In-vivo microendoscopic spectral imaging system

Abstract

The invention belongs to the technical field of optical imaging, and particularly relates to an in-vivo microendoscopic spectral imaging system. The in-vivo microendoscopic spectral imaging system comprises a light source unit, a light split unit, an endoscopic unit, a dispersion unit, a detection unit and a computer unit, wherein the dispersion unit comprises a dispersion device and a dispersion device controller which controls the dispersion device to achieve gating of signals with different wave lengths; and the dispersion device adopts an acousto-optic adjustable filter, a liquid-crystal adjustable filter or a thin-film adjustable filter. The in-vivo microendoscopic spectral imaging system is relatively simple in structure, smaller in size and more convenient to use; subcellular-resolution imaging can be performed on the inner surface of an in-vivo tract organ through introduction of an imaging optical fiber bundle; and more importantly, the dispersion device adopts a full-seal design and does not have a movable part, so that the environmental adaptability of the equipment is improved greatly, and the system works more stably.

Description

technical field [0001] The invention belongs to the technical field of optical imaging, and in particular relates to a living body microendoscopic spectral imaging system. Background technique [0002] Tumor is a major disease that seriously threatens human health. In the past 30 years, the incidence of cancer (malignant tumor) in the world has been increasing at an average annual rate of 3% to 5%. Cancer has become one of the most important causes of death for human beings. Clinical experience shows that the earlier the diagnosis of cancer is, the higher the survival rate of cure is, so microendoscopic technology that can achieve high-resolution imaging close to tissue biopsy has attracted more and more attention. Traditional imaging methods, usually only imaging diagnosis can only provide spatial shape information. The spectral diagnosis relies on obtaining the optical radiation signal at a certain wavelength to identify the information of the biochemical composition of ...

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Problems solved by technology

[0003] However, the spectral imaging system in the prior art is quite complex, bulky, and expensive, and it is often difficult to meet the requirements of accurate diagnosis due to problems such as stability, resolution, accuracy, and susceptibility to the surrounding environment, making the existing microscopic imaging system It is difficult to achieve ideal results by combining imaging diagnosis and spectroscopy diagnosis

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