Method for preparing coating on surface of intervention catheter, intervention catheter and interventional device

An interventional catheter and coating technology, applied in the field of medical devices, can solve the problems of easy falling off and poor coating firmness, and achieve the effects of ensuring firmness, enhancing abrasion resistance and excellent lubrication effect.

Inactive Publication Date: 2014-07-23
BEIJING DEMAX MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, the hydrophilic lubricity of the interventional catheter is generally enhanced by preparing a coating on the surface of the interventional catheter, but most of the coatings are poor in firmness and are easy to fall off during use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0033] Preparation method of the present invention comprises the steps:

[0034] S100, pretreatment: perform plasma treatment on the surface of the interventional catheter, the treatment process is:

[0035] The intervention catheter is placed in the sample chamber of the plasma generator, and the gas is passed in, wherein the gas passed in is preferably one or more of helium, argon, oxygen or nitrogen, which has stable chemical properties and is not easy to Reacts with substrates of interventional catheters.

[0036] During the treatment process, there are no special restrictions on the power and treatment time of the plasma generator, which depends on the substrate and process requirements of the interventional catheter. As a possible implementation, the power of the plasma generator is preferably 10W-300W , the processing time is preferably 1 min to 5 min; after the processing is completed, the interventional catheter is taken out for use.

[0037] After plasma treatment,...

Embodiment 1

[0054] (1) Coating preparation: Add water-based polyurethane, trimethylolpropane-tris[3-(2-methylaziridinyl)]propionate, polyether-modified polysiloxane, and deionized water to the container In, stirred at room temperature for 30 minutes to obtain a primer; Polymethyl vinyl ether-maleic anhydride, acrylic acid, hydroxyethyl acrylate, trimethylolpropane triacrylate, photoinitiator and N,N-di Methylformamide was added to the container and stirred at room temperature for 30 minutes to obtain a top coat;

[0055] In the primer, the quality of trimethylolpropane-tris[3-(2-methylaziridinyl)] propionate is 1% of the waterborne polyurethane quality, and the quality of polyether modified polysiloxane is The mass of waterborne polyurethane is 0.1%, and the mass of deionized water is 80% of the total mass of the primer.

[0056] In the top coat, the mass of acrylic acid is 2% of the mass of polymethyl vinyl ether-maleic anhydride, the mass of hydroxyethyl acrylate is 5% of the mass of p...

Embodiment 2

[0066] (1) Coating preparation: Add water-based polyurethane, trimethylolpropane-tris(3-aziridinyl)propionate, polyether-modified polysiloxane, and deionized water into the container, and stir at room temperature In 20 minutes, the primer coating was obtained; polymethyl vinyl ether-maleic anhydride, acrylic acid, hydroxyethyl acrylate, pentaerythritol triacrylate, photoinitiator, N,N-dimethylacetamide were added to the container, and the Stir at room temperature for 30 minutes to obtain a top coat;

[0067] In the primer, the mass of trimethylolpropane-tris(3-aziridinyl)propionate is 2% of the mass of water-based polyurethane, and the mass of polyether-modified polysiloxane is 0.2% of the mass of water-based polyurethane , the mass of deionized water is 85% of the total mass of the primer; in the top coat, the mass of acrylic acid is 1% of the mass of polymethylvinyl ether-maleic anhydride, and the mass of hydroxyethyl acrylate is 1% of that of polymethylvinyl 5% of the qual...

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Abstract

The invention discloses a method for preparing a coating on the surface of an intervention catheter, an intervention catheter and an interventional device, the method comprises the following steps: firstly, performing plasma treatment on the surface of the intervention catheter, then grafting acrylic acid on the plasma treated surface of the intervention catheter; preparing a base painting and a top painting; coating the surface of the intervention catheter respectively with the prepared the base painting and top painting; and post treating the intervention catheter to obtain the intervention catheter with a hydrophilic lubricating coating on the surface. The intervention catheter has excellent hydrophilic lubricity and firmness.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a method for preparing a coating on the surface of an intervention catheter, an intervention catheter and an intervention device. Background technique [0002] Endovascular interventional diagnosis and treatment technology is widely used in clinical angiography, angioplasty, removal of intravascular thrombus or foreign body, etc. Compared with traditional medical technology, endovascular interventional diagnosis and treatment technology is not only convenient to operate, but also because of the low trauma of interventional treatment, it can reduce the pain of patients, the risk of treatment is small, and the cost of treatment is relatively low. Therefore, this technology is widely used in medicine. field has been widely promoted and used. Intravascular interventional diagnosis and treatment technology uses interventional catheters to reach distant diseased parts in the body, such ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L29/08B05D5/00B05D3/10B05D3/00B05D3/02B05D7/24
Inventor 王兴元贾登强
Owner BEIJING DEMAX MEDICAL TECH
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