33results about How to "Improve the paste rate" patented technology

The present invention provides a scutellaria baicalensis extract preparation method, wherein scutellaria baicalensis is adopted as a raw material, weak acid ethanol reflux extraction is performed, and one-step acid precipitation and macroporous resin separation and purification are combined to prepare the scutellaria baicalensis extract. According to the present invention, the weak acid ethanol is used to extract, such that the active ingredients in the herb are subjected to complete dissolution and are utilized to the greatest degree; the extraction solution si directly used for acid precipitation without concentration, the purity of the scutellaria baicalensis in the obtained precipitate is high, and the recovered ethanol solvent is the acid ethanol after the acid precipitation so as to be continuously used for the extraction to form the closed loop, such that the acid-free emission is achieved; the purified product has the high recovery rate and the high purity, and the purity of the scutellaria baicalensis in the final product is more than or equal to 95%; and the operation is simple, the process is safe and easy to operate, the two-step acid adjusting method in the current process is avoided, the environmental pollution is reduced, the repeatability is high, the operability is strong, and the method is suitable for industrial production.

The invention relates to a health-care product, in particular to a muscle and joint-innerve spraying agent. The invention also relates to a preparation method. Pre 1000 ml muscle and joint-innerve spraying agent is made by the active pharmaceutical ingredient and accessories in the following weight ratio, wherein, the active pharmaceutical ingredient is that: clematis root 50 to 60 g, safflower 5 to 13 g, leech 20 to 35 g, dragon's blood 40 to 50 g, olibanum 10 to 20 g, myrrh 10 to 20 g, monkshood root 15 to 25 g, barrenwort 40 to 60 g, borneol 5 to 12 g, propolis 20 to 30 g, laurocapram 8 to 12g and ethyl fiber 2 to 4 g. the invention is suitable for people with pain caused by cervical spondylosis, scapulahumeral periarthritis, protrusion of lumbar intervertebral discs, osteoarthritis, gout and herpes zoster, and people suffering from lumbocrural pain, muscle soreness and neurogenic headache. The health-care product has the advantages of releasing pain and improving microcirculation.

The invention relates to the field of traditional Chinese medicine modernization, in particular to a preparation method and a detection method of a fructus psoraleae standard decoction. The preparation method of the fructus psoraleae standard decoction comprises the following steps: decocting fructus Psoraleae medicinal materials with water, and filtering to obtain filtrate; concentrating and drying the filtrate, and then performing lyophilization which is divided into three stages: a. pre-freezing at the pre-freezing temperature of -50 DEG C to -45 DEG C; b. primary drying at the drying temperature of -30 DEG C to 0 DEG C; and c. secondary drying at the drying temperature of 5 DEG C to 25 DEG C, so as to obtain the fructus Psoraleae standard decoction. The preparation method of the invention has the beneficial effects that: the fructus psoraleae standard decoction has high paste yield, and has relatively stable content, relatively stable water content, moisture absorption resistance,and no impurity component through a 6-month accelerated stability test. The invention provides a method for measuring the total content and the total transfer rate of psoralen and isopsoralen, which has good specificity, good repeatability and good stability. A characteristic spectrum method of the invention adopts the ultra-high phase liquid phase, is simple, can greatly shorten the detection time and improve the production efficiency.

The invention discloses an extraction method for salidroside. The extraction method comprises the following steps: obtaining a crushed rhodiola rosea material, and carrying out enzymolysis so as to obtain an enzymatic hydrolysate; adding the enzymatic hydrolysate into an extraction tank in batches so as to obtain a crude rhodiola rosea extract; and purifying the crude rhodiola rosea extract so asto obtain the salidroside; wherein the treatment method for each batch of the enzymatic hydrolysate comprises the following steps: adding water, and carrying out stirring at 35-45 DEG C; adding waterinto a system, and carrying out heating to 55-65 DEG C; adding water into the system, carrying out heating to 75-85 DEG C, and carrying out stirring; adding water into the system, and carrying out stirring; reducing the temperature of the system to 55-65 DEG C so as to obtain filtering residues and a primary extracting solution; and washing the filtering residues of the system with water, carryingout filtering so as to obtain a secondary extracting solution, and combining the primary extracting solution and the secondary extracting solution so as to obtain the crude rhodiola rosea extract. According to the invention, the rhodiola rosea is firstly subjected to enzymolysis after being crushed, and the enzymatic hydrolysate is subjected to extraction in batches at different temperatures, sothe transfer rate of the salidroside can be effectively increased, and the extraction rate of the salidroside is increased.

