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Preparation method and application of a photoelectrochemical sensor based on autio2/bi2s3 modified electrode

A modified electrode and photoelectrochemical technology, which is applied in the direction of material electrochemical variables, can solve the problem of low photoelectric conversion efficiency in the visible light region, and achieve excellent photoelectric conversion characteristics, simple operation, and high-sensitivity detection.

Inactive Publication Date: 2016-07-06
UNIV OF JINAN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to TiO 2 Wide band gap (3.2eV), can only be effectively excited in the ultraviolet region, so the photoelectric conversion efficiency in the visible region is extremely low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1 One is based on AutoO 2 / Bi 2 S 3 Method of the preparation of the optoelectronic chemical sensor of the breast cancer logo of the electrode CA15-3

[0027] (1) Autio 2 / Bi 2 S 3 Preparation of modified electrodes: Cut the ITO conductive glass to 2cm × 0.5cm, and use detergent, acetone, ethanol, and ultrasonic ultrasound for 30 minutes in turn, and blow dry with nitrogen.6 μl, 3mg / mlautio 2 Add the solution to the surface of the electrode, and dry it naturally under room temperature conditions. 6 μL, 3 mg / mlbi 2 S 3 Add the solution to the surface of the electrode and dry it under room temperature.

[0028] (2) CA15-3 of 6 μL, 8 μg / mL capture antibody AB 1 On the surface of the electrode, dry in the refrigerator at 4 ° C, rinse in super pure water;

[0029] (3) The BSA solution with a drop of 3 μL and a mass score of 0.5%on the surface of the electrode, with non -specific activity sites on the surface of the electrode, dry in the refrigerator at 4 ° C;

[0030] (4...

Embodiment 2

[0031] Example 2 One is based on AutoO2 / Bi 2 S 3 Method of the preparation of the optoelectronic chemical sensor of the breast cancer logo of the electrode CA15-3

[0032] (1) Autio 2 / Bi 2 S 3 Preparation of modified electrodes: Cut the ITO conductive glass to 2cm × 0.5cm, and use detergent, acetone, ethanol, and ultrasonic ultrasound for 30 minutes in turn, and blow dry with nitrogen.6 μl, 3mg / mlautio 2 Add the solution to the surface of the electrode, and dry it naturally under room temperature conditions. 6 μL, 4mg / mlbi 2 S 3 Add the solution to the surface of the electrode and dry it under room temperature.

[0033] (2) CA15-3 of 10 μg / ml of drops of 6 μL, 10 μg / ml capture antibody AB 1 On the surface of the electrode, dry in the refrigerator at 4 ° C, rinse in super pure water;

[0034] (3) BSA solution with a drop of 3 μL and a mass score of 1.0%on the surface of the electrode, with non -specific activity sites on the surface of the electrode, dry in the refrigerator at 4 ...

Embodiment 3

[0036] Example 3 One is based on AutoO 2 / Bi 2 S 3 Method of the preparation of the optoelectronic chemical sensor of the breast cancer logo of the electrode CA15-3

[0037] (1) Autio 2 / Bi 2 S 3 Preparation of modified electrodes: Cut the ITO conductive glass to 2cm × 0.5cm, and use detergent, acetone, ethanol, and ultrasonic ultrasound for 30 minutes in turn, and blow dry with nitrogen.6 μl, 3mg / mlautio 2 Add the solution to the surface of the electrode, and dry it naturally under room temperature conditions. 6 μL, 5 mg / mlbi 2 S 3 Add the solution to the surface of the electrode and dry it under room temperature.

[0038] (2) CA15-3 of 6 μL, 12 μg / ml of drops of drops of 6 μL, 12 μg / ml capture antibody AB 1 On the surface of the electrode, dry in the refrigerator at 4 ° C, rinse in super pure water;

[0039] (3) The BSA solution with a drop of 3 μL and a mass score of 2.0%is on the surface of the electrode, and the non -specific activity site on the surface of the electrode is d...

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Abstract

The invention relates to a preparation method and application of a photoelectrochemical sensor for a breast cancer marker CA15-3 based on an AuTiO2 / Bi2S3 modified electrode, and belongs to the technical fields of new functional materials and biosensing detection. Specifically, the invention combines AuTiO2 core-shell nanomaterials with photoelectric catalysis activity and Bi2S3 nanorods on electrodes to prepare a label-free photoelectrochemical sensor to realize rapid and ultrasensitive detection of breast cancer marker CA15-3. This method is of great significance to the early diagnosis and prognosis of breast cancer.

Description

Technical field [0001] The present invention involves an AutoO -based 2 / Bi 2 S 3 The preparation method and application of the optoelectronic chemical sensor of the breast cancer logo CA15-3 of the electrode.Specifically, AUTIO with photoelectric catalytic activity will be on the electrode 2 Materials and BI 2 S 3 Nano-rods are compound, preparing a label-free photoelectric chemical sensor to achieve fast and super-sensitive testing of breast cancer logo CA15-3.It belongs to the field of new functional materials and biosensor detection technology. Background technique [0002] Calling chemical testing is an emerging detection method in biological analysis.During the chemical testing process, light is the inspiration signal, and the electrical signal is used as a detection signal.Due to the complete separation of the stimulation signal and detection signal, the background signal is reduced, and the mechanism of chemistry to call chemistry has higher sensitivity than traditional e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/26
Inventor 柳懿芯魏琴马洪敏王晓东吴丹胡丽华范大伟颜兆庆王超刘振
Owner UNIV OF JINAN