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Emulsifiable paste for treating urticaria papulosa and preparation method thereof

A technique for treating urticaria and papular urticaria, applied in the field of cream for treating papular urticaria and its preparation, can solve the problems of strong skin irritation, frequent and repeated attacks, and long treatment time, so as to reduce intradermal edema, Elimination of allergic reactions and the effect of reducing permeability

Inactive Publication Date: 2014-10-15
王卫武
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a kind of cream for treating papular urticaria in order to solve the technical problems of long treatment time, low cure rate, frequent relapse, and great irritation to the skin in the prior art.

Method used

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  • Emulsifiable paste for treating urticaria papulosa and preparation method thereof

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Effect test

Embodiment 1

[0017] A kind of cream for treating papular urticaria, which is made of the following raw materials in parts by weight: 1 g of hydrocortisone butyrate; 17 g of erythromycin lactobionate; 9 g of chlorpheniramine maleate; 60 g of glycerin g; Vaseline 155 g; cetyl alcohol 95 g; liquid paraffin 105 g;

[0018] The preparation method of the emulsifiable paste for treating papular urticaria comprises the following steps: A, matrix preparation: take auxiliary materials glycerin 60 g, vaseline 155 g, cetyl alcohol 95 g, liquid paraffin 105 g, ethylparaben 0.5 g, purify Put 610 g of water in a container, heat to 85°C, then add 20 g of Pingping O, stop heating, stir evenly until condensed, and you can get an O / W cream base; B. Cream preparation: take the powder raw material Add 1g of hydrocortisone, 17g of erythromycin lactobionate, and 9g of chlorpheniramine maleate into the O / W cream base described in step A, and stir evenly; C, packaging: take 15g separately The cream is packaged in...

Embodiment 2

[0021] A kind of cream for treating papular urticaria, which is made of the following raw materials in parts by weight: hydrocortisone butyrate 2g; erythromycin lactobionate 13g; chlorpheniramine maleate 7g; glycerin 65g; petrolatum 145g; cetyl alcohol 105g; liquid paraffin 95g; Pingpingjia O 30g; ethylparaben 1.5g; purified water 590g.

[0022] The preparation method of the emulsifiable paste for treating papular urticaria comprises the following steps: A, matrix preparation: take auxiliary materials glycerin 65 g, vaseline 145 g, cetyl alcohol 105 g, liquid paraffin 95 g, ethylparaben 1.5 g, purify Put 590 g of water in a container, heat to 90°C, then add 30 g of Pingping O, stop heating, stir evenly until condensed, and you can get an O / W cream base; B. Cream preparation: take the powder raw material D Add 2g of hydrocortisone, 13g of erythromycin lactobionate, and 7g of chlorpheniramine maleate into the O / W cream base described in step A, and stir evenly; C, packaging: tak...

Embodiment 3

[0025] A cream for treating papular urticaria, which is made of the following raw materials in parts by weight: 1.5 g of hydrocortisone butyrate; 15 g of erythromycin lactobionate; 8 g of chlorpheniramine maleate; 63 g of glycerin; Petroleum jelly 150g; Cetyl alcohol 100g; Liquid paraffin 100g; Pingpingjia O 25g; Ethylparaben 1g;

[0026] Its preparation method for treating papular urticaria emulsifiable paste comprises the following steps: A, matrix preparation: get auxiliary materials glycerin 63g, petrolatum 150g, cetyl alcohol 100g, liquid paraffin 100g, ethylparaben 1g, purified water 600g and place in container Inside, heat to 88°C, then add 25g Pingping plus O, stop heating, stir evenly until condensed, you can get O / W cream base; B, cream preparation: Take 1.5g powder raw material hydrocortisone butyrate 15g of erythromycin lactobionate and 8g of chlorpheniramine maleate are added to the O / W cream base described in step A, and stirred evenly; C, packaging: 15g of cream...

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Abstract

The invention discloses an emulsifiable paste for treating urticaria papulosa. The emulsifiable paste is prepared from the following raw materials in parts by weight: 1 to 2 parts of butyric acid hydrocortisone, 13 to 17 parts of erythromycin lactobionate, 7 to 9 parts of chlorpheniramine maleate and 1000.5 to 1071.5 parts of auxiliary materials. The preparation method comprises the following steps: A) substrate preparation: taking the auxiliary materials of 63 parts of glycerinum, 150 parts of vaseline, 100 parts of cetanol, 100 parts of liquid paraffin, 1 part of hydroxy benzene acetic acid and 600 parts of purified water, placing into a vessel, heating at the temperature of 85 to 90 DEG C, then, adding 25 parts of leveling agent O, stopping heating, and stirring uniformly until generation of condensation so as to acquire O / W type emulsifiable paste substrate; B) emulsifiable paste preparation: taking powder raw materials of 1.5 parts of the butyric acid hydrocortisone, 15 parts of the erythromycin lactobionate and 8 parts of the chlorpheniramine maleate, adding into the O / W type emulsifiable paste substrate in step A, and stirring uniformly; C) packaging: respectively taking 15 parts of the emulsifiable paste, and sub-packaging with plastic cases. According to the emulsifiable paste, stimulation reaction and anaphylactic reaction of skin can be avoided; besides, the emulsifiable paste is short in therapy time-effect, high in cure rate, simple in preparation process, convenient to produce and process and definite in therapy effect.

Description

technical field [0001] The invention belongs to the technical field of western medicine, and in particular relates to a cream for treating papular urticaria and a preparation method thereof. Background technique [0002] Papular urticaria is a disease named after its symptoms. It is also known as urticarial moss and baby moss. It is a delayed allergic skin disease related to insect bites. It is more common in infants and children. The trunk is more common in spring, summer and autumn. The disease is characterized by round, oval or spindle-shaped red wheal-like papules with blisters or bullae on the top and small pit marks bitten by blood-sucking insects. There is no redness around. The number is indefinite, scattered distribution, also clustered but not fused, due to severe itching and scratching and skin damage secondary to impetigo, boils and other infectious skin diseases. The etiology is related to exogenous allergic reactions to bites of bedbugs, fleas, lice, mites, mo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61P37/08A61P17/00A61P17/04A61P29/00A61P31/04A61K31/573A61K31/4402
Inventor 王卫武
Owner 王卫武
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