38results about How to "Treatment applicable" patented technology

The present invention relates to alpha-type zinc- phthalocyanine nanowires (ZnPc NWs) having enhanced water solubility and water dispersibility, to a composite of an alpha-type zinc-phthalocyanine nanowire / phenothiazine, to a method for preparing same, and to a photosensitizer including same or a pharmaceutical composition including same for preventing or treating cancers. Since the alpha-type zinc-phthalocyanine nanowires or the composite of alpha-type zinc-phthalocyanine nanowire / phenothiazine according to the present invention exhibit dual traits, i.e., photothermal and photodynamic traits in single molecules, they are very useful for the development of a multifunctional molecular system and can also be usefully applied to light therapy of cancers due to their good light therapeutic effects. Also, the composite of alpha-type zinc-phthalocyanine nanowire / phenothiazine itself can exhibit fluorescence to facilitate the introduction of an imaging system, so that diagnosis and treatment can be simultaneously performed using a single substance.

The invention discloses traditional Chinese medicine paste for treating hemorrhoids. The traditional Chinese medicine paste comprises a traditional Chinese medicine composition, vegetable oil and a matrix. The traditional Chinese medicine composition comprises, by weight, 0.6 to 2.0 portions of phellodendron, 0.6 to 2.0 portions of coptis root, 0.6 to 2.0 portions of radix scutellariae, 0.6 to 2.0 portions of rhubarb, 0.6 to 2.0 portions of honeysuckle, 0.6 to 2.0 portions of radix sanguisorbae, 0.6 to 2.0 portions of Chinese gall and 0.3 to 1.0 portion of borneol. Vegetable oil is rapeseed oil, soybean oil or sesame oil. The matrix comprises one or more of albolene, beeswax, stearic acid, lanolin, hydrogenated vegetable oil, dimethicone, glycerol, gelatin, polyethylene glycol 4000 and polyethylene glycol 6000. The traditional Chinese medicine paste is prepared from common traditional Chinese medicines, has a cheap price, high infection resistance, a fast rate of eliminating swelling and alleviating pain, good curative effects and no toxic or side effect and is suitable for treatment on external hemorrhoid, internal hemorrhoid and mixed hemorrhoid and cure after a hemorrhoid operation.

The invention discloses a fully humanized single-chain antibody of targeted BCMA as well as a preparation method and application thereof. The single-chain antibody is formed by connecting a heavy chain variable region and a light chain variable region through a flexible connecting peptide, and the sequences of skeleton regions and CDR regions of the light chain and the heavy chain are derived from human, so that compared with murine and humanized antibodies, the single-chain antibody has higher specificity and lower immunogenicity; the specificity on BCMA is good; and a theoretical basis can be provided for treating diseases related to BCMA expression, and the method is particularly suitable for diagnosis and treatment of tumors such as multiple myeloma.

The invention relates to the fields of traditional Chinese medicine science and medicines, and especially relates to a medicine for treating spondylodynia and hyperosteogeny, and a preparation method thereof. The medicine is an external preparation prepared from rhizoma drynariae, Achyranthes bidentata, panax notoginseng, Aconitum kusnezoffii and ginger, and preferably is a vinum, a paste, an ointment and a film agent. Clinical test confirms that the medicine has a very good therapeutic effect on hyperosteogeny, cervical spondylosis and various types of spondylodynia, and has the advantages of wide application range, safety in use, and very low treatment cost.

The invention relates to a device and a method for treating tumors through irreversible electroporation, belonging to the technical field of tumor treatment. The device mainly comprises a square wave pulse generation and measurement system, a signal conversion system, a man-machine communication system, a measurement control system and a power supply system. In the method, the device and a therapeutic electrode are used for treating the tumors through a program. Under the circumstance of no injection of chemotherapeutic drugs, microsecond square wave pulses are applied to tumor tissues, the entire tumor cell is fully damaged, so that the tumor cell dies due to irreversible electroporation, and the harm on the body of a patient caused by the side effect of the chemotherapeutic drugs is radically avoided. The invention has the characteristics of short treatment time, no pain, good treatment effect, high safety, convenient use, simple operation, convenient popularization and application and the like. The device and the method can be widely used for treating the tumors of human and animals, and are especially applicable to human tumor treatment.

