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New application of theacrine in promotion of fat burning

A technology of fat burning and tecanin, applied in the fields of application, food science, digestive system, etc., can solve the problems of weakening the effect of drugs and the inability to effectively use free fatty acids

Inactive Publication Date: 2015-10-14
何蓉蓉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, so far, people have not screened ideal lipid-lowering and weight-loss drugs in promoting neutral lipolysis. The reason is that the free fatty acids generated by lipolysis cannot be effectively utilized and will be recycled again to synthesize triglycerides. A futile cycle that weakens the drug's effect

Method used

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  • New application of theacrine in promotion of fat burning
  • New application of theacrine in promotion of fat burning
  • New application of theacrine in promotion of fat burning

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The preparation of Teacrine dripping pills: take 5.0g of the real compound Teacrine (Theacrine), mix well with 60009.5g of polyethylene glycol, melt at 80°C, cool in simethicone, drop into pills, Obtain 100 drop pills.

Embodiment 2

[0030] Preparation of Teacrine soft capsules: take 5.0 g of the real compound Theacrine (Theacrine), mix well with 45.0 g of vegetable oil, and send it into a soft capsule packaging machine to obtain 100 soft capsules.

Embodiment 3

[0032] Preparation of Teacrine Tablets: Take 5.0 g of the real compound Theacrine, add starch solution, granulate, compress into tablets, and subpackage to obtain 100 tablets.

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Abstract

The invention discloses an application of a compound, theacrine, of which the structure is represented as the formula (I), in preparation of a product for promotion of fat burning, blood fat reducing, body fat reducing and fat accumulation reducing. The application of the theacrine is based on that the theacrine can effectively activate activity of SirT3 protease in mitochondria, enhance the functions of key proteins in [beta]-oxidization and oxidative phosphorylation, activate the activity of downstream AMPK inhibiting acetyl coenzyme A carboxylase (ACC), improve metabolism of fatty acid in mitochondria and reduce synthesis of fatty acid, so that the theacrine promotes the fat burning and then achieves the effects of weight losing and fat reducing.

Description

technical field [0001] The present invention relates to a new application of the compound Theacrine, in particular to the application of Theacrine in the preparation of medicines, diets or health products for promoting mitochondrial energy metabolism to reduce fat and lose weight. Background technique [0002] Hyperlipidemia and obesity are common metabolic disorders in modern society, which seriously endanger people's health and bring many social and psychological problems. According to WHO statistics, the global obesity population has increased significantly since 1980. In 2008, there were nearly 500 million obese patients in the global population, and this population was significantly associated with hypertension, insulin resistance, and hyperlipidemia. disease. Because obesity has become one of the factors affecting human health in modern society, it has attracted widespread attention. In the development process of lipid-lowering and weight-loss drugs, people have succ...

Claims

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Application Information

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IPC IPC(8): A61K31/522A61P3/06A61P3/04A61P1/16A23L1/30A23L2/52
Inventor 何蓉蓉李怡芳王国恩栗原博
Owner 何蓉蓉
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