The New Application of the Extract from the Whole Plant of Cauliflower

A technology of plant extracts and ashweed, applied in plant raw materials, medical preparations containing active ingredients, plant/algae/fungus/moss components, etc., can solve the problem of anti-lung cancer activity and its mechanism of action that have not been explored, Cancer efficacy and other issues

Active Publication Date: 2018-10-02
KUNMING UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there are relatively few studies on the anticancer efficacy of this plant. Scholars such as Menka Khoobchandani found that the gray vegetable was extracted with petroleum ether, ethanol and methanol, and found that the methanol phase extract had the most obvious inhibition on the growth of breast cancer cells, but Its anti-lung cancer activity and its mechanism of action have not been explored

Method used

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  • The New Application of the Extract from the Whole Plant of Cauliflower
  • The New Application of the Extract from the Whole Plant of Cauliflower
  • The New Application of the Extract from the Whole Plant of Cauliflower

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The preparation of the whole plant petroleum ether phase extract of the whole plant of the ashweed, specifically comprises the following steps:

[0020] (1) Dry the collected branches and leaves of the whole plant of Pleurotus chinensis in the shade to obtain 184.25g of dried whole plant of Pleurotus chinensis, mix with 95% ethanol and soak overnight, and then ultrasonically extract 3 times, the temperature of ultrasonic extraction is 50°C , the power is 200W, each extraction is 0.5 h, and then the ultrasonic extraction solution is filtered to obtain filtrate 1, and then the filter residue is soaked in 95% ethanol with the same concentration as the initial ratio, and the same extraction process as above is repeated continuously to obtain filtrate 2-n, until Concentration 95% ethanol extract until colorless, finally combine all filtrates to obtain a total concentration 95% ethanol extract.

[0021] (2) Use a rotary evaporator to carry out vacuum distillation on the total...

Embodiment 2

[0024] (1) Dry the collected branches and leaves of the whole plant of Glycyrrhiza mellifera in the shade to obtain 184.25 g of dried whole plant of Glycyrrhizae lentils, mix with 95% ethanol and soak overnight, and then ultrasonically extract 4 times, the temperature of ultrasonic extraction is 60°C , with a power of 200W, extract for 1 hour each time, then filter the ultrasonic extraction solution to obtain filtrate 1, then soak the filter residue with 95% ethanol at the same concentration as the initial ratio, and repeat the same extraction process above to obtain filtrate 2-n, until Concentration 95% ethanol extract until colorless, finally combine all filtrates to obtain a total concentration 95% ethanol extract.

[0025] (2) Use a rotary evaporator to carry out vacuum distillation on the total concentration of 95% ethanol extract of the ash dish to obtain the extract with a concentration of 95% ethanol, and then dissolve it with distilled water.

[0026] (3) Use petroleu...

Embodiment 3

[0028] (1) Dry the collected branches and leaves of the whole plant of Glycyrrhiza chinensis in the shade to obtain 184.25g of dried whole plant of Glycyrrhiza syringae, mix with 95% ethanol and soak overnight, and then ultrasonically extract 5 times, the temperature of ultrasonic extraction is 80°C , with a power of 200W, extracting for 2 hours each time, then filtering the ultrasonic extraction solution to obtain filtrate 1, then soaking the filter residue with 95% ethanol at the same concentration as the initial ratio, and repeating the same extraction process above to obtain filtrate 2-n, until Concentration 95% ethanol extract until colorless, finally combine all filtrates to obtain a total concentration 95% ethanol extract.

[0029] (2) Use a rotary evaporator to carry out vacuum distillation on the total concentration of 95% ethanol extract of the ash dish to obtain the extract with a concentration of 95% ethanol, and then dissolve it with distilled water.

[0030] (3) ...

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Abstract

The invention discloses new application of a whole chenopodium album linn plant extract, and belongs to the technical field of medicines and natural medicines. The new application is the application of the whole chenopodium album linn plant petroleum ether phase extract to preparing an anti-non-small cell lung cancer medicine. The preparation method of the extract comprises the following steps: 95% ethyl alcohol is used as an extracting agent, the ultrasonic extraction method is utilized for extracting a whole Chenopodium album Linn plant so as to obtain an ethyl alcohol total extract, then, petroleum ether is used for extracting the ethyl alcohol total extract, and an extract liquor is concentrated to obtain a petroleum ether phase extract. The whole chenopodium album linn plant petroleum ether phase extract has the obvious effects on suppressing cell multiplication and apoptosis induction.

Description

technical field [0001] The invention relates to a new application of a plant extract of the whole plant of the ashweed, and belongs to the technical field of medicine and natural medicine. Background technique [0002] Cancer is a major disease that seriously threatens human health and has become a major public health problem facing the world today. Lung cancer is the leading cause of cancer death in the world. Lung cancer can be divided into small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) according to pathological morphology. Among them, non-small cell lung cancer (NSCLC) Lung cancer accounts for about 85% of all lung cancers. Most non-small cell lung cancers are diagnosed at advanced stage and the 5-year survival rate is only 15%-16%. In addition, most chemotherapeutic drugs currently used in clinical practice have limited curative effect, have relatively large toxic and side effects, and are easily tolerated by tumors, seriously affecting the therap...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P35/00
Inventor 赵扬赵婷李拓梁超潘卉冯阳
Owner KUNMING UNIV OF SCI & TECH
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