Intestine-moistening bowel-relaxing medicinal preparation
A pharmaceutical preparation, laxative technology, applied in the field of medicine, to achieve the effect of controllable quality, stable preparation process and good reproducibility
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Embodiment 1
[0021] Example 1 The preparation of the ethanol extract of banana flower
[0022] Weigh 500g of dried jasmine flowers, mix them, pulverize them with a pulverizer, sieve them, add 8L of ethanol solution with a volume concentration of 70%, heat and decoct them, and extract them under reflux for 2 hours. Extract 3 times in total, combine the filtrates, and filter them with 4 layers of gauze , recover ethanol under reduced pressure until it has no alcohol smell, continue to concentrate, freeze-dry, pulverize, and pass through a 100-mesh sieve to obtain the alcohol extract of banana flower.
Embodiment 2
[0023] The preparation of embodiment 2 tablet
[0024] Alcoholic Extract of Banana Flower 100g
[0025] Lactose 120g
[0026] Microcrystalline Cellulose 60g
[0027] Sodium Carboxymethyl Cellulose 28g
[0028] Magnesium Stearate 3.2g
[0029] 50% ethanol appropriate amount
[0030] Preparation Process:
[0031] Mix the ethanol extract, lactose and microcrystalline cellulose passed through a 80-mesh sieve evenly, use an appropriate amount of 50% ethanol to make a soft material, pass through a 20-mesh sieve to granulate, blow dry at 60°C, and use a 20-mesh sieve Whole grains, then add the prescribed amount of sodium carboxymethylcellulose and magnesium stearate, mix and compress evenly, and make 500 tablets altogether. The tablet content specification is 200mg / tablet.
Embodiment 3
[0032] The preparation of embodiment 3 tablet
[0033] Alcoholic Extract of Banana Flower 50g
[0034] Mannitol 100g
[0035] Lactose 80g
[0036] Sodium carboxymethyl starch 8g
[0038] 8% starch slurry appropriate amount
[0039] Preparation Process:
[0040] Mix the ethanol extract of banana flower and auxiliary materials mannitol, lactose, and sodium carboxymethyl starch evenly, add an appropriate amount of starch slurry to make a soft material, and pass through a 16-mesh sieve to granulate. The wet granules are dried at 60°C, the dry granules are passed through a 16-mesh sieve for granulation, the fine powder in the dry granules is sifted out, mixed with magnesium stearate, and then mixed with the dry granules, and compressed into tablets to make 1000 tablets in total. The tablet content specification is 50mg / tablet.
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