Medicinal preparation for treating children's viral myocarditis

A technology for viral myocarditis and drugs, applied in the direction of antiviral agents, drug combinations, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2015-11-25
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the lack of targeted western medicine specific therapy and individual differences in individual reactivity, especially in children, adverse drug reactions will cause serious consequences. Currently, immunosuppressants, interferon and cardiomyocyte nutrition are mostly used clinically. Symptomatic treatment such as medicine and traditional Chinese medicine treatment, but the effect of long-term use is not good

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: the preparation of the pharmaceutical preparation for the treatment of children's viral myocarditis

[0035] Recipe: Astragalus 35 grams, Ophiopogon japonicus 24 grams, Salvia miltiorrhiza 17 grams, Pueraria 13 grams, Predict seed 13 grams, Semen jujube 20 grams, Saffron 20 grams, Magnolia officinalis 10 grams, Guangzao 8 grams, Lotus seeds 8 grams , Perindopril 4 grams, Losartan 8 grams.

[0036] Preparation:

[0037] (1) Weigh astragalus, Radix Ophiopogon japonicus, Salvia miltiorrhiza, Pueraria lobata, Foreknowledge seed, jujube seed, saffron, magnolia officinalis, jujube, lotus seeds according to the formula, add water to decoct twice, filter (adding for the first time) 8 times the amount of water, decocted for 2 hours; add 6 times the amount of water for the second time, decocted for 1.5 hours), combined the filtrate, concentrated to an extract with a relative density of 1.2 (50°C), dried under reduced pressure at 80°C, and pulverized, Pass through ...

Embodiment 2

[0039] Embodiment 2: the preparation of the pharmaceutical preparation for the treatment of children's viral myocarditis

[0040] Recipe: Astragalus 30 grams, Ophiopogon japonicus 30 grams, Salvia miltiorrhiza 15 grams, Pueraria 15 grams, Predict seed 10 grams, Jujube kernel 25 grams, Saffron 12 grams, Magnolia officinalis 12 grams, Jujube 5 grams, Lotus seeds 10 grams , Perindopril 3 grams, Losartan 10 grams.

[0041] The preparation method is the same as in Example 1.

Embodiment 3

[0042] Embodiment 3: the preparation of the pharmaceutical preparation for the treatment of children's viral myocarditis

[0043] Recipe: 40 grams of Astragalus, 20 grams of Ophiopogon japonicus, 20 grams of Salvia miltiorrhiza, 10 grams of kudzu root, 15 grams of Zhizhizi, 15 grams of jujube kernels, 25 grams of saffron, 8 grams of magnolia officinalis, 10 grams of jujube, 5 grams of lotus seeds , Perindopril 5 grams, Losartan 6 grams.

[0044] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention discloses a medicinal preparation for treating children's viral myocarditis. The medicinal preparation is prepared from the following raw materials in parts by weight: 30-40 parts of radix astragali, 20-30 parts of radix ophiopogonis, 15-20 parts of salvia miltiorrhiza, 10-15 parts of radix puerariae thomsonii, 10-15 parts of fructus akebiae, 15-25 parts of spina date seed, 12-25 parts of stigma croci, 8-12 parts of flos magnoliae officinalis, 5-10 parts of fructus choerospondiatis, 5-10 parts of lotus seed, 3-5 parts of perindopril and 6-10 parts of losartan. The invention further discloses a method for preparing the medicinal preparation. According to the medicinal preparation disclosed by the invention, components of traditional Chinese medicine and components of western medicine are combined, and the goal of treating both principal and secondary aspects of the disease is achieved; the treatment effect is good, and no toxic or side effect is generated.

Description

technical field [0001] The invention relates to a pharmaceutical preparation for treating children's viral myocarditis. Background technique [0002] Viral myocarditis is a common and frequently-occurring disease of the cardiovascular system. It is a confinement or diffuse inflammation of the myocardium caused by viral infection. Most of them are children and adults under the age of 40. According to the World Health Organization (WHO) Global Virus Surveillance Research Report, 20% of sudden death cases in newborns and children are caused by viral myocarditis; The morbidity rate among infants and children is 360 / 100,000, and the mortality rate is 8%. After viral infection invades the myocardium, it will cause focal or diffuse myocardial interstitial exudation and myocardial fibrosis and necrosis. Severe diffuse myocarditis may lead to severe arrhythmia, heart failure, cardiogenic shock, and even sudden death; it may also persist, leading to cardiac hypertrophy and gradually...

Claims

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Application Information

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IPC IPC(8): A61K38/05A61P9/00A61P31/12A61K31/4178
Inventor 孟晓慧张萍
Owner SHANDONG UNIV
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