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Pharmaceutical composition, preparation method, preparation and application thereof

A composition and medicine technology, applied in the field of pharmaceutical compositions and their preparation, can solve the problems of destroying the normal flora of the human body, edema, overgrowth of insensitive microorganisms and the like

Inactive Publication Date: 2014-07-16
张庆芬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

④Large doses of medication can easily lead to edema
⑤ Long-term use will destroy the normal flora of the human body, leading to the overgrowth of insensitive microorganisms and multiple infections

Method used

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Examples

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preparation example Construction

[0039] The preparation method of the pharmaceutical composition of the present invention includes the steps of pretreatment, extraction, concentration and drying, specifically including:

[0040] A. Pretreatment: Coarsely pulverize the raw materials and mix them for later use;

[0041] B. Extraction: add water with a weight ratio of 4 to 8 times to the raw material coarse powder to extract 2 to 4 times, filter, and combine the filtrate;

[0042] C. Concentration: Concentrate and dry the filtrate to obtain the target substance.

[0043] The coarse pulverization described in step A is to pulverize through a 10 mesh sieve.

[0044] The extraction temperature described in step B is 90-150° C., and the extraction time is 40-80 minutes.

[0045] The concentration described in step C is vacuum low-temperature concentration, and the described drying is low-temperature drying.

[0046] The preparation of the pharmaceutical composition of the present invention is to add pharmaceutica...

Embodiment 1

[0054] Coarsely crush 10Kg of litchi skin and 100Kg of Houttuynia cordata through a 10-mesh sieve, mix well, add water with a weight ratio of 4 times, extract 4 times at 90°C, filter, and combine the filtrate; concentrate the filtrate at 60°C , Dry below 85°C to get the target product.

Embodiment 2

[0056] Coarsely crush 30Kg of litchi core and 800Kg of Houttuynia cordata through a 10-mesh sieve, mix well, add water with a weight ratio of 8 times, extract twice at 150°C, filter, and combine the filtrate; concentrate the filtrate at 60°C , Dry below 85°C to get the target product.

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Abstract

The invention discloses a pharmaceutical composition, a preparation method, a preparation and application thereof. The pharmaceutical composition comprises the following raw medicines in parts by weight: 10 to 30 parts of litchi rind / seed, and 100 to 800 parts of houttuynia cordata. The pharmaceutical composition is prepared by pre-processing, extracting, concentrating and drying the raw medicines. The method comprises the steps of pre-processing, extracting, concentrating and drying. The preparation is characterized in that pharmaceutically acceptable auxiliary materials are added to the pharmaceutical composition to prepare into powder, tablet, capsule, particles, dropping pill or honeyed pill. The application is the application of the pharmaceutical composition in preparation of medicines for treating nephritis, nephropyelitis, urinary tract infection and cystolith. The pharmaceutical composition is prepared from low-cost Chinese herbal medicines and can overcome the shortage and side effects of the existing medicines. The pharmaceutical composition not only can act fast, but also be short in medication cycle, and also shows a good effect on treating nephritis, nephropyelitis, urinary tract infection, cystolith, pelvic inflammation, mastitis, etc.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparation, and in particular relates to a pharmaceutical composition, a preparation method, preparation and application thereof. Background technique [0002] Nephritis, pyelonephritis, prostatitis, pelvic inflammatory disease, urinary tract infection, and bladder stones are common diseases of the kidney and bladder urinary system. The kidney is an important organ of the human body. If the drug is not used in time and attention is not paid, the result will be renal failure and even death. [0003] The current clinical treatment of nephritis, pyelonephritis and urinary tract infection by Western medicine: [0004] 1. Gentamicin: The main side effect of gentamicin is damage to the auditory nerve and kidneys. Hematuria, significantly decreased frequency of urination or decreased urine output, loss of appetite, extreme thirst and other nephrotoxic reactions may also occur. ① O...

Claims

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Application Information

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IPC IPC(8): A61K36/78A61K36/899A61K36/85A61K36/88A61P13/12A61P13/08A61P13/00A61P13/04A61P31/04A61P15/00A61P9/14A61P15/14A61P1/00
Inventor 张庆芬
Owner 张庆芬
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