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Use of traditional Chinese medicine preparation in preparation of medicine for treating diarrhea after chemotherapy

A technology of traditional Chinese medicine preparations and uses, which is applied in the field of preparation of drugs for treating diarrhea after chemotherapy, and in the field of traditional Chinese medicine preparations, which can solve problems such as fundamentally regulating gastrointestinal function, reducing patient compliance, and serum electrolyte disturbance, so as to improve acceptance and medication compliance Sexuality, significant synergistic effect, adverse reaction and side effect reduction effect

Inactive Publication Date: 2015-04-29
DONGGUAN ZHIJIAN MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chemotherapy-associated diarrhea can not only make patients weak, dehydrated, renal failure, serum electrolyte disturbance, acid-base balance disorder, severe diarrhea can delay treatment, reduce patient compliance, and even endanger life, leading to interruption of chemotherapy
There is no satisfactory treatment plan for this in the world, and most of them are passive symptomatic treatment mainly for antidiarrheal, without fundamentally regulating gastrointestinal function, which has become a difficult point in clinical treatment

Method used

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  • Use of traditional Chinese medicine preparation in preparation of medicine for treating diarrhea after chemotherapy
  • Use of traditional Chinese medicine preparation in preparation of medicine for treating diarrhea after chemotherapy

Examples

Experimental program
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Effect test

Embodiment 1

[0065] Step (1), accurately weighed according to the Chinese medicine prescription of the present invention: Poria 1500g, Atractylodes macrocephala 1100g, Atractylodes atractylodes 500g, Magnolia officinalis 1200g, Chenpi 1300g, Amomum 500g, Cimicifuga 1000g, Schisandra 1100g, Bupleurum 1000g, dried ginger 1200g, Cinnamon sticks 500g, cumin 900g, corydalis 1200g, oyster 1200g, jujube 1600g, white peony root 900g, Cyperus cyperi 1100g, licorice 2000g, crushed separately and mixed;

[0066] Step (2), add 10 times the weight of purified water, soak for 10 hours, reflux and decoct for 3 hours, and filter to obtain the filtrate; add purified water of 6 times the weight of the initial medicinal material to the filter residue, reflux and decoct for 2 hours, and filter to obtain the filtrate; Add purified water 5 times the weight of the original medicinal material to the filter residue, reflux and decoct for 1 hour, and filter to obtain the filtrate; mix the 3 times of filtrate and con...

Embodiment 2

[0069] Step (1), accurately weighed according to the Chinese medicine prescription of the present invention: Poria cocos 3200g, Atractylodes macrocephala 2400g, atractylodes rhizome 1600g, Magnolia officinalis 2400g, tangerine peel 2600g, Amomum 1200g, Cimicifuga 2000g, Schisandra 1700g, Bupleurum 2200g, dried ginger 2600g, Cinnamon sticks 1300g, fennel 1700g, Corydalis 3000g, oyster 2800g, jujube 3200g, white peony 1900g, Cyperus cyperi 2300g, licorice 3000g, crushed separately and mixed;

[0070] Step (2), add 10 times the weight of purified water, soak for 10 hours, reflux and decoct for 3 hours, and filter to obtain the filtrate; add purified water of 6 times the weight of the initial medicinal material to the filter residue, reflux and decoct for 2 hours, and filter to obtain the filtrate; Add purified water 5 times the weight of the original medicinal material to the filter residue, reflux and decoct for 1 hour, and filter to obtain the filtrate; mix the 3 times of filtra...

Embodiment 3

[0073] Step (1), accurately weighed according to the Chinese medicine prescription of the present invention: Poria cocos 24kg, Atractylodes macrocephala 20kg, Atractylodes atractylodes 13kg, Magnolia officinalis 22kg, Chenpi 25kg, Amomum 8kg, Cimicifuga 16kg, Schisandra 15kg, Bupleurum 18kg, dried ginger 22kg, Cinnamon 8kg, Cumin 14kg, Corydalis 25kg, Oyster 24kg, Jujube 29kg, Radix Paeoniae Alba 14kg, Cyperus cyperi 17kg, Licorice 25kg, crushed separately and mixed;

[0074] Step (2), add 10 times the weight of purified water, soak for 10 hours, reflux and decoct for 3 hours, and filter to obtain the filtrate; add purified water of 6 times the weight of the initial medicinal material to the filter residue, reflux and decoct for 2 hours, and filter to obtain the filtrate; Add purified water 5 times the weight of the original medicinal material to the filter residue, reflux and decoct for 1 hour, and filter to obtain the filtrate; mix the 3 times of filtrate and concentrate unde...

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Abstract

The invention relates to the use of a traditional Chinese medicine preparation in the preparation of a medicine for treating diarrhea after chemotherapy. The traditional Chinese medicine preparation is a finished traditional Chinese medicine preparation product which is convenient and easy to use and is prepared from the traditional Chinese medicinal materials: poria cocos, rhizoma atractylodis macrocephalae, rhizoma atractylodis, magnolia officinalis, dried orange peel, fructus amomi, rhizoma cimicifugae, schisandra chinensis, radix bupleuri, dried ginger, cassia twig, common fennel, rhizoma corydalis, oyster, fructus jujubae, radix paeoniae alba, cyperus rotundus and radix liquiritiae through a special preparation process. In terms of treatment of the diarrhea caused by cancer chemotherapy, the preparation has the technical advantages that the efficiency is high, both symptoms and root causes are treated, nursing is emphasized, and toxic and side effects are avoided; moreover, the operation process is simple and convenient, the medicine effect is stable, and the traditional Chinese medicine preparation is easy to popularize and apply.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to the use of a traditional Chinese medicine preparation in preparing medicines for treating post-chemotherapy diarrhea. Background technique [0002] Cancer, also known as malignancy, is a disease caused by abnormalities in the mechanisms controlling cell growth and proliferation. In addition to growing out of control, cancer cells can also locally invade the surrounding normal tissues and even transfer to other parts of the body through the internal circulatory system or lymphatic system. Cancer has become a major killer facing human beings, and its mortality rate is second only to cardiovascular diseases, and it is increasing year by year. There are 1.8 million malignant tumor patients in my country every year, and 2 / 3 of them receive chemotherapy. [0003] Chemotherapy is one of the main methods for the clinical treatment of malignant tumors today, but ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P1/12A61K35/618
CPCA61K36/076A61K9/0095A61K35/618A61K36/23A61K36/233A61K36/284A61K36/484A61K36/54A61K36/57A61K36/575A61K36/65A61K36/66A61K36/71A61K36/725A61K36/752A61K36/79A61K36/8905A61K36/9064A61K36/9068A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 刘永红
Owner DONGGUAN ZHIJIAN MEDICAL TECH