Diazepam composition freeze-dried tablet and preparation method thereof

A composition and freeze-dried tablet technology, applied in the field of diazepam composition freeze-dried tablet and its preparation, to achieve the effects of good formability, improved dissolution and improved adhesion
CN104586793AInactive Publication Date: 2015-05-06HAINAN WEI KANG PHARMA QIANSHAN
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HAINAN WEI KANG PHARMA QIANSHAN
Publication Date
2015-05-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a diazepam composition freeze-dried tablet and a preparation method thereof, and relates to the technical field of medicines and medicine production. The diazepam composition freeze-dried tablet comprises diazepam, starch and cane sugar; the starch and the cane sugar are used as auxiliary materials, and common corn starch is heated, so that the adhesion and disintegration functions of the starch in the tablet can be improved, the formability of the tablet is improved; the diazepam composition freeze-dried tablet only needs two auxiliary materials: the starch and the cane sugar. The diazepam composition freeze-dried tablet adopts a freeze-drying process of cooling for twice and heating for twice, the formability of the tablet is better, the dissolution rate of the tablet is improved and the bioavailability of the tablet is improved; the tablet has the advantages of overcoming the defects of the common diazepam tablet and decreasing the kinds and dosage of the auxiliary materials in the diazepam tablet, is large in dissolution rate and high in bioavailability and ensures the curative effect and safety of clinic medication.
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Description

technical field

[0001] The invention relates to the technical field of medicine and medicine production, in particular to a freeze-dried tablet of a diazepam composition and a preparation method thereof. Background technique

[0002] Diazepam is a benzodiazepine drug, a central depressant, with good anxiolytic, sedative, hypnotic, anticonvulsant and muscle relaxant effects. Its stability, muscle relaxation and anticonvulsant effects are stronger than chlordiazepoxide, and can indirectly expand arterioles and veins, reduce peripheral vascular resistance, increase coronary blood flow, decrease left ventricular end-diastolic pressure, and reduce oxygen consumption.

[0003]

[0004] Ordinary diazepam tablets contain many types and quantities of excipients. Generally, fillers, lubricants, disintegrants, binders, flavoring agents, etc. are used. According to the second part of the Chinese Pharmacopoeia (2010 edition), diazepam According to the quality standard of Panpan Table...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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