The invention discloses a preparation method of Chinese medicine extract for relieving superficies. The preparation method comprises the following steps: weighing the raw medicine according to the ratio, adding water for soaking, steaming the raw medicine, collecting the water vapor, the mother liquor and the filter residue containing the raw medicine components from the raw medicine, cooling the collected water vapor, the mother liquor and the filter residue for decoction and combination with the water vapor coolant to obtain the combined liquid. The combined liquid is washed with ethanol, stirred, and allowed to stand overnight. After filtration, the ethanol is recovered under reduced pressure and then concentrated to relative density of 1.10-1. 35 of the cream. The traditional Chinese medicine extract prepared by the invention can obviously improve the content of the active ingredient and improve the therapeutic effect of the prescription.

The invention provides a novel solid paste formula and a preparation method thereof. The preparation method includes the following steps: S1, pulverizing raw materials into 60-200 mesh, and mixing with water according to the mass ratio of 1 to (15-30), to obtain a mixed solution; S2, wall-breaking the mixed solution, and filtering to remove residues, to obtain an extraction solution; S3, filteringand purifying the extraction solution by microfiltration, ultrafiltration and nanofiltration in turn, to obtain a filtrate; and S4, under the conditions of negative pressure and the temperature of 25-30 DEG C, dehydrating the filtrate obtained by the S3, controlling the water content to 3% or less, and thus obtaining the solid paste formula. The preparation method solves the problem of active ingredient deactivation caused by high-temperature repeated decoction of a conventional solid paste formula, has low energy consumption, greatly shortens the production time, and can improve the paste production rate of the solid paste formula. The obtained solid paste formula crystal has the advantages of standard quantization, convenient carrying, taking at any time, good experience feeling and high safety while intactly retaining the comprehensive effect of nourishment tonifying and treatment prevention of a classic paste formula.

The invention discloses a method for preparing a phellinus igniarius extract through micromolecule water and an application. The method comprises the following steps of crushing phellinus igniarius, performing screening to obtain phellinus igniarius powder, sequentially adding the micromolecule water, enzymes and the phellinus igniarius powder to a container, and performing homogenizing, stirringand mixing so as to obtain mixed liquor; placing the mixed liquor in supercritical water reaction kettle, introducing reaction products into a condenser for condensing, and performing pressure filtration on the reaction products in a collector so as to obtain filtrate and filter residues; mixing the filter residues with the micromolecule water, then performing bifrequency ultrasonic extraction, filtering the extracted blending liquor by a centrifugal method so as to obtain filtrate and filter residues; mixing the filter residues with the micromolecule water, performing soxhlet extraction, andthen performing solid-liquid separation so as to obtain filter residues and filtrate; and mixing the separated filtrate, performing concentration on the mixed filtrate, and performing vacuum drying soas to obtain the phellinus igniarius composite extract. The phellinus igniarius composite extract is high in cream yield rate, the purity of effective components in the extract is high, and the utilization rate of the phellinus igniarius is effectively increased.

The invention relates to the technical field of traditional Chinese medicine extraction, and discloses a preparation method of a fructus cannabis extract. The preparation method comprises the following steps: preparing fructus cannabis decoction pieces into coarsest powder, putting the coarsest powder and water with the weight being 6-12 times that of the coarsest powder into an extraction tank, adding beta cyclodextrin with the weight being 2-10% of that of the coarsest powder of fructus cannabis into water with the weight being 5-20 times that of the coarsest powder of fructus cannabis to prepare a beta cyclodextrin solution, dynamically stirring, keeping micro-boiling decoction for 0.5-3h, and filtering to obtain a first extracting solution and medicine residues; putting the medicine residues and water with the weight being 5-12 times that of the coarsest powder of fructus cannabis into the extraction tank, dynamically stirring, keeping micro-boiling decoction for 0.5-3h, and filtering to obtain a second extracting solution; combining the two extracting solutions, and centrifuging to obtain a centrifugate; and carrying out low-temperature reduced pressure concentration on the centrifugate until the relative density is 1.05-1.15, measuring the relative density at 60 DEG C, and carrying out spray drying or belt drying to obtain the fructus cannabis extract. According to the preparation method, water-soluble substances of fructus cannabis can be effectively extracted, and fat-soluble components can be effectively extracted, so that a complex process of oil pressing and theninclusion is avoided, and the process is effective, simple and feasible and is suitable for large-scale production.

