The invention belongs to the field of preparation of radioactive nuclide, and discloses a preparation method for a radioactive 68Ge solution. The preparation method comprises the following steps of: preparing a solid Ga4Ni alloy target containing gallium and nickel by using an electro-deposition method; performing CYCLONE 30 irradiation on the alloy target to prepare an alloy target containing radioactive 68Ge; cooling; electrolyzing the target; separating and purifying electrolyte on a silica gel column; desorbing 68Ge by using a nitric acid solution; evaporating a desorption solution to dryness; and dissolving solid-state 68Ge to prepare the radioactive 68Ge solution for a 68Ge-68Ga generator. The method has the advantages of simple equipment for preparing the Ga4Ni alloy target, quickness in method, high repeatability, stable process, firm target, high quality and easiness in target shooting. The 68Ge has the advantages of stable purification process, completeness in separation from impurity ions, nuclear purity of more than 99.995 percent, chemical purity of more than 98 percent, desorption efficiency of more than 98 percent, easiness in operation, no pollution and contribution to conventional and large-scale production.