The invention relates to a Chinese traditional medicine for treating cardiopathy, which comprises Chinese medicinal herbs including Chinese angelica root, Ligusticum wallichii, root of red rooted saliva, prepared rhizome of rehmannia, radix paeoniae rubrathe, red ginseng, white atractylodes rhizome, astragalus root, honey-fried licorice root, raw astragalus root, cimicifuga rhizome, schisandra fruit, Bupleurum root, medicated leaven, malt, rhizoma dioscoreae, motherwort, Cinnamomum cassia, cassia twig, asaryl, dodder seed, lilyturf root, prepared aconite root, dried ginger, aniseed, broomrape, safflower, epimeddium, grassleaved sweetflag rhizome, zanthoxylum piperitum, deer horn gum, notoginseng, and leeches.

The present invention relates to certain 2-(2,4,5-substituted anilino)pyrimidine compounds represented by the following formula I and applications thereof. These compounds or salts thereof show higher inhibition of EGFR in activated or drug-resistant mutant forms than in wild-type EGFR. Due to the reduced toxicity associated with wild-type EGFR inhibition, the compound or its salt is expected to have excellent pharmacodynamic properties, higher metabolic stability, better permeability of the blood-brain barrier, and is more suitable for use as a therapeutic agent, Especially suitable for the treatment of cancer. Therefore, these compounds or their salts can be used to prepare drugs for treating certain mutation forms of EGFR-mediated diseases, especially non-small cell lung cancer.

The invention relates to a Chinese medicinal composition for treating cancer and a preparation method thereof and belongs to the technical field of medicines. The Chinese medicinal composition for treating the cancer is mainly prepared from ten traditional Chinese medicines, namely radix sophorae flavescentis, aspongopus, capillary artemisia, curcuma zedoary, bamboo juice, uniflower swisscentaury root, rhizoma smilacis glabrae, corydalis tuber, lily and costustoot. The Chinese medicinal composition for treating the cancer has obvious inhibiting effect on growth of tumour, can be used for treatment of various cancers, is applicable to treatment on liver cancer patients and is especially applicable to advanced liver cancer patients.

The invention relates to the technical field of medicinal preparations, and concretely discloses a cisplatin-liposome preparation, and a preparation method and an application thereof. An improved formula and the improved method in the above technical scheme make the cisplatin liposome improve the bioavailability of cisplatin medicines and prolong the detention time of the medicines in bodies, and also make cisplatin be enriched in cancerous organs, thereby the dosage is reduced, curative effects are enhanced, the toxic and side effects of the medicines are reduced, and the medicines are suitable for treating various tumor diseases.

The invention relates to stomatological medicines, and particularly relates to a compound traditional Chinese medicine composition for treating parotitis. The compound traditional Chinese medicine composition for treating parotitis is prepared from the following components in parts by weight: 5-10 parts of saffron crocus, 5-10 parts of myrrh, 15-20 parts of lilac daphne flower bud roots, 15-20 parts of plantain herb, 10-15 parts of flowers carthami, 10-15 parts of fructus forsythiae, 10-15 parts of cactus, 15-20 parts of phaseolus calcaratus, 10-15 parts of the root barks of the peony trees, 3-5 parts of apiaries, 1-3 parts of scorpio and 5-10 parts of borneol. The invention further relates to a preparation method of the compound traditional Chinese medicine composition for treating parotitis as an external coating ointment. The compound traditional Chinese medicine provided by the invention has the advantages of good effect, quick effect, simple treatment method, no side effect and the like, is convenient to use, is suitable for treating parotitis caused by various causes, and is particularly suitable for treating mumps.

The invention discloses a Schlemm canal expansion stent which is in a one-way spiral shape. The outer diameter of the expansion stent is matched with the inner diameter of a Schlemm canal. The length of the expansion stent is matched with the length of the Schlemm canal. Or, the length of the expansion stent is matched with the length of the nidus of the Schlemm canal. The expansion stent can also be a secondary expansion stent. Or, the expansion stent is formed by connecting a plurality of secondary expansion stents in series. The Schlemm canal expansion stent is simple in structure, low in manufacturing process requirement, low in manufacturing cost, and beneficial for popularization and application. The Schlemm canal expansion stent is not only suitable for treatment of a late glaucoma patient, but also suitable for treatment of an early glaucoma patient and treatment of a secondary glaucoma patient.

