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Intestine-moistening bowel-relaxing medicinal preparation

A pharmaceutical preparation, laxative technology, applied in the field of medicine, to achieve the effect of controllable quality, stable preparation process and good reproducibility

Inactive Publication Date: 2015-04-08
李健
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, as a traditional Chinese medicine, Zhujiaohua has been reported to have the effect of clearing away heat, resolving phlegm, cooling blood and stopping bleeding. Its extract has the effect of laxative or enhancing gastrointestinal peristalsis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1 The preparation of the ethanol extract of banana flower

[0022] Weigh 500g of dried jasmine flowers, mix them, pulverize them with a pulverizer, sieve them, add 8L of ethanol solution with a volume concentration of 70%, heat and decoct them, and extract them under reflux for 2 hours. Extract 3 times in total, combine the filtrates, and filter them with 4 layers of gauze , recover ethanol under reduced pressure until it has no alcohol smell, continue to concentrate, freeze-dry, pulverize, and pass through a 100-mesh sieve to obtain the alcohol extract of banana flower.

Embodiment 2

[0023] The preparation of embodiment 2 tablet

[0024] Alcoholic Extract of Banana Flower 100g

[0025] Lactose 120g

[0026] Microcrystalline Cellulose 60g

[0027] Sodium Carboxymethyl Cellulose 28g

[0028] Magnesium Stearate 3.2g

[0029] 50% ethanol appropriate amount

[0030] Preparation Process:

[0031] Mix the ethanol extract, lactose and microcrystalline cellulose passed through a 80-mesh sieve evenly, use an appropriate amount of 50% ethanol to make a soft material, pass through a 20-mesh sieve to granulate, blow dry at 60°C, and use a 20-mesh sieve Whole grains, then add the prescribed amount of sodium carboxymethylcellulose and magnesium stearate, mix and compress evenly, and make 500 tablets altogether. The tablet content specification is 200mg / tablet.

Embodiment 3

[0032] The preparation of embodiment 3 tablet

[0033] Alcoholic Extract of Banana Flower 50g

[0034] Mannitol 100g

[0035] Lactose 80g

[0036] Sodium carboxymethyl starch 8g

[0037] Magnesium Stearate 2g

[0038] 8% starch slurry appropriate amount

[0039] Preparation Process:

[0040] Mix the ethanol extract of banana flower and auxiliary materials mannitol, lactose, and sodium carboxymethyl starch evenly, add an appropriate amount of starch slurry to make a soft material, and pass through a 16-mesh sieve to granulate. The wet granules are dried at 60°C, the dry granules are passed through a 16-mesh sieve for granulation, the fine powder in the dry granules is sifted out, mixed with magnesium stearate, and then mixed with the dry granules, and compressed into tablets to make 1000 tablets in total. The tablet content specification is 50mg / tablet.

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PUM

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Abstract

The invention discloses an intestine-moistening bowel-relaxing medicinal preparation. The preparation is prepared from an active composition and pharmaceutically-acceptable auxiliary materials, and the active composition is alcohol extractive of cordyline fruticosa. Compared with the prior art, the medicinal preparation is prepared by taking cordyline fruticosa as the only raw material, is good in intestine-moistening bowel-relaxing effect, low in toxic and side effects and high in safety, is applicable to treat constipation patients caused by accumulation of dry feces and water shortage, and is capable of moistening intestine and relaxing bowel, discharging toxin and nourishing skin.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical preparation, which can moisten intestines and laxatives, discharge toxins and nourish skin. Background technique [0002] With the acceleration of the pace of modern life, the increase of work pressure, the aging of society, the change of eating habits, and the change of disease spectrum, etc., constipation has become one of the important factors affecting the quality of life of modern people. The incidence of colorectal cancer is closely related. Constipation refers to dry, hard, infrequent or difficult defecation, mostly due to insufficient food and water intake, improper feeding, or sudden changes in eating habits and other factors. [0003] Modern medicine has gradually perfected the concept, classification, types of drugs and surgical treatment of constipation, which has promoted the rational understanding of the diagnosis and treatment of cons...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A23L1/29A61P1/10A61P1/14A23L33/00
Inventor 李健
Owner 李健
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