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Preparation method of contact lens and method for monitoring intraocular pressure using contact lens

A contact lens and intraocular pressure technology, applied in tonometers, applications, household appliances, etc., can solve the problems of unaffordable, inability to real-time intraocular pressure monitoring, and complex structure design for middle and low-level groups, achieving low cost and improving vision. Deteriorating, simple-structured effects

Active Publication Date: 2017-06-13
SHENZHEN INST OF ADVANCED TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the intraocular pressure detectors currently used clinically cannot monitor the intraocular pressure in real time.
At present, although there are a few smart contact lenses for real-time monitoring of intraocular pressure, all of them require electric drive and signal processing, and the structural design is complex, which is extremely inconvenient to use and very expensive, which is difficult for middle- and low-class groups.

Method used

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  • Preparation method of contact lens and method for monitoring intraocular pressure using contact lens
  • Preparation method of contact lens and method for monitoring intraocular pressure using contact lens

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Experimental program
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Effect test

Embodiment approach

[0033] Such as figure 1 Shown, the preparation method of the contact lens of the present application, one embodiment thereof, comprises the following steps:

[0034] Step 102: Formulate the monodisperse microspheres into an emulsion.

[0035] Disperse the monodisperse colloidal nanoparticles in water and configure to obtain a colloidal emulsion with a mass fraction of 0.001% to 10%. Monodisperse microspheres include polystyrene, polymethyl methacrylate, silicon dioxide, titanium dioxide, iron oxide, ferric oxide, gold and silver, or any combination of more. Specifically, it can be microspheres of polystyrene, polymethyl methacrylate, silicon dioxide, titanium dioxide, iron oxide, ferric oxide, gold, silver, or polystyrene, polymethyl methacrylate, di Modified microspheres of silicon oxide, titanium dioxide, iron oxide, iron oxide, gold, silver, or polystyrene, polymethyl methacrylate, silicon dioxide, titanium dioxide, iron oxide, iron oxide, gold , Silver composite microsp...

Embodiment 1

[0061] 1. Preparation of colloidal photonic crystal particles:

[0062] 10 mL of monodisperse polystyrene microspheres with a diameter of 180 nm were formulated into an emulsion with a mass concentration of 5.0 wt%, dispersed ultrasonically, and then added to the mold used to prepare contact lenses, and the mold was placed in an oven at 50 °C In 30 minutes, you can get up and down through the colloidal crystals.

[0063] 2. Curing treatment of prepolymer solution:

[0064] 100 microliters of contact lens prepolymer mixture: methyl methacrylate (95% by mass), ethylene glycol dimethacrylate (4.8% by mass) and UV initiator Irgacure 2959 (mass fraction: 0.2%) into the mold, let it stand for 30 minutes until the prepolymer fully infiltrates the colloidal crystal, and then UV cross-linking at 0 degrees Celsius for 1 hour, that is, the initial contact lens product is cured.

[0065] 3. Hydration treatment of contact lenses:

[0066] After demolding the initial product of the conta...

Embodiment 2

[0068] 1. Preparation of colloidal photonic crystal particles:

[0069] 10 mL of monodisperse silica microspheres with a diameter of 220 nanometers were formulated into an emulsion with a mass concentration of 0.1 wt%, dispersed ultrasonically, and then added to the lower mold used to prepare contact lenses, and the lower mold was left to stand at 50 °C oven for 30 minutes to obtain the penetrating colloidal crystals.

[0070] 2. Curing treatment of prepolymer solution:

[0071] Add 100 microliters of the contact lens prepolymer mixture: the mixed solution of hydroxyethyl methacrylate and methylene bisacrylamide (molar ratio 30:1), and add Irgacure 2959 (mass concentration: 0.2%) as the initiator Put it into the mold, let it stand for 30 minutes until the prepolymer fully infiltrates the colloidal crystal, and then perform ultraviolet crosslinking at 0 degrees Celsius for 1 hour, and then the initial contact lens product is cured.

[0072] 3. Hydration treatment of contact l...

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Abstract

The invention discloses a method for manufacturing a contact lens and a method for monitoring eye pressure by using the contact lens. The method for monitoring eye pressure comprises the steps of wearing the contact lenses containing photonic crystal into eyes and monitoring the eye pressure through observation of the color of the contact lens. The contact lens contains photonic crystal; when being worn, the contact lens can represent different colors according to different eye pressures so as to monitor the eye pressure. According to the monitoring method, electronic driving and signal processing are not needed; the manufactured contact lens is simple in structure, convenient to use and low in cost; not only are new thoughts and methods for early preventing, monitoring and treating glaucoma provided, but also the current situation that the eyesight of glaucoma patients get worse and worse in China is remarkably improved; the method for monitoring eye pressure by using the contact lens has a wide application prospect in the fields of medical instruments, pharmaceutical researches and the like.

Description

technical field [0001] The present application relates to the technical field of contact lenses, in particular to a method for preparing a contact lens and a method for monitoring intraocular pressure using the contact lens. Background technique [0002] Glaucoma is the world's first irreversible blinding eye disease, and its most important risk factor is pathological elevated intraocular pressure. Therefore, real-time intraocular pressure monitoring is of great significance for the diagnosis and treatment of glaucoma. According to the survey until 2010, there were about 67 million glaucoma patients in the world, and about 15 million glaucoma patients in China. It is estimated that by 2020, the number of glaucoma patients in the world will increase to 79.6 million, while the number of glaucoma patients in China will rise to 21.8 million. China will be the largest in the world. Countries with the most glaucoma patients. [0003] However, none of the tonometry instruments cu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B29D11/00A61B3/16
Inventor 杜学敏吴天准李腾跃
Owner SHENZHEN INST OF ADVANCED TECH
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