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Method for preparing medicine for treating infantile diarrhea

A technology for infantile diarrhea and drugs, applied in drug combinations, medical formulas, plant raw materials, etc., can solve the problems of lack of dialectics and outdated formulas, and achieve the effects of low cost, reduced osmotic pressure, and improved diet

Inactive Publication Date: 2015-02-18
樊金刚
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Traditional Chinese medicine prescriptions in the prior art lack dialectics, and the formulas are outdated. Finding effective and safe medicines from natural medicines has become an important direction for clinical infantile diarrhea

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A method for preparing a medicine for infantile diarrhea, the medicine is prepared from the following raw materials in parts by weight:

[0029] 25 parts of cloves, 25 parts of cinnamon, 25 parts of Chinese yam, 22 parts of barberry, 22 parts of poria cocos,

[0030] 20 parts of dandelion, 20 parts of grass fruit, 20 parts of big belly skin, 20 parts of hawthorn, 18 parts of dark plum,

[0031] 18 parts of astragalus, 15 parts of coix seed, 15 parts of papaya, 15 parts of malt, 15 parts of Moutan bark,

[0032] 15 parts of mint, 12 parts of licorice, 12 parts of tortoise shell, 12 parts of peach kernel, 10 parts of medlar,

[0033] 10 parts of amaranth, 10 parts of gardenia, 5 parts of almond, 5 parts of dried ginger, 5 parts of frankincense, and 5 parts of myrrh.

[0034] The preparation method of the medicine of the present invention is: get the raw material medicine preparation granule of above-mentioned parts by weight, concrete operation is:

[0035] 1) Take eac...

Embodiment 2

[0041] 1. Toxicity test

[0042]In this experiment, healthy SD rats were used, and the medicine prepared in Example 1 was administered orally for 30 days continuously. During the administration period of the rats and within 1 week after drug withdrawal, the animal growth status, activity diet, hematology, hematology, and so on were observed. There was no significant effect on chemistry, organ tissue structure and urine routine, indicating that the clinical medication is safe and reliable.

[0043] 2. Effects on castor oil-induced diarrhea model in mice

[0044] 60 ICR mice were randomly divided into control group, Smecta group and experimental (medicine in Example 1) group. The control group was given an equal volume of normal saline once a day for three consecutive days. 40 minutes after the last administration, each animal was given 0.2ml castor oil by intragastric administration. The mice were then placed in unit isolation cages with filter paper directly underneath, one ...

Embodiment 3

[0050] A total of 93 children with acute and chronic diarrhea were tested, including 47 females and 46 males, aged between half and three years old.

[0051] The above patients were randomly divided into two groups: 46 cases in the treatment group and 47 cases in the control group;

[0052] Diagnostic criteria

[0053] According to the diagnostic criteria for infantile diarrhea in the "Practical Pediatric Diagnosis and Treatment Standards", with pale tongue and white tongue coating as the main basis for the classification of spleen deficiency type, all patients were diagnosed as infantile diarrhea patients.

[0054] treatment method

[0055] The treatment group took the medicine prepared in Example 1 orally, 0.2g each time for <1 year old, 0.3g each time for 1-2 years old, and 0.5g each time for 2-3 years old, three times a day.

[0056] The control group took Smecta orally, 1 g each time for <1 year old, 2 g each time for 1-2 years old, and 3 g each time for 2-3 years old...

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Abstract

The invention relates to a preparation method of a medicinal preparation for treating infantile diarrhea. The medicinal preparation is prepared from the following raw materials: syzygium aromaticum, cortex cinnamomi, rhizoma dioscoreae, berberis thunbergii, poria cocos, dandelion, amomum tsao-ko, pericarpium arecae, fructus crataegi, dark plum, astragalus membranaceus, semen coicis, fructus chaenomelis lagenariae, malt, moutan bark, peppermint, liquorice, carapax eretmochelyos, peach kernel, the fruit of Chinese wolfberry, copperleaf herb, gardenia, apricot, rhizoma zingiberis, frankincense and myrrh. All the medicines are combined in use to bring out the best in each other, so the medicinal preparation is rapidly effective, safe and good in effect when being used for treating the infantile diarrhea.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a method for preparing medicines for treating infantile diarrhea. Background technique [0002] Infant diarrhea, also known as infant dyspepsia, is an acute gastrointestinal dysfunction in early childhood, a syndrome mainly characterized by diarrhea and vomiting, with the highest incidence in summer and autumn. The pathogenic factors of this disease are divided into three aspects: constitution, infection and digestive disorder. The main clinical manifestations are increased stool frequency, loose stools, and water and electrolyte disturbances. The disease is properly treated and the effect is good, but if it is not treated in time and severe water and electrolyte disorders occur, it may endanger the life of the child. At present clinical western medicine treatment is based on antiviral drugs, and its treatment measures mainly include: (1) trace...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/12
CPCA61K36/61A61K35/586A61K36/076A61K36/288A61K36/29A61K36/324A61K36/328A61K36/47A61K36/481A61K36/484A61K36/534A61K36/54A61K36/71A61K36/732A61K36/734A61K36/736A61K36/744A61K36/815A61K36/889A61K36/8945A61K36/8994A61K36/8998A61K36/9064A61K36/9068A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53
Inventor 樊金刚赵洪祥
Owner 樊金刚
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