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Plant extract composition with liver protection function

A plant extract and liver protection technology, applied in the field of functional plant extract composition, can solve problems such as low liver function and physical diseases, and achieve the effect of strong function, scientific and reasonable compound ratio, and low toxicity

Inactive Publication Date: 2014-08-13
葛存旺
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, once the amount of harmful substances exceeds the processing capacity of the liver, it will lead to low liver function and cause the body to suffer from disease

Method used

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  • Plant extract composition with liver protection function

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1 novel plant extract composition is to carbon tetrachloride (CCl 4 )-induced liver damage

[0024] Wistar rats were divided into 5 groups (normal control group, CCl 4 Model group, plant extract composition experimental group). Each control group and model group were gavaged with physiological saline, and the experimental group was given a plant extract composition (1: 20: 20, 1: 35: 35, 1: 50: 50) (0.086 mg / kg in terms of savorprofen). ) of the plant extract composition suspension was gavaged, every 12h was gavaged 2 times, and after continuous gavage for 7 days, the model group and the experimental group were intraperitoneally injected with 30% CCl 4 Olive oil solution (1.5ml / kg), the normal group was given the same amount of olive oil.

[0025] 16 hours later, detect serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP); Purine oxidase method and thiobarbituric acid method were used to detect superoxide dism...

Embodiment 2

[0028] Embodiment 2 novel plant extract composition tablet

[0029] Tablet prescription:

[0030]

[0031]Preparation method: according to the prescription, take broccoli extract, add citric acid, microcrystalline cellulose, mix well, add milk thistle extract, turmeric extract, lactose, low-substituted hydroxypropyl cellulose, mix well, add 2 50% ethanol solution of povidone is made into soft materials, granulated through 24 nylon sieves, dried at 60°C, granulated with 20 mesh nylon sieves, colloidal silicon dioxide and talcum powder are added, mixed evenly, and pressed into tablets to obtain the product. The hardness is controlled at 6-11kgf, and each tablet contains 1 mg of savprofen.

Embodiment 3

[0032] Embodiment 3 Novel plant extract composition soft capsule

[0033] Contents Prescription:

[0034]

[0035] Preparation method: According to the prescription, dissolve polysorbate 80 and butyl hydroxyanisole in 250ml of medium chain oil, add broccoli extract, milk thistle extract, turmeric extract, grind to dissolve or disperse, add medium chain oil to 300m1, evenly ground. Prepare gelatin solution (100 parts of gelatin, 55 parts of glycerin, 120 parts of water, 0.5 part of titanium dioxide) for later use. Under the conditions of room temperature 23±2°C and relative humidity of 40%, the medicine solution and gelatin solution are made into soft capsules by a soft capsule machine. Capsules are filled with 0.3ml of content per pill, and dried for 20 hours at 28±2°C and relative humidity of 40%.

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Abstract

The invention relates to a plant extract composition for protecting liver. The composition contains components such as sulforaphane, silymarin and curcumin, etc. The sulforaphane is an extract from crucifers such as broccoli seed, cauliflower and the like. The silymarin is an extract from compositae medical plants such as silybum marianum and the like. The curcumin is an extract from plants such as turmeric, etc. The plant extract composition is a compound composed of sulforaphane, silymarin and curcumin according to the weight ratio of 1:10-50:10-50, and is a novel health product with a liver protection function.

Description

technical field [0001] The invention relates to a functional plant extract composition, in particular to a novel compound liver-protecting and health-care product and medicine with liver-protecting function. Background technique [0002] One of the main roles of the liver is "detoxification". The so-called "detoxification" means that the liver will wrap up the chemical substances absorbed into the body in daily life and excrete them from the body. This is an important function of the liver. [0003] The human body absorbs various harmful substances such as viruses or drugs through breathing, eating, smoking and drinking every day. The liver is responsible for detoxifying these harmful substances. However, once the amount of harmful substances exceeds the processing capacity of the liver, it will lead to low liver function and cause the body to suffer from disease. Therefore, improving the detoxification function of the liver is important for maintaining health. [0004] ...

Claims

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Application Information

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IPC IPC(8): A61K31/357A23L1/29A61P1/16A61K31/26A61K31/12A23L33/00
Inventor 葛存旺蒋曙光陆宏卿舒丽
Owner 葛存旺
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