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A combination drug for the treatment of acute viral hepatitis

A viral hepatitis and drug technology, applied in the direction of antiviral agents, drug combinations, pharmaceutical formulas, etc., can solve the problems of renal function damage in patients, achieve the effect of less renal function damage, less dosage, and enhanced immunity

Inactive Publication Date: 2018-06-19
程厚华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In actual treatment, antiviral drugs have strong side effects and drug resistance, and will also cause damage to the patient's kidney function

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Weigh the following Chinese medicinal materials by weight: 150 grams of rhubarb, 150 grams of licorice, 150 grams of forsythia, 150 grams of Atractylodes macrocephala, 150 grams of money grass, 150 grams of Scutellaria barbata, 150 grams of turmeric, 150 grams of raspberry, and 150 grams of corn silk .

[0028] Prepare as follows:

[0029] (1) The raw medicinal materials are extracted with 14L of 80% ethanol under reflux, extracted for 2 hours, filtered, the dregs are retained, the ethanol extract is collected, and after the ethanol is recovered under reduced pressure, it is further concentrated to a thick paste, vacuum or microwave dried, and dried extract;

[0030] (2) decocting and extracting the medicinal dregs retained in step (1) with 12 L of water twice, each time for 2 hours, filtering, combining the water extracts, concentrating under reduced pressure to a thick paste, and drying in vacuum to obtain a dry extract;

[0031] (3) Combine the extracts obtained in...

Embodiment 2

[0033] Weigh the following Chinese medicinal materials by weight: 200 grams rhubarb, 200 grams licorice, 200 grams forsythia, 200 grams Atractylodes macrocephala, 200 grams desmodium, 200 grams barbata, 200 grams turmeric, 200 grams raspberry, 200 grams corn silk .

[0034] Prepare as follows:

[0035] (1) The raw medicinal materials are extracted with 18L of 80% ethanol under reflux, extracted for 2 hours, filtered, the dregs are retained, the ethanol extract is collected, and after the ethanol is recovered under reduced pressure, it is further concentrated to a thick paste, vacuum or microwave dried, and dried extract;

[0036] (2) decocting and extracting the medicinal dregs retained in step (1) with 15 L of water twice, each time for 2 hours, filtering, combining the water extracts, concentrating under reduced pressure to a thick paste, and drying in vacuum to obtain a dry extract;

[0037] (3) Combine the extracts obtained in steps (1) and (2), crush them, add 0.2 g of ...

Embodiment 3

[0039] Weigh the following Chinese medicinal materials by weight: 180 grams of rhubarb, 180 grams of licorice, 180 grams of forsythia, 180 grams of Atractylodes macrocephala, 180 grams of money grass, 180 grams of Scutellaria barbata, 180 grams of turmeric, 180 grams of raspberry, 180 grams of corn silk .

[0040] Prepare as follows:

[0041] (1) The raw medicinal materials are extracted with 16L of 80% ethanol under reflux, extracted for 2 hours, filtered, the dregs are retained, the ethanol extract is collected, and after the ethanol is recovered under reduced pressure, it is further concentrated to a thick paste, vacuum or microwave dried, and dried extract;

[0042] (2) decocting and extracting the medicinal residues retained in step (1) with 13 L of water twice, each time for 2 hours, filtering, combining the water extracts, concentrating under reduced pressure to a thick paste, and vacuum drying to obtain a dry extract;

[0043] (3) Combine the extracts obtained in ste...

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PUM

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Abstract

The invention discloses a combined medicine for treating acute viral hepatitis, which comprises the following raw materials in parts by weight: 0.01-0.02 parts of adefovir, 15-20 parts of rhubarb, 15-20 parts of licorice, and 15-20 parts of forsythia 20 parts, 15‑20 parts of Atractylodes macrocephala, 15‑20 parts of Desmodium, 15‑20 parts of Banzhilian, 15‑20 parts of Curcuma, 15‑20 parts of raspberry, 15‑20 parts of corn silk. The preparation method of the combined medicine is as follows: firstly, the raw medicinal material is extracted with 10 times the weight of 80% ethanol under reflux, extracted for 2 hours, filtered, the dregs are retained, the ethanol extract is collected, and the ethanol is recovered under reduced pressure, and then further concentrated to a thick paste , vacuum or microwave drying to obtain a dry extract; then add 8 times the weight of water to the dregs to decoct and extract twice, each time for 1.5 to 2 hours, filter, combine the water extracts, concentrate under reduced pressure to a thick paste, vacuum or Microwave drying to obtain dry extracts; combine the obtained extracts, crush them, add adefovir, and then add starch or dextrin to mix evenly, make tablets, granules or capsules, and pack them separately.

Description

technical field [0001] The invention relates to a combined medicine, in particular to a combined medicine for treating acute viral hepatitis. Background technique [0002] Acute viral hepatitis refers to a wide range of liver inflammatory diseases caused by specific hepatotropic viruses. The incubation period is between 15 and 45 days, with an average of 25 days, and the total course of disease is 2 to 4 months. There are five types of hepatitis A, B, C, D, and E, and A and E are acute hepatitis with a short incubation period. The main symptoms of viral hepatitis are fatigue, loss of appetite, and abnormal liver function. Some patients may have fever and jaundice. Severe hepatitis is dangerous and has a high mortality rate. The main causes of death were hepatic coma, liver failure, electrolyte disturbance and secondary infection. There is no cross-immunity between various types of hepatitis, and they can be infected simultaneously or successively, mixed infection or overl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P1/16A61P31/14A61P31/20A61K31/675
Inventor 程厚华
Owner 程厚华
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