The invention relates to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a preparation process of compound glabrous greenbrier rhizome granules. According to the preparation process provided by the invention, a water extraction process is optimized, so that the extraction ratio of the water extraction process is greatly improved; a ZTC1+1-II type natural clarifying agent is adopted in a clarifying process and is used for replacing ethyl alcohol in a water extract and alcohol precipitation process of Chinese herbal medicine preparation, so that the traditional water extract and alcohol precipitation process is simplified, the production period is shortened and the cost is lowered but also the clarifying efficiency is improved and the good repeatability of a granule forming process is realized. Thus, the production cost is lowered. Compared with the granules prepared by using the existing technology, the compound glabrous greenbrier rhizome granules obtained by using the preparation process provided by the invention are high in extract yield, high in effective ingredient content, low in hygroscopicity and high in stability.

The invention relates to an extraction process of a plant rumex gmelini and an extract thereof. The extraction steps are as follows: 1. The dried root of rumex gmelini is grinded into initial powder, and a certain weight amount of which is added into a Soxhlet extractor. 2. The initial powder in the Soxhlet extractor is constantly refluxed and extracted for 4h by 70ml of ethanol (50 percent) in the temperature of keeping the liquid boiling slightly. 3. The extract is filtered after cooling and is dried by distillation under normal pressure and at the temperature of 50 to 60 DEG C. 4. The acquired dry paste is crushed into powder by a conventional method, thus acquiring the rumex gmelini extract.

The invention belongs to the technical field of extraction of plants, in particular to an extraction method of gastrodin in wild rhizoma gastrodiae. The extraction method disclosed by the invention has the advantages that extraction of the gastrodin in the wild rhizoma gastrodiae with high content of the gastrodin is carried out, and because the wild rhizoma gastrodiae contains more medicinal ingredients, that is, gastrodin and gastrodioside citronellol, a flavor of the rhizoma gastrodiae planted through artificial cultivation cannot be compatible with the special flavor of the wild rhizoma gastrodiae; specially on the long lasting of the smell, after common rhizoma gastrodiae is put on a counter, people basically cannot smell the scent, on the contrary, the wild rhizoma gastrodiae is different, even the wild rhizoma gastrodiae is dried for a period of time, the smell can keep lasting for long time and cannot fade away, so the the extraction quantity of the gastrodin ensured; and meanwhile, through proportioning of ethanol solutions with appropriate concentration, the gastrodin is dissolved under an appropriate environment, and spray drying is carried out under a high vacuum environment, so that paste forming ratios of the gastrodin can be increased, the overall operation difficulty is lower, and the extraction efficiency is higher.

The invention provides a traditional Chinese medicine composition for treating stroke; the traditional Chinese medicine composition comprises an effective part of rhizoma dioscoreae nipponicae and an effective part of acanthopanax as the active components, wherein the sum of total saponins of rhizoma dioscoreae nipponicae in the effective part of rhizoma dioscoreae nipponicae and general flavones of acanthopanax in the effective part of acanthopanax is 50-90% w/w of the traditional Chinese medicine composition. The invention further provides a preparation method of the traditional Chinese medicine composition, a pharmaceutical preparation containing the traditional Chinese medicine composition, and an application of the traditional Chinese medicine composition or the pharmaceutical preparation in preparation of a medicine for treating qi deficiency and blood stasis in the recovery phase of stroke (cerebral infarction). Pharmacological experimental results show that the traditional Chinese medicine composition has good effects for protecting cerebral ischemia, invigorating the circulation of blood and dispersing blood stasis; furthermore, the material basis is more definite; the chemical components are more clear; the quality is more controllable; the dosage is reduced; and the traditional Chinese medicine composition disclosed by the invention is convenient to take, corresponds with modern requirements, and has a good development prospect.

