Preparation of a liquid proliposome composed of squalene and β-carotene and its base reduction and harm reduction
A technology of proliposome and carotene, which is applied in the chemical field, can solve the problems of liquid proliposome preparation technology and application reports, and achieve the effects of large surface area, strong air permeability and increased stability
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Embodiment 1
[0048] Prepare each component according to the following parts by mass: 10 grams (g) of lecithin; Those skilled in the art can use other sources of squalene) 5 grams (g); Those skilled in the art can use 15 grams (g) of β-carotene from other sources; 8 grams (g) of glycerol; 7 grams (g) of hydroxymethyl starch, and 55 grams (g) of water.
[0049] The preparation steps are:
[0050] S1. Dissolving the composition of lecithin, squalene and β-carotene in glycerol to obtain a mixed system;
[0051] S2. Homogenize the mixed system obtained in S1 at high speed (2000r / min, stir for 30min) to make it fully mixed to obtain a homogenized mixed system;
[0052] S3, mix the stabilizer and water to obtain the aqueous solution of the stabilizer, add the aqueous solution of the stabilizer to the homogenized mixed system obtained in S2 and stir evenly to form a stable particle suspension to obtain the combination containing squalene and β-carotene liquid proliposomes.
Embodiment 2
[0054] The preparation steps are the same as in Example 1. Weigh 10 grams of soybean lecithin, 10 grams of squalene, and 10 grams of β-carotene dissolved in 8 grams of glycerol, homogenize at a high speed to make it fully mixed, then add 9 grams of hydroxyethyl starch and dissolve it in 53 grams of water The aqueous solution is stirred evenly to form a stable microparticle suspension, and the liquid proliposome containing the antioxidant squalene and β-carotene composition is obtained.
Embodiment 3
[0056] The preparation steps are the same as in Example 1. Weigh 10 grams of hydrogenated soybean lecithin, 15 grams of squalene, 5 grams of β-carotene dissolved in 8 grams of glycerol, homogenize at high speed to make it fully mixed, then add 5 grams of hydroxymethyl starch and dissolve in 57 grams of The aqueous solution of water is stirred evenly to form a stable microparticle suspension, that is, the liquid proliposome containing the composition of antioxidant squalene and β-carotene is obtained.
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