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Method for extracting ginsenoside, and prepared ginsenoside extract

A technology of ginsenosides and extracts, which is applied to medical preparations containing active ingredients, drug combinations, and pharmaceutical formulas, and can solve problems such as high cost, high energy consumption, and low yield, and achieve increased yield and reduced content , the effect of reducing loss

Active Publication Date: 2014-12-10
杨凌萃健生物工程技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This traditional reflux extraction process has the disadvantages of high energy consumption, low yield, high cost, and low ginsenoside content.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1. Raw material processing: Ginseng stems and leaves are screened to remove other foreign matter (such as iron wire, weeds, silt, etc.), and then crushed and cut into sections, which are 2 to 3 cm in size for later use.

[0026] 2. Raw material extraction:

[0027] 2.1 The extraction solvent is water.

[0028] 2.2 Extraction process: Put the processed raw materials into the extraction tank, add water for forced circulation extraction, repeat the extraction 3 times, and combine the extraction liquid: for the first extraction, the extraction solvent is 10 times the weight of the raw material, and the extraction temperature is 70°C , the extraction time was 1.5 hours; for the second extraction, the extraction solvent was 10 times the weight of the raw material, the extraction temperature was 75°C, and the extraction time was 2 hours; for the third extraction, the extraction solvent was 10 times the weight of the raw material, the extraction temperature was 80°C, and the ex...

Embodiment 2

[0042] 1. Raw material processing: Ginseng stems and leaves are screened to remove other foreign matter (such as iron wire, weeds, silt, etc.), and then crushed and cut into sections, the size of which is 3 cm for later use.

[0043] 2. Raw material extraction:

[0044] 2.1 The extraction solvent is methanol solution with a mass fraction of 30%.

[0045]2.2 Extraction process: Put the processed raw materials into the extraction tank, add the extraction solvent for forced circulation extraction, repeat the extraction 3 times, and combine the extraction solution: for the first extraction, the extraction solvent is 10 times the weight of the raw material, and the extraction temperature is 70 ℃, the extraction time is 1.5 hours; for the second extraction, the extraction solvent is 10 times the weight of the raw material, the extraction temperature is 75 ° C, and the extraction time is 2 hours; for the third extraction, the extraction solvent is 10 times the weight of the raw mater...

Embodiment 3

[0059] 1. Raw material processing: Ginseng stems and leaves are screened to remove other foreign matter (such as iron wire, weeds, silt, etc.), and then crushed and cut into sections, the size of which is 3 cm for later use.

[0060] 2. Raw material extraction:

[0061] 2.1 The extraction solvent is an ethanol solution with a mass fraction of 30%.

[0062] 2.2 Extraction process: Put the processed raw materials into the extraction tank, add the extraction solvent for forced circulation extraction, repeat the extraction 3 times, and combine the extraction solution: for the first extraction, the extraction solvent is 10 times the weight of the raw material, and the extraction temperature is 70 ℃, the extraction time is 1.5 hours; for the second extraction, the extraction solvent is 10 times the weight of the raw material, the extraction temperature is 75 ° C, and the extraction time is 2 hours; for the third extraction, the extraction solvent is 10 times the weight of the raw ma...

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PUM

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Abstract

The invention discloses a method for extracting ginsenoside. The method comprises the steps as follows: raw material processing; extracting through an extraction solvent; processing extracting solution; adsorption refining through resin; alkali washing and impurity removing; ingredient eluting; eluent decolorizing; concentrating, and the like. According to the method, through adopting the given alkali washing and impurity removing technology, and combing with the corresponding method of water-extracting or alcohol extracting, the product yield of the prepared ginsenoside extract is improved greatly and can reach as high as 7-7.5%, and the ginsenoside (Rb1+Rb2+Rc+Rd+Re+Rg1) content of the ginsenoside extract is equal to and larger than 45%.

Description

technical field [0001] The invention belongs to the technical field of important extraction, and specifically relates to a method for extracting ginsenosides and a prepared ginsenoside extract. Background technique [0002] Ginsenoside is a kind of sterol compound, triterpene saponin. It is mainly found in ginseng medicinal materials. Ginsenosides are considered to be the active ingredients in ginseng and thus have been the subject of research. [0003] The total saponins of ginseng stems and leaves are the total saponins processed from the dried stems and leaves of ginseng. It has a slight odor and a bitter taste. The main ingredients are ginsenosides Rg1, Re, Rc, Rb1, Rb2, Rd, etc., which have the functions of nourishing and strengthening, calming the nerves and improving intelligence, and enhancing immunity. [0004] Traditional ginsenoside extraction methods mainly include water extraction or alcohol extraction to prepare total saponins. This traditional reflux extra...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61P37/04A61P1/14
Inventor 胡洪来李文芳何锦伟程盼盼
Owner 杨凌萃健生物工程技术有限公司
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