Aerosol precursor containing effective components in anti-inflammatory drug and method for dispersing effective components in anti-inflammatory drug into nanoscale droplets
A technology for medicinal components and anti-inflammatory drugs, applied in the field of aerosol precursors, can solve the problems of high cost of propellants, reduced pressure in the tank, and poor drug atomization effect, so as to improve the effective utilization rate and overcome losses. , the effect of shortening the action time
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Embodiment 1
[0038] An aerosol precursor containing the active ingredients of anti-inflammatory drugs, which includes glycerol, propylene glycol, 1,3-butanediol, flavoring substances and anti-inflammatory drug extracts, and their mass ratio is glycerol: propylene glycol: Anti-inflammatory drug extract = 40:20:1.
[0039] Wherein said anti-inflammatory drug extract is obtained by the method comprising the following steps:
[0040] (1) Impurity removal: dissolving the anti-inflammatory and antipyretic granules in food-grade ethanol, filtering, removing insoluble impurities, and obtaining an ethanol solution of anti-inflammatory and antipyretic granules;
[0041] (2) Decolorization: the ethanol solution of the anti-inflammatory and antipyretic granules obtained in step (1) is passed through a macroporous resin chromatographic column, and is eluted with an ethanol-water solution with a concentration of 50% by volume to remove the pigment components therein; and use molecular distillation The ...
Embodiment 2
[0045] An aerosol precursor containing the active ingredients of anti-inflammatory drugs, which includes glycerol, propylene glycol, 1,3-butanediol, flavoring substances and anti-inflammatory drug extracts, and their mass ratio is glycerol: propylene glycol: Anti-inflammatory drug extract = 40:20:1.
[0046] Wherein said anti-inflammatory drug extract is obtained by the method comprising the following steps:
[0047] (1) Impurity removal: Grinding Xiaoyan Lidan Tablets into powder and dissolving them in food-grade ethanol, filtering to remove insoluble impurities to obtain the ethanol solution of Xiaoyan Lidan Tablets;
[0048] (2) decolouring: the ethanol solution of Xiaoyan Lidan Tablets obtained in step (1) is passed through the first macroporous resin chromatographic column, and is 50 volume % ethanol-water solution eluting with concentration, removes the pigment component wherein; And utilize Solvent is removed by molecular distillation to obtain the first extract; where...
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