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A detection method for drugs for treating irritable bowel syndrome

A technology for irritable bowel syndrome and detection method, which can be used in drug combinations, pharmaceutical formulations, measuring devices, etc., can solve the problems of unclear pathogenesis of IBS, abnormal visceral sensation, and complex pathogenesis.

Active Publication Date: 2017-04-12
叶祖光
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. Visceral paresthesia
[0004] At present, the pathogenesis of IBS is still unclear. Due to the complexity of the pathogenesis, there is no effective treatment method in modern medicine. Nowadays, most clinical treatments are mainly symptomatic, and there is no single drug that can effectively treat IBS.

Method used

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  • A detection method for drugs for treating irritable bowel syndrome
  • A detection method for drugs for treating irritable bowel syndrome
  • A detection method for drugs for treating irritable bowel syndrome

Examples

Experimental program
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Embodiment 1

[0239] Embodiment 1: the detection method of granule is

[0240] Granule formula: Bupleurum 250g, fried white peony root 300g, fried Atractylodes macrocephala 280g, Fangfeng 300g, fried citrus aurantium 200g, fried tangerine peel 200g, black plum 200g, coptis 133g, roasted licorice 133g

[0241] Process: Weigh Bupleurum, fried white peony root, fried Atractylodes macrocephala, Fangfeng, fried citrus aurantium, fried tangerine peel, coptis, and roasted licorice according to the prescription. Once for 1 hour, filter, combine the filtrates, concentrate to 80°C with a relative density of 1.15-1.25 extract, dry at 60°C, 0.07Mpa-0.08Mpa, and grind into fine powder after drying; add 10 times the amount of water to ebony for later use , decocted twice, each time for 1 hour, filtered, combined filtrates, concentrated to 80°C extract with a relative density of 1.15-1.25, dried at 60°C, 0.07Mpa-0.08Mpa environment, after drying, crushed into fine powder and Mix the fine powders of the r...

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Abstract

The invention discloses a method for detecting a medicinal oral preparation for treating irritable bowel syndrome. The medicinal oral preparation is mainly prepared from radix bupleuri, fried radix paeoniae alba, roasted rhizoma atractylodis macrocephalae, saposhnicovia divaricata, roasted fructus aurantii immaturus, roasted pericarpium citri reticulatae, fructus mume, coptis chinensis and honey-fried licorice root, as well as auxiliaries. The detection method comprises the following steps: carrying out thin-layer chromatography identification on roasted rhizoma atractylodis macrocephalae, roasted pericarpium citri reticulatae, roasted fructus aurantii immaturus, fructus mume and honey-fried licorice root in the oral preparation and detecting the content of paeoniflorin and berberine hydrochloride. The detection method is accurate and has high sensitivity, good repeatability and stable detection result, the quality of the medicinal oral preparation for treating irritable bowel syndrome can be effectively detected, and the standard of each detection item can guarantee the curative effect of the medicine.

Description

technical field [0001] The invention relates to a detection method of a drug for treating irritable bowel syndrome, which belongs to the field of pharmaceutical technology. Background technique [0002] Irritable bowel syndrome (IBS) is a group of continuous or intermittent episodes of functional gastrointestinal disorders characterized by abdominal pain, bloating, changes in bowel habits and / or stool properties. The causes of the disease are as follows: 1. Gastrointestinal motility disorder. 2. Abnormal visceral sensation. 3. Mental factors. 4. Intestinal infection. 5. Others, the symptoms of some IBS patients are related to food, and the disturbance of intestinal flora may also be one of the reasons for the symptoms. [0003] The clinical manifestations of irritable bowel syndrome are as follows: According to the main symptoms, it can be divided into: diarrhea-dominant type; constipation-dominant type; alternating diarrhea and constipation type. Abdominal pain is the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/90A61K36/752G01N30/02A61P1/00
CPCG01N30/02G01N30/90
Inventor 张永萍叶祖光徐剑刘耀
Owner 叶祖光