The invention provides strong loquat syrup and a preparation method thereof, and the preparation method comprises the following steps: (1) adding water into medicinal materials, boiling, filtering, adding water, repeatedly boiling, filtering, and combining filtrates to obtain a water extract; (2) enabling the water extract to pass through macroporous resin, then carrying out gradient elution, and combining eluents to obtain a crude extract; (3) adding water into cane sugar, controlling steam pressure for boiling and cooling, and adding sucrase for enzymolysis to obtain enzymatic hydrolysate; (4) adding the enzymatic hydrolysate into the crude extract, heating, refrigerating, taking supernate, and concentrating to obtain ointment; and (5) adding sodium benzoate into the ointment, boiling, and subsequently blending to obtain a finished product. The strong loquat syrup prepared by the preparation method disclosed by the invention is not only high in syrup yield, but also relatively high in medicinal component content, the stability of the product is relatively good after the strong loquat syrup is placed for a relatively long time, the production process is simple, the equipment requirement is relatively low, the product quality is easy to control, and large-scale industrial production of the strong loquat syrup can be realized.

The invention provides a technology for extracting zanthoxylum pistaciiflorum hayata by utilizing sulfuric acid-ethanol. The technology comprises the following steps: preparing the zanthoxylum pistaciiflorum hayata into coarse grains; adding into 4-6 times of ethanol sulfate solution, soaking for 20-24h and filtering; extracting the drug residue according to the same process and filtering; mixing the two filtrates; neutralizing the filtrates till being neutral by using concentrated NaOH; and reducing pressure and concentrating at 50-60 DEG C, thereby acquiring a zanthoxylum pistaciiflorum hayata extract. A detection test proves that the extract yield of zanthoxylum pistaciiflorum hayata extract and the transfer rate of magnoline are obviously increased according to the technology provided by the invention, the use ratio of the zanthoxylum pistaciiflorum hayata medicinal material is effectively increased, the resource of the zanthoxylum pistaciiflorum hayata medicinal material is saved and the industrialization cost is saved.

The invention provides a hairyvein agrimony detection method and a preparation and quality control method of hairyvein agrimony formula granules, and solves the problem that the content of main components of the hairyvein agrimony formula granules is inconsistent with that of main components of traditional Chinese medicine standard decoction. The quality control method of the hairyvein agrimony formula granules provided by the invention comprises the following steps: acquiring a characteristic chromatogram of the hairyvein agrimony formula granules, and the characteristic chromatogram at least comprises chromatographic peaks corresponding to protocatechuic acid, ellagic acid, isoquercitrin, quercitrin and quercetin. The characteristic spectrum comprises a peak 1 and a peak 5, the characteristic peaks of protocatechuic acid, ellagic acid, isoquercitrin, quercitrin and quercetin are respectively a peak 1 to a peak 5, the characteristic spectrum further comprises a peak 6, the peak of quercetin is taken as a reference peak S2, and the relative retention time of the peak 6 and the reference peak S2 is 1.02 +/-0.1. According to the method, the common control of active ingredients such as flavonoids and phenolic acids is realized, the overall quality control of the hairyvein agrimony formula granules is realized, and the effects of accurately, objectively and effectively controlling the quality of the hairyvein agrimony formula granules and ensuring the effectiveness of clinical medication are achieved.

The invention relates to the technical field of traditional Chinese medicine preparations and particularly relates to a method for improving extract yield of a traditional Chinese medicine extract and application of poria cocos powder. The method for improving the extract yield of the traditional Chinese medicine extract comprises the step of before drying, mixing the poria cocos powder with the traditional Chinese medicine extract. The method for improving the extract yield of the traditional Chinese medicine extract, provided by the invention, only needs to mix the poria cocos powder with the traditional Chinese medicine extract before drying and is simple to operate, the dosage of auxiliary materials can be greatly lowered, and even, the auxiliary materials are not required to be added before drying.