Traditional Chinese medicine preparation for treating contrast-induced nephropathy

A traditional Chinese medicine preparation and technology of traditional Chinese medicine, which are applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, can solve the problems of easy recurrence, the inability to effectively popularize dialysis, and the inability to effectively control the disease, and achieve the effect of exact curative effect.

Inactive Publication Date: 2015-04-29
WEIFANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When drug treatment is ineffective, dialysis therapy is used as the main measure of rescue, but the above-mentioned drug treatment methods often have relatively large toxic and side effects on the patient's kidney organs, and are likely to cause drug dependence in the patient, and are prone to relapse, and cannot effectively control the disease. Due to technical and other reasons, dialysis cannot be effectively popularized

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Example 1: A traditional Chinese medicine preparation for the treatment of acute contrast-induced nephropathy, selecting 20 grams of rhubarb, 10 grams of Glauber's salt, 10 grams of cassia twig, 10 grams of poria cocos, 10 grams of safflower, 10 grams of large thistle, 10 grams of small thistle, buffalo horn 10 grams, 10 grams of peach kernel, 8 grams of Ophiopogon japonicus, 8 grams of ginseng, 8 grams of Uncaria, 8 grams of fresh ground, 8 grams of Tinglizi, 8 grams of Magnolia officinalis, 8 grams of Mutong, 8 grams of Cortex Phellodendri, 8 grams of lotus root .

Embodiment 2

[0061] Embodiment 2: A kind of traditional Chinese medicine preparation for the treatment of acute contrast nephropathy, choose rhubarb 25 grams, Glauber's salt 15 grams, cassia twig 15 grams, Poria cocos 15 grams, safflower 15 grams, big thistle 15 grams, small thistle 15 grams, buffalo horn 15 grams, 15 grams of peach kernel, 12 grams of Ophiopogon japonicus, 10 grams of ginseng, 10 grams of Uncaria, 10 grams of fresh ground, 10 grams of Tinglizi, 10 grams of Magnolia officinalis, 10 grams of Akebia, 10 grams of Cortex Phellodendri, 10 grams of lotus root .

Embodiment 3

[0062] Embodiment 3: A kind of traditional Chinese medicine preparation for the treatment of acute contrast nephropathy, choose rhubarb 30 grams, Glauber's salt 20 grams, cassia twig 20 grams, Poria cocos 20 grams, safflower 20 grams, large thistle 20 grams, small thistle 20 grams, buffalo horn 20 grams, 20 grams of peach kernels, 15 grams of Ophiopogon japonicus, 12 grams of ginseng, 12 grams of Uncaria, 12 grams of fresh ground, 12 grams of Tinglizi, 12 grams of Magnolia officinalis, 12 grams of Mutong, 12 grams of Cortex Phellodendri, 12 grams of lotus root .

[0063] Chinese medicine preparation curative effect of the present invention is further verified by concrete case below:

[0064] Case 1

[0065] Wang, female, 36 years old. Abdomen-enhanced CT examination was performed due to liver lesions. After injecting 80ml of contrast medium, symptoms such as nausea, vomiting, and body length jaundice appeared. Hospital examination revealed that blood potassium was 5.0mmol / L,...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating contrast-induced nephropathy. The traditional Chinese medicine preparation comprises the following selected raw material medicines by weight: 20-30g of rheum officinale, 10-20g of mirabilite, 10-20g of cassia twig, 10-20g of poria cocos, 10-20g of safflower carthamus, 10-20g of circium japonicum, 10-20g of field thistle, 10-20g of cornu bubali, 10-20g of peach kernels, 8-15g of radix ophiopogonis, 8-12g of ginseng, 8-12g of uncaria, 8-12g of fresh radix rehmanniae recen, 8-12g of semen lepidii, 8-12g of mangnolia officinalis, 8-12g of akebiaquinata, 8-12g of golden cypress and 8-12g of rhizoma nelumbinis, wherein the medicines are excellent in compatibility and reasonable in formula, and co-exert the effects of nourishing yin to lessen fire, purging turbidity and detoxifying, cooling blood and dispersing stasis, and tonifying qi and promoting urination; the efficacy eliminates evil without injuring vital energy, and plays the roles of 'opening top', 'smoothing middle' and 'permeating bottom', thus the water channels of the triple energizers are smoothed, and the gasification of the lungs, spleen and kidneys are recovered, then urination is normal, edema is eliminated, and various diseases are treated.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine preparation capable of treating abnormal renal function caused by application of contrast agents. Background technique [0002] Contrast-induced nephropathy (CIN) is an important complication in the application of iodine contrast agent and an important part of iatrogenic renal failure. It is not only unfavorable to the clinical prognosis of patients, but also increases the medical expenses of patients . As the number of patients undergoing contrast examinations and interventional procedures continues to increase, more patients are receiving iodine contrast agents. Therefore, contrast-induced nephropathy has become a common concern of radiologists, cardiologists and nephrologists. [0003] Contrast-induced nephropathy is defined as the serum creatinine level increases within 24 hours after the application of iodine contrast me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61P13/12A61K35/32A61K33/04
CPCA61K36/708A61K9/0095A61K33/04A61K35/32A61K36/076A61K36/185A61K36/258A61K36/28A61K36/286A61K36/31A61K36/54A61K36/575A61K36/62A61K36/736A61K36/74A61K36/756A61K36/804A61K36/8968A61K2300/00
Inventor 岳奎涛
Owner WEIFANG MEDICAL UNIV
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