Method for treating spiramycin zymophyte dreg

A technology of spiramycin and bacterial residue, which is applied in the field of processing spiramycin fermentation waste residue, can solve problems such as unbalanced ratio of antibiotic waste residue, failure to remove antibiotics, hidden dangers in the treatment or application of biogas slurry and biogas residue, and achieve resource utilization. The effect of maximizing utilization, avoiding waste, and reducing the cost of disposal

Inactive Publication Date: 2014-06-11
SHANGHAI INST OF PHARMA IND +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, many production enterprises have used anaerobic method to treat antibiotic wastewater, but there have been no reports on enterprises using anaerobic method to treat antibiotic waste residue
To sum up the reason, the restrictive factors mainly include the following aspects: First, the ratio of carbon and nitrogen in the antibiotic waste residue is unbalanced and the concentration of the two is much higher than that of wastewater treated by the g

Method used

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  • Method for treating spiramycin zymophyte dreg
  • Method for treating spiramycin zymophyte dreg
  • Method for treating spiramycin zymophyte dreg

Examples

Experimental program
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Effect test

Embodiment 1

[0062] Take 1600g of spiramycin residue with a water content of 75%, add water to dilute to 20L, crush the residue with a mixer to form a residue liquid with a solid content of 2%, add sodium hydroxide to adjust the pH to 7.5, and then pour it into In glass jars with a total volume of 40L. Add 13.3L of swamp mud to the fungus residue liquid at an inoculation ratio of 40%, fill it with nitrogen to drive out the air, seal it with a cover, and mix well. Open a small opening from the cork to insert the airway tube, and put the other end of the airway tube into the water for exhaust. The whole device was cultured in an environment with a temperature of 37° C., shaken twice a day, and activated for a total of 15 days.

[0063] According to 1 / 3 of the total volume of 11L in a single tank of the multi-stage anaerobic device, take 3.6L of the mixed biogas slurry from the activated bacteria residue liquid and biogas slurry in the glass tank and add them to the tanks of all levels of th...

Embodiment 2

[0067] Take 1600g of spiramycin residue with a water content of 75%, add water to dilute to 20L, crush the residue with a mixer to form a residue liquid with a solid content of 2%, add sodium hydroxide to adjust the pH to 7.5, and then pour it into In glass jars with a total volume of 40L. Add 13.3L of swamp mud to the fungus residue liquid at an inoculation ratio of 40%, fill it with nitrogen to drive out the air, seal it with a cover, and mix well. Open a small opening from the cork to insert the airway tube, and put the other end of the airway tube into the water for exhaust. The whole device was cultured in an environment with a temperature of 34° C., shaken twice a day, and activated for a total of 15 days.

[0068] According to 1 / 3 of the total volume of 11L in a single tank of the multi-stage anaerobic device, take 3.6L of the mixed biogas slurry from the activated bacteria residue liquid and biogas slurry in the glass tank and add them to the tanks of all levels of th...

Embodiment 3

[0072] Take 1600g of spiramycin residue with a water content of 75%, add water to dilute to 20L, crush the residue with a mixer to form a residue liquid with a solid content of 2%, add sodium hydroxide to adjust the pH to 7.5, and then pour it into In glass jars with a total volume of 40L. Add 13.3 L of swamp mud to the fungus residue liquid at an inoculation ratio of 40%, fill it with carbon dioxide to drive out the air, seal it with a cover, and mix well. Open a small opening from the cork to insert the airway tube, and put the other end of the airway tube into the water for exhaust. The whole device was cultured in an environment with a temperature of 38° C., shaken twice a day, and activated for a total of 15 days.

[0073] According to 1 / 3 of the total volume of 11L in a single tank of the multi-stage anaerobic device, take 3.6L of the mixed biogas slurry from the activated bacteria residue liquid and biogas slurry in the glass tank and add them to the tanks of all level...

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Abstract

The invention provides a method for treating spiramycin zymophyte dreg by virtue of resourceful treatment. The method comprises the following steps: (a) activating outside a tank body; (b) activating inside the tank body; (c) after the activation of slurry in the tank body is ended, replenishing a spiramycin zymophyte dreg liquor through the bottom of a first-grade tank body every day, subsequently sending biogas slurry with the same volume at the top of the first-grade tank body to a second-grade tank body through the bottom of the second-grade tank body, and the like, and finally discharging a feed liquor which has the same volume and is treated by virtue of a multi-stage anaerobic system from the top outlet of a last-grade tank body. The method is simple to operate, low in operating cost and capable of tolerating high organic load and also obviously degrading residual bioactive substances in the zymophyte dreg.

Description

technical field [0001] The invention belongs to the technical field of biological environmental protection, and in particular relates to a method for processing spiramycin fermentation waste residue. Background technique [0002] Spiramycin (Spmycin, SPM) belongs to macrolide antibiotics and was isolated from Streptomyces ambofaciens by the French Rhone-Poulenc laboratory in 1954. Its chemical structure and antibacterial spectrum are similar to erythromycin, its antibacterial activity in vitro is lower than that of erythromycin, but its antibacterial effect in vivo is stronger. Spiramycin is a 16-carbon lactone ring, it is a bacteriostatic agent, and it is bactericidal only at very high concentrations. It is currently generally believed that the key enzyme for the degradation of this type of antibiotic is an esterase that can open the ring of its macrolide structure. The formation of ester bonds is the last step in the formation of macrolide antibiotics, which is catalyzed...

Claims

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Application Information

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IPC IPC(8): C12P5/02C12M1/107
CPCY02E50/30
Inventor 陈代杰李继安朱培张建斌
Owner SHANGHAI INST OF PHARMA IND
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