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Medicine and method for treating acute and chronic allergic and congestive skin diseases

A skin disease and drug technology, applied in the field of non-hormonal drugs for the treatment of acute and chronic allergic and congestive skin diseases, can solve the problems of long treatment course, rebound phenomenon, repeated dermatitis, etc., and achieve the effect of excellent curative effect and low cost

Active Publication Date: 2016-04-27
董颖颖
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] (3) secondary telangiectasia, resulting in recurrent dermatitis;
[0011] (6) Long-term large-scale use can easily lead to calcium deficiency and low potassium
[0015] (1) Prone to allergic reactions such as itching, redness, burning, scaling and contact dermatitis;
[0016] (2) The onset of effect is slow, and most of them have no obvious curative effect on redness, swelling, heat and itching of dermatitis, and can only be used to consolidate the therapeutic effect.
[0020] (1) The active ingredient and mechanism are not clear;
[0021] (2) Stimulation reactions are common, and even cause the aggravation of the primary disease, so it is generally not used alone;
[0022] (3) The curative effect is not clear;
[0023] (4) Some drugs can cause photosensitivity
[0027] (1) Suppresses the immune response, and there is a risk of secondary infection, such as local folliculitis and herpes; long-term and large-scale use can inhibit the immune response through systemic absorption, and there is a risk of systemic infection or tumor;
[0028] (2) Some patients are effective, the course of treatment is longer, and there is a rebound phenomenon after stopping the drug;
[0029] (3) Multiple stimulation reactions

Method used

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Embodiment Construction

[0039] In one embodiment, the present invention discloses a medicine for external use for treating skin diseases, characterized in that: said medicine at least includes diphenhydramine hydrochloride, epinephrine hydrochloride and lidocaine hydrochloride, and the weight ratio of the three is 1.25- 10: 0.025-0.5: 2.5-25.

[0040] In terms of this embodiment, the basic technical scheme of the present invention and the inventor's clinical experience have been disclosed:

[0041] (1) Diphenhydramine hydrochloride, blocking peripheral H1 receptors: It has a strong inhibitory effect on telangiectasia, increased permeability, and local edema caused by histamine. Diphenhydramine hydrochloride is non-irritating to skin tissue and works quickly. The inventor found in clinical treatment that when the drug is used systemically, the effective drug concentration is lower in the local skin lesions, and the onset of effect is slower; while the local application can easily reach the effective ...

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PUM

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Abstract

The invention discloses an external medicine for treating skin diseases. The medicine is characterized by at least comprising diphenhydramine hydrochloride, epinephrine hydrochloride and lidocaine hydrochloride in a weight ratio of (1.25-10):(0.025-0.5):(2.5-25). The medicine is a non-hormone external medicine which can be used for effectively treating acute and chronic allergic and congestive skin diseases, autoimmune skin diseases and the like.

Description

technical field [0001] The invention relates to the field of dermatological drugs, in particular to a non-hormonal drug and method for treating acute and chronic allergic and congestive skin diseases. Background technique [0002] At present, the most commonly used topical drugs for the treatment of acute and chronic allergic skin diseases include: glucocorticoids, non-steroidal anti-inflammatory drugs, traditional Chinese medicine extracts and immunosuppressants. [0003] 1. For external use of glucocorticoids (representative drugs: halometasone cream, mometasone furoate cream, desonide cream and hydrocortisone butyrate cream, etc.), it has the following characteristics: [0004] Advantages: many types, wide application, fast curative effect; [0005] shortcoming: [0006] (1) prone to secondary infections, such as viral warts, herpes simplex, impetigo, folliculitis, etc.; [0007] (2) Secondary skin atrophy and thinning, and atrophy lines appear; [0008] (3) secondary...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/167A61P17/00A61P17/06A61K31/137A61K31/135
Inventor 董颖颖
Owner 董颖颖
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