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A method for increasing the content of cordycepin in the fruiting bodies of Cordyceps militaris

A technology of cordycepin and Cordyceps militaris, which is applied in botany equipment and methods, fertilizer mixtures, gardening, etc., can solve the problems that development and utilization have not been paid attention to by people, and the output of Cordyceps militaris is scarce, so as to achieve good application development prospects and improve Effects on quality, increased yield and efficiency

Active Publication Date: 2017-04-05
丹东元尊虫草科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, due to the scarcity of Cordyceps militaris in the wild, its development and utilization have not been valued by people

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] S1. Monascus cultivation:

[0022] S11. Take water-soluble starch 4%, sucrose 5%, peptone 4%, agar 5%, sodium carbonate 0.9% and the remaining amount of water, mix them into a conical flask, sterilize, cool, place them on a slope, and inoculate Monascus species, in an incubator at 30°C, cultured in the dark until the mycelium covered the slope;

[0023] S12. Take maltose 24g / L, peptone 34g / L, mannitol 22g / L, sodium nitrate 4g / L, amino acid chelated zinc 4g / L, potassium dihydrogen phosphate 2g / L and mix, put into a conical flask, and use 60mL Sterile water washes the inclined surface of the conical flask obtained in step S11 to obtain a spore suspension, which is 60% of the seed liquid medium by volume, inoculated, and cultured in liquid state on a rotary shaker at 30° C. at 180 r / min for 1 d;

[0024] S13, take starch 18%, sodium nitrate 0.6%, yeast paste 0.8%, corn steep liquor 1% and mix with the remaining amount of water, adjust the pH value with lactic acid to 4.0,...

Embodiment 2

[0030] S1. Monascus cultivation:

[0031] S11. Mix water-soluble starch 2%, sucrose 3%, peptone 3%, agar 1%, sodium carbonate 0.7% with the remaining amount of water and put them into a conical flask, sterilize, cool, place on a slope, and inoculate Monascus strains , in an incubator at 30°C, cultured in the dark until the hyphae are covered with slopes;

[0032] S12. Mix 20g / L of maltose, 30g / L of peptone, 20g / L of mannitol, 2g / L of sodium nitrate, 2g / L of zinc amino acid chelate, and 1g / L of potassium dihydrogen phosphate. Sterile water washes the inclined surface of the conical flask obtained in step S11 to obtain a spore suspension, which is 50% of the seed liquid medium by volume, inoculated, and cultured in liquid state on a rotary shaker at 30° C. at 180 r / min for 1 d;

[0033] S13, take starch 16%, sodium nitrate 0.4%, yeast paste 0.6%, corn steep liquor 0.8% and mix with the remaining amount of water, adjust the pH value with lactic acid to 4.0, put it into a triangu...

Embodiment 3

[0039] S1. Monascus cultivation:

[0040] S11. Take 3% of water-soluble starch, 4% of sucrose, 3.5% of peptone, 3% of agar, 0.8% of sodium carbonate and the remaining amount of water and put it into a triangular flask, sterilized, cooled, placed on an inclined plane, and inoculated with Monascus species, in an incubator at 30°C, cultured in the dark until the mycelium covered the slope;

[0041] S12. Mix 22g / L of maltose, 32g / L of peptone, 21g / L of mannitol, 3g / L of sodium nitrate, 3g / L of zinc amino acid chelate, and 1.5g / L of potassium dihydrogen phosphate, put them into a conical flask, and use 50mL sterile water was used to wash the inclined surface of the conical flask obtained in step S11 to obtain a spore suspension, which was 55% of the seed liquid medium by volume, inoculated, and cultured in liquid state on a rotary shaker at 30° C. at 180 r / min for 1 d ;

[0042] S13, take starch 17%, sodium nitrate 0.5%, yeast paste 0.7%, corn steep liquor 0.9% and mix with the r...

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PUM

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Abstract

The invention discloses a method for improving the content of cordycepin in cordyceps militaris fruiting bodies. The method comprises the following steps that monascus and cordyceps militaris are independently cultured, then the two microbial strains are mixed for culturing, the mixed microbial strains are exposed to illumination of 200 Ix scattered light no less than 10 hours each day, the temperature is kept at 18-25 DEG C at daytime, the diurnal temperature difference is controlled to be in the range of 5-8 DEG C, illumination is alternated for 14 hours, the relative humidity is controlled to be between 70% and 80%, and ventilation is conducted every day; after the cordyceps militaris send forth stromata, the illumination intensity is enhanced to 800-1000Ix, the temperature is kept at about 22 DEG C, and the air humidity is kept at about 85%; ventilation and air exchange are conducted every day; during the period of the fifteenth day to the twentieth day, the culturing temperature of the cordyceps militaris rises to 29-34 DEG C; then, the culturing temperature of the mixed culture is regulated to a conventional culture temperature for conventional culturing, and the culturing is continued until the harvest time arrives. By the adoption of the method, the yield of the cordyceps militaris fruiting bodies can be obviously improved, the quality of the cordyceps militaris fruiting bodies can further be improved, and the content of the cordycepin in the fruiting bodies is improved by more than 40%.

Description

technical field [0001] The invention relates to the technical field of microorganisms and fermentation thereof, in particular to a method for increasing the content of cordycepin in fruiting bodies of Cordyceps militaris. Background technique [0002] Cordyceps militaris, also known as Cordyceps militaris, belongs to Ascomycota, Sclerotinia, Ergotia, Ergotaceae, Cordyceps genus in fungal taxonomy. Fungi of the genus Cordyceps is a general term for a class of insect-fungi complexes formed on the underground fruiting bodies of insects, spiders or macrocystis plants. Cordyceps militaris is a type species of fungi of the genus Cordyceps. In the wild, it is mainly hosted on the larvae and pupae of some insects of Lepidoptera, Coleoptera and Diptera. Traditional Chinese medicine records that its effects are "sweet in taste, flat in nature, beneficial to the lungs and kidneys. , replenish the essence, stop bleeding and resolve phlegm", which is basically the same as the function o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01G1/04C05G3/00
Inventor 刘晓红
Owner 丹东元尊虫草科技有限公司