Antiasthma particles and preparation method thereof

A granule and asthma-relieving technology, applied in the field of Pingchuan granules and its preparation, can solve the problems of low utilization rate of Tianshan Rowan resources, poor patient compliance, bitter taste of asthma, etc., and achieves reduction in the amount of raw medicinal materials and good patient compliance. , the effect of reducing production costs

Inactive Publication Date: 2015-06-17
XINJIANG MEDICAL UNIV
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention provides a kind of antiasthma granule and its preparation method, which overcomes the deficiencies of the above-mentioned prior art, and can effectively solve the problem of existing Tianshan Sorbus extract powder The content of total flavonoids is low, the production cost is high, and the resource utilization rate of Tianshan Sorbus is low; the medicine obtained for treating asthma has a bitter taste, extremely poor taste and difficulty in swallowing, which leads to poor patient compliance

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Antiasthma particles and preparation method thereof
  • Antiasthma particles and preparation method thereof
  • Antiasthma particles and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1, the Pingchuan granules are obtained according to the following preparation method: the first step, the branches and leaves of Sorbus tianshanensis and the fruit of Sorbus tianshanensis are mixed at a mass ratio of 7:3, and the mixed medicinal materials are obtained after pulverization; the second step is mixed medicinal materials and 50% ethanol aqueous solution by volume percentage is 1:18, adding 50% ethanol aqueous solution to the mixed medicinal materials for extraction 3 times, the time of each extraction is 2h to 3h, and the temperature of each extraction The temperature is 80°C to 95°C. After each extraction is completed, the extract is obtained by filtration, and the extracts obtained each time are combined to obtain a blended liquid; the third step is to concentrate the blended liquid to 15% to 20% of the volume of the blended liquid Finally, the concentrated solution is obtained. At a temperature of 40°C to 50°C, add a clarifying agent of 8% of the...

Embodiment 2

[0022] Example 2, the Pingchuan granules are obtained according to the following preparation method: the first step, the branches and leaves of Sorbus tianshanensis and the fruit of Sorbus tianshanensis are mixed at a mass ratio of 7:3, and the mixed medicinal materials are obtained after pulverization; the second step is mixed medicinal materials And volume percentage is 50% ethanol water solution according to mass ratio is 1:18, add volume percentage in mixed medicinal material and be 50% ethanol water solution extraction 3 times, the time of each extraction is 2h or 3h, the temperature of each extraction The temperature is 80°C or 95°C. After each extraction is completed, the extract is obtained by filtration, and the extracts obtained each time are combined to obtain a blended liquid; the third step is to concentrate the blended liquid to 15% or 20% of the volume of the blended liquid Finally, the concentrated solution is obtained. At a temperature of 40°C to 50°C, add a c...

Embodiment 3

[0023] Embodiment 3, as the optimization of above-mentioned embodiment, clarification agent is the chitosan solution of 1%, and the chitosan solution of 1% is obtained as follows: get 1mL glacial acetic acid, add distilled water and dilute to 50mL, add 1.0g shell The polysaccharide was mixed evenly, and distilled water was added to make the volume to 100mL and mixed evenly. After swelling for 24 hours, a 1% chitosan solution was obtained.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
particle size (mesh)aaaaaaaaaa
particle sizeaaaaaaaaaa
Login to view more

Abstract

The invention relates to the technical field of medicines for treating asthma, and provides antiasthma particles and a preparation method thereof. Compared with the sorbus tianshanica extract powder, the sorbus tianshanica extract powder in the invention is greatly improved in the total flavonoid content, ratio of extraction and total flavone transfer rate, the quantity of sorbus tianshanica crude medicine is greatly reduced, the crude medicine use rate is improved, the ethnic drug resources are reasonably utilized. Through adding a clarifying agent, pollution of impurities to resin is reduced, the reuse ratio of resin is improved, and the production cost is reduced; and besides, through adding the aspartame, the bitter taste of the sorbus tianshanica extract powder is better covered; the antiasthma particles obtained and provided by the invention are equivalent to drugs for treating asthma in the prior art in the antiasthma effect, is good in taste, better in patient compliance, easy to take and suitable for industrial production.

Description

technical field [0001] The invention relates to the technical field of medicines for treating asthma, and relates to an asthma granule and a preparation method thereof. Background technique [0002] Asthma is a chronic airway inflammatory disease involving a variety of cells, including airway inflammatory cells, cell components and structural cells. At present, the recognized pathological concept of asthma in the medical field is repeated exacerbation of chronic airway inflammation, and the pathological phenomenon of airway remodeling induced by chronic airway inflammation is proposed. Asthma has a long onset period and is easy to relapse. If a severe acute attack occurs, it may be fatal if it is not treated in time. Patients with poorly controlled asthma will have an impact on their daily work and life, resulting in missed work, missed studies, limited exercise, reduced quality of life, and a huge economic burden, which greatly affects the normal work and life of the patie...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61K9/16A61P11/06
Inventor 常军民向阳马迪李改茹孙红艳
Owner XINJIANG MEDICAL UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap