Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Diuresis inducing plaster for relieving ascites due to cirrhosis

A technology of liver cirrhosis ascites and water plaster, which is applied in the field of medicine, can solve the problems of poor medication compliance of patients, prominent side effects of diuretics, and repeated occurrence of ascites, so as to solve the problems of poor metabolism and detoxification ability, simple and easy medication method, and improve the The effect of bioavailability

Active Publication Date: 2015-11-25
THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
View PDF0 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine treatment (oral diuretics, albumin supplementation, ascites reinfusion, TIPS) can reduce ascites to a certain extent, but the long-term effect is not good, and ascites tends to recur
Western medicine has the following problems in the treatment of cirrhotic ascites: ① liver cirrhosis complications such as gastrointestinal hemorrhage, hepatic encephalopathy, electrolyte disturbance, spontaneous peritonitis, functional renal failure, etc., once they occur, they will promote the occurrence and development of ascites. Easy-to-treat turns into difficult-to-treat, poor curative effect of western medicine
③ The side effects of long-term use of diuretics are prominent: long-term use can cause male breast swelling and pain; high doses of oliguria can cause hyperkalemia
⑤ Drugs that promote diuresis by reducing portal hypertension, some have been denied, and some have been proven to be effective, but their application value has been offset by their damage to the liver
Western medicines have high toxic and side effects, and gastrointestinal side effects and liver and kidney function damage cannot be avoided. Sometimes the treatment is counterproductive, and some patients lose confidence in conventional treatment. However, oral Chinese medicines cause patients to adhere to medication due to gastrointestinal side effects and long-term medication. Poor performance, but can not achieve the desired effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0021] Below in conjunction with embodiment the present invention is described in further detail.

[0022] A diuretic plaster for relieving ascites due to liver cirrhosis. Raw materials by weight are 20g Gansui, 40g Petunias, 40g Radix Astragali, 40g Atractylodes Rhizoma, 20g Cassia and 60g Qingpi. Mix 90g of crushed traditional Chinese medicine with 20ml of honey and 4ml of laurocaprazine solution to make a paste, stir evenly, and spread it on the patch. The diameter of the patch is 20cm, and the thickness of the medicine is 0.5cm. Moisture, Shuidao, and Zhongwan points, once a day, 4 hours each time.

[0023] The present invention is applied clinically and receives good effect, and total effective rate is 93.3%; Specific clinical data are as follows:

[0024] one. Diagnostic criteria

[0025] Refer to the diagnostic criteria for liver cirrhosis in the "Viral Hepatitis Prevention and Treatment Program" jointly revised by the Infectious Diseases and Parasitic Diseases Bran...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a diuresis inducing plaster for relieving ascites due to cirrhosis. The plaster is prepared by the following steps: selecting and drying the following raw materials by weight: euphorbia kansui, semen pharbitidis, astragalus membranaceus, bighead atractylodes rhizome, cortex cinnamomi and pericarpium citri reticulatae viride, grinding the raw materials and filtering by virtue of a sieve of 200 meshes; blending the ground materials with honey and a transdermal penetration enhancer to obtain a paste, and uniformly stirring; spreading 80-100 of the paste on patch according to the ascites area of a patient; and sticking and applying to Shenque acupuncture point, Guanyuan acupuncture point, Shuifen acupuncture point, Shuidao acupuncture point and Zhongwan acupuncture point, wherein the diuresis inducing plaster is mainly used for treating intractable ascites caused by decompensated liver cirrhosis. The diuresis inducing plaster has functions of warming kidney and invigorating spleen, regulating qi circulation and inducing diuresis; the diuresis inducing plaster is capable of overcoming the shortcoming of an oral medicine which is always poor in effect on cirrhosis patients who have poor metabolism and detoxification capacities, and the plaster has the advantages of being low in toxic and side effects and capable of attacking pathogen without causing hurt to healthy qi; the plaster can make up the deficiency of internal therapy by Western medicine and traditional Chinese medicine; the plaster is convenient and easy in administration, easily acceptable to patients, significant in diuresis effect and durable in curative effect; and upon clinical observation, total effective rate of treatment is 93.3%.

Description

Technical field [0001] The present invention involves the field of medicine, especially a water plaster used to remove the hepatitis and hardcore ascites, which can treat stubborn ascites caused by cirrhosis. Background technique [0002] Hepatitis cirrhosis is a common chronic derived liver disease that is common in clinical clinical, which is formed by one or more etiology for a long time or repeated effects.Ledtimulation is an important symbol of transforming liver cirrhosis from a compensation period to a periodic period. It has a very complicated formation mechanism. Patients with active hepatitis and liver cirrhosis often often use ascites and use diuretics for a long time.Poor, ascites are difficult to subscribe.Hepatotemated ascites belong to the category of "accumulation" and "swelling" in traditional Chinese medicine.Due to the long time of the patient's lesions, the lack of righteousness, the internal stagnation of the evil, often the cold and heat mixed, and the defic...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/752A61K9/70A61P1/16A61P7/10A61K35/644
Inventor 费景兰顾亚姣郭敏刘姝刘杨春陈茜刘婷婷
Owner THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products