiment 1, a kind of preparation method of intestinal mucosa improving type selenium supplement, carry out following steps successively:

[0049] 1) Grind the montmorillonite to 60 mesh, add water and stir evenly to make a montmorillonite suspension slurry with a mass concentration of 2%;

[0050] 2) Chitosan selenium was crushed to 40 mesh to obtain chitosan selenium powder;

[0051] 3) Add chitosan selenium powder to the montmorillonite suspension slurry obtained in step 1) and mix, adjust the pH to 2 with glacial acetic acid, and react at 40°C for 5 hours;

[0052] The weight ratio of the chitosan selenium powder and the montmorillonite in the montmorillonite suspension slurry is 1:3;

[0053] 4), wash the reaction mixture obtained in step 3) with water 4 times (wash with double distilled water until the pH of the washing liquid after washing is neutral), filter with suction, and dry at low temperature (dry at 60°C for 10 hours, thereby Make the water content ≤ ...

Embodiment 2

[0060] Embodiment 2, a preparation method of an intestinal mucosa-improving selenium supplement, the following steps are carried out in sequence:

[0061] 1) Grind the montmorillonite to 80 mesh, add water and stir evenly to make a suspension slurry of montmorillonite with a mass concentration of 5%;

[0062] 2) Chitosan selenium was pulverized to 50 mesh by conventional pulverization method to obtain chitosan selenium powder;

[0063] 3) Add chitosan selenium powder to the montmorillonite suspension slurry obtained in step 1) and mix, adjust the pH to 3 with glacial acetic acid, and react at 60°C for 6 hours;

[0064] The weight ratio of the chitosan selenium powder and the montmorillonite in the montmorillonite suspension slurry is 1:5;

[0065] 4) The reaction mixture obtained in step 3) was washed with water, suction filtered, dried at low temperature (at 60°C for 10 hours), and crushed to 200 mesh to obtain an intestinal mucosa-improving selenium supplement.

[0066] Th...

Embodiment 3

[0071] Embodiment 3, a preparation method of intestinal mucosa-improving selenium supplement, the following steps are carried out in sequence:

[0072] 1) Grind the montmorillonite to 80 mesh, add water and stir evenly to make a suspension slurry of montmorillonite with a mass concentration of 8%;

[0073] 2) Chitosan selenium was pulverized to 60 mesh by conventional pulverization method to obtain chitosan selenium powder;

[0074] 3) Add chitosan selenium powder to the montmorillonite suspension slurry obtained in step 1) and mix, adjust the pH to 3 with glacial acetic acid, and react at 60°C for 8 hours;

[0075] The weight ratio of the chitosan selenium powder and the montmorillonite in the montmorillonite suspension slurry is 1:5;

[0076] 4) Wash the mixed solution obtained in step 3) with water for 5 times, filter it with suction, dry it, and crush it to 300 mesh to obtain an intestinal mucosa-improving selenium supplement.

[0077] The selenium content of the intesti...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses an intestinal mucosa improving type selenium supplement, which is formed by chitosan selenium and montmorillonite through mixing according to the mass ratio of 1: (3-7). The invention further discloses a preparation method of the intestinal mucosa improving type selenium supplement, wherein the preparation method comprises the following steps: adding chitosan selenium powder into the montmorillonite suspension liquid (the mass concentration is 2-8%), mixing, adjusting the pH (potential of hydrogen) value to be 2-3.5 with glacial acetic acid, then reacting for 5-8h at 40-80 DEG C, wherein the mass ratio of the chitosan selenium powder and the montmorillonite in the montmorillonite suspension liquid is 1: (3-7); washing the obtained reactant mixture solution with water, filtering, drying at low temperature, and crushing to be 100-300Mu, so as to obtain the intestinal mucosa improving type selenium supplement. The intestinal mucosa improving type selenium supplement is used as a feed additive for beasts and birds or animals, the feed additive has both effect of supplementing selenium and function of enhancing immunity.

Description

technical field [0001] The invention relates to an intestinal mucosa-improving selenium supplement, a preparation method and application. Background technique [0002] Selenium is one of the seven essential trace elements in animal feed and one of the fourteen essential trace elements for humans. The function of selenium is multifaceted, and it has a wide range of biological activities such as tumor suppressor, anti-virus, anti-oxidation and immune regulation. [0003] At present, sodium selenite is widely used as a selenium source in livestock and poultry diets, but sodium selenite has strong toxicity and low bioavailability, and the safety limit of selenium between the optimal concentration and the toxic concentration is very narrow. Appropriate amount of selenium is helpful to the health of animals, while excessive selenium can easily lead to poisoning of humans and animals. [0004] In recent years, people have gradually turned their attention to organic selenium, whic...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/16
Inventor 韩新燕钊守梅马原菲吴志鹏吕梦园
Owner ZHEJIANG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap