Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of prinsepiautilis Royle tender bud extractive to whitening product and whitening product

A green thorn point and extract technology, which is applied in the field of green thorn point extract, can solve problems such as safety, component instability, application restrictions, etc., and achieve good safety, prominent whitening effect, and high safety effect

Active Publication Date: 2015-04-22
俞文洁
View PDF1 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, their applications are limited due to problems such as insufficient skin whitening effect, safety issues on the skin, and instability of ingredients when used in cosmetics.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of prinsepiautilis Royle tender bud extractive to whitening product and whitening product
  • Application of prinsepiautilis Royle tender bud extractive to whitening product and whitening product
  • Application of prinsepiautilis Royle tender bud extractive to whitening product and whitening product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: the preparation of green thorn point extract

[0033] Take 2 kg of green thorn tips (the green thorn tips are collected from Lijiang, Yunnan, and dried in the sun), crush them, soak them in 20 liters of 70% ethanol at room temperature for one day, and extract them under reflux for 60 minutes. After filtering out the extract, add 16 liters of 70% ethanol, reflux extraction for 40 minutes, and filter. The two extracts were combined and concentrated to dryness in vacuo to obtain 360 g of Punjabis punctatus primary extract (codenamed PUE), with a yield of 18%.

Embodiment 2

[0034] Embodiment 2: the preparation of green thorn point polyphenol

[0035] Get the first extract 100g of the green thorn tip prepared in Example 1, add water to dissolve, and carry out chromatography on AB-8 macroporous adsorption resin. The ratio of the amount of extract to the weight of resin is about 1:20. Sequentially eluted with water, 30% ethanol, 60% ethanol and 95% ethanol, each gradient eluted with 4-5 column volumes, and the flow rate was 2-3 column volumes / hour. After the elution, the 30% ethanol part (PU30), the 60% ethanol part (PU60) and the 95% ethanol part (PU95) were concentrated to dryness respectively, of which the 30% ethanol part was 20g in total, the 60% ethanol part was 43g in total, 95 A total of 15g of % ethanol parts.

Embodiment 3

[0036] Example 3: Isolation and structural identification of green thorn tip whitening active compound

[0037] Take 30 g of the 60% ethanol part in Example 2, go to silica gel column chromatography, and use chloroform: the volume ratio of methanol is respectively 20:1, 15:1, 10:1, 5:1, and 1:1 to carry out gradient washing Take off, get 5 parts respectively. Chloroform:methanol ratio 5:1 eluted part was then chromatographed with C18 reverse-phase preparative column, gradient elution was carried out with 20% methanol, 40% methanol, 60% methanol, 90% methanol, and 40% methanol The eluted part was subjected to Sephadex LH-20 gel column chromatography and eluted with 100% ethanol to obtain compound 1, whose structure was identified by physical and chemical constants and modern spectroscopy means (MS, NMR).

[0038]Compound 1: Pale yellow powder, ESI-MS gives the molecular ion peak as m / z: 413[M+Na]+, combined with hydrogen and carbon spectrum to determine the molecular formula i...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to application of prinsepiautilis Royle tender bud extractive to a whitening product and the whitening product containing prinsepiautilis Royle tender bud extractive and / or prinsepiol. Polyphenols in the prinsepiautilis Royle tender bud extractive are a kind of new whitening active compositions, have obvious effects of inhibiting tyrosinase activity and reducing melanin generated by B16 melanocyte, and also the whitening active compositions come from plant, and therefore the prinsepiautilis Royle tender bud extractive is good in safety, and has extremely high feasibility of developing external-use medicines or beautifying cosmetics for whitening, spot removing and the like.

Description

technical field [0001] The invention relates to a new application of the green thorn extract and a whitening product. Background technique [0002] In recent years, due to the increase in people's stress and the increase in intake of high-calorie, high-protein, and high-fat foods, the color of human skin is determined by many factors, including the activity of melanocytes (melanocytes) that produce melanin, the blood vessels. distribution, thickness of the skin, presence or absence of pigments such as carotenoids and bilirubin, etc. Among these factors, the dark pigment melanin is the most important factor. Melanin is produced by melanocytes through the action of various enzymes including tyrosinase. The production of melanin is influenced by genetic factors, physiological factors such as hormone secretion, stress, etc., and environmental factors such as UV radiation. Melanin present in the skin plays an important role in protecting the skin from stimuli such as UV rays. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K8/97A61K8/49A61K36/73A61Q19/02A61Q19/00A61P17/00
Inventor 俞文洁张良诚
Owner 俞文洁
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com