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Traditional Chinese medicinal composition for treating dysmenorrhea and preparation method thereof

A composition and technology of traditional Chinese medicine are applied in the field of traditional Chinese medicine composition for treating primary dysmenorrhea and the field of preparation thereof, which can solve the problems of inability to satisfy patients and the like

Active Publication Date: 2014-05-14
北京创立科创医药技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In recent years, there are more and more patients with primary dysmenorrhea. However, most of the Chinese patent medicines on the market are for the treatment of secondary dysmenorrhea. Yu Xuekui develops drug varieties, so it cannot meet the needs of patients

Method used

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  • Traditional Chinese medicinal composition for treating dysmenorrhea and preparation method thereof
  • Traditional Chinese medicinal composition for treating dysmenorrhea and preparation method thereof
  • Traditional Chinese medicinal composition for treating dysmenorrhea and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: the preparation of pharmaceutical preparation

[0032] 1. Formulation

[0033] Angelica (16kg) 16 parts Chuanxiong (14kg) 14 parts Sanqi (8kg) 8 parts

[0034] Motherwort (10kg) 10 parts Peach kernel (5kg) 5 parts Tulip (6kg) 6 parts

[0035] 2. adopt the preparation method provided by the invention to prepare pharmaceutical preparations

[0036] details as follows:

[0037] 1) Take 16 kg of Angelica sinensis and 8 kg of Panax notoginseng and grind them into the coarsest powder, use 80% ethanol as solvent, soak for 24 hours, slowly percolate, collect the initial percolation liquid, and store it in another container; continue percolation until the percolation liquid is nearly Until it is colorless or light yellow, collect the continuous filtrate, combine the filtrate for later use, and collect the filter residue in another device;

[0038] 2) Take 14 kg of Ligusticum chuanxiong and 6 kg of tulips and crush them into the coarsest powder, use ...

Embodiment 2

[0041] Embodiment 2: The influence of the pharmaceutical preparation of the present invention on the thermal stimulation pain threshold of mice

[0042] 1. Test material

[0043] The drug preparation A prepared in Example 1 of the present invention has a content of 12 g crude drug / bag; Fuzhen Tablets, batch number 2120213, provided by Guangxi Hefeng Pharmaceutical Co., Ltd.

[0044] , experimental animals

[0045] Kunming mice, weighing 20±2g.

[0046] , test drug dose

[0047]This experiment adopts intragastric administration, the control group: the same volume of water is given by intragastric administration; the drug preparation A is set up as high, medium and low dosage groups, and the doses are 6g crude drug / kg body weight, 3 crude drug / kg body weight, 1g crude drug / kg body weight; the positive control group is the Fuzhen tablet group: each tablet of Fuzhen tablets weighs 0.26g, and the daily dose is 10 tablets, which is equivalent to 0.39g patent medicine...

Embodiment 3

[0055] Embodiment 3: the influence of the pharmaceutical preparation of the present invention on mice's acetic acid writhing response

[0056] 1. Test material

[0057] The drug preparation A prepared in Example 1 of the present invention has a content of 12 g crude drug / bag; Fuzhen Tablets, batch number 2120213, provided by Guangxi Hefeng Pharmaceutical Co., Ltd.

[0058] , experimental animals

[0059] Kunming mice, weighing 20±2g.

[0060] , test drug dose

[0061] This experiment adopts intragastric administration, the control group: the same volume of water is given by intragastric administration; the drug preparation A is set up as high, medium and low dosage groups, and the doses are 6g crude drug / kg body weight, 3g crude drug / kg body weight, 1g crude drug / kg body weight; the positive control group is the Fuzhen tablet group: each tablet of Fuzhen tablets weighs 0.26g, and the daily dose is 10 tablets, which is equivalent to 0.39g patent medicine / kg body...

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating dysmenorrhea, especially primary dysmenorrhea and a preparation method thereof. The traditional Chinese medicinal composition is mainly prepared from the following raw materials: Angelica sinensis, Ligusticum chuanxiong, Panax notoginseng, Leonurus japonicus, Semen Persicae (Prunus persica and / or Prunus davidiana) and tulip. The traditional Chinese medicinal composition has effects of promoting blood circulation, dispelling blood stasis, regulating menstruation and relieving pain and has definite therapeutic effect. Meanwhile, the invention also provides a preparation method of the traditional Chinese medicinal composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating dysmenorrhea and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating primary dysmenorrhea and a preparation method thereof. Background technique [0002] Dysmenorrhea refers to women who experience obvious cramping pain in the lower abdomen, bloating, or waist pain during menstruation or periodically before and after menstruation. In severe cases, it may be accompanied by nausea and vomiting, cold sweat, cold hands and feet, and even severe pain to fainting. Dysmenorrhea is divided into two types: primary dysmenorrhea and secondary dysmenorrhea. Primary dysmenorrhea refers to dysmenorrhea without organic lesions in organs; while secondary dysmenorrhea refers to dysmenorrhea with organic lesions in reproductive organs. [0003] Epidemiological studies have shown that primary dysmenorrhea is one of the most common gynecologi...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P15/00
Inventor 金倩唐了平郭银汉
Owner 北京创立科创医药技术开发有限公司
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