The invention belongs to the technical field of medicine and relates to a Cu(DDC) 2 Nano-core liposome and its preparation method and application, specifically related to Cu(DDC) 2 Nano core liposome, its preparation method and its application in the preparation of medicine for treating liver cancer. The Cu(DDC) 2 Nanonuclear liposomes contain Cu(DDC) as an inner layer 2 Nanoparticles and the outer layer of phospholipids. The Cu(DDC) 2 Nanoparticles contain: CuCl 2 , sodium diethyldithiocarbamate (DDTC), and phospholipids, the weight ratio of each component is: (12‑51): (17‑68): (10‑20). The phospholipid layer comprises cholesterol, DSPE‑PEG 2000 , Phospholipids, Phospholipids, Cholesterol, DSPE‑PEG 2000 The mass ratio of is: (10‑20): (5‑10): (18‑42). The present invention prepares Cu(DDC) coated with phospholipids in the inner layer by reverse phase microemulsion polymerization 2 Nanoparticles, further by membrane hydration, encapsulate the outer layer of phospholipids. Cu(DDC) of the present invention 2 Nano-nuclear liposomes can significantly prolong the circulation time of drugs in the body and increase Cu(DDC) 2 antitumor effect.

The invention provides a short peptide for antibacterial, antipruritic, anti-inflammatory, detumescence, and scar removal and application thereof. The amino acid main sequence of the short peptide fragments, analogs, derivatives, and variants of the short peptide has ≥70% identity and ≥90% similarity with the short peptide amino acid main sequence; short peptides, nucleotides, short Peptide fragments, short peptide analogs, short peptide derivatives and short peptide variants are used for the preparation of antibacterial, antipruritic, anti-inflammatory and detumescent drugs for various skin disinfection or treatment of skin diseases, for the preparation of neurodermatitis, contact dermatitis, chronic eczema , Drug application for topical treatment of insect bite dermatitis and pruritic skin diseases. The short peptide involved in the invention has a clear molecular structure, mature production technology, and the finished product is non-toxic, harmless, and has no side effects. Its remarkable feature is that it does not leave scars after being cured.

The invention relates to a traditional Chinese medicine composition for treating chronic glomerulonephritis and a preparation method thereof. The traditional Chinese medicinal composition is prepared from the following raw materials: rehmannia glutinosa, yam, wolfberry, dogwood meat, dodder, tortoise board glue, antlers Gum, Polyporus, Poria, Bupleurum, Atractylodes, Guizhi, Cicada slough, windproof, Rhizoma Imperatae, Achyranthes. The traditional Chinese medicine composition for treating chronic glomerulonephritis has a reasonable composition, can achieve the effect of tonifying both yin and yang of the kidney, and the effect of tonifying the kidney is stable and lasting. While fundamentally treating the loss of nephrons in chronic glomerulonephritis, it can also effectively relieve symptoms such as proteinuria, hematuria, and hypertension.

The invention discloses an olmesartan medoxomil / rosuvastatin compound preparation and a preparation method thereof. The olmesartan medoxomil / rosuvastatin compound preparation is characterized by being prepared from a main drug and auxiliary materials, wherein the main drug is prepared from olmesartan medoxomil and rosuvastatin; the auxiliary materials comprise filler, a disintegrating agent, an adhesive, lubricant and a flow aid; the olmesartan medoxomil / rosuvastatin compound preparation is prepared through the process steps of raw material selecting, preparation, mixing, soft material preparing, pelleting, drying, particle finishing, total blending, finished product forming and the like. Olmesartan medoxomil is an ARB antihypertensive drug, has approximately-ideal pharmacological characteristics, and has an excellent antihypertensive effect. Rosuvastatin is a blood lipid regulating drug and is suitable for primary hypercholesterolemia (IIa type, including heterozygous familial hypercholesterolemia) or hybrid dyslipidemia (IIb type) with dyslipidemia incapable of being properly controlled through diet control and other non-drug treatment (such as sports therapy and weight losing). The compound preparation is formed by olmesartan medoxomil and rosuvastatin and is more suitable for treating patients with cardiovascular diseases, and the compliance of the patients is improved.

The invention relates to a Chinese medicinal composition for treating lung cancer. The composition consists of an active ingredient or the active ingredient and a pharmaceutically acceptable carrier. The active ingredient is prepared from the following pharmaceutical ingredients: adenophora, asparagus root, dwarf lilyturf tuber, shizandra berry, American ginseng, unibract fritillary bulb, loquat leaves, barbed skullcap herb, astragalus, scorch-fried three immortals, powdered notoginseng root, arisaema cum bile, pinellia tuber, bamboo shavings, patrinia heterophylla Bge., bittersweet herb, common hongfennel root, Chinese paris rhizome and redroot gromwell root. The Chinese medicinal composition of the invention has the effect of clearing heat and resolving toxin, and eliminating blood stasis and detoxicating, is used for surgery and treatment after radiation treatment for lung cancer caused by accumulated toxin and blood-stasis obstruction, has no toxic or side effects, has an obvious treatment effect and a total effective rate of more than 95.0 percent, and is an ideal medicament for treating lung cancer.