Application of α-lactose in the preparation of medicine for preventing and treating acute pancreatitis

A technology for acute pancreatitis and lactose, applied in the field of medicine, can solve problems such as the pathogenesis is not completely clear
CN105124349BActive Publication Date: 2020-01-03JIANGNAN UNIV
5 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JIANGNAN UNIV
Publication Date
2020-01-03

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses the application of alpha-lactose for preparing health care foods capable of preventing and treating acute pancreatitis, and belongs to the field of health care foods. The alpha-lactose can reduce pancreatic tissue oedema, serum amylase, and the level of pancreatic tissue medulla peroxidase MPO so as to reduce an inflammatory reaction in an acute pancreatitis process; besides, the alpha-lactose can reduce inflammation mediators in pancreatic tissues and pancreatic acinar cells, such as an MCP-1 level and a TNF- alpha level. In addition, the alpha -lactose has the effect of restraining the activation of signal routes for regulating protein kinase (ERK1 / 2MAPK) and nuclear factors KB (NF-KB) protein outside cells, reduces the soaking of immunocyte, such as neutrophilic granulocyte and macrophage, in pancreatic tissues, has a notable protective effect on acute pancreatitis, and can be used for preparing health care foods capable of preventing and treating acute pancreatitis.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the application of alpha-lactose in the preparation of medicines for preventing and treating acute pancreatitis, which belongs to the field of medicine. Background technique

[0002] Lactose is a disaccharide formed by the combination of one molecule of glucose and one molecule of fructose through glycosidic bonds. It mainly exists in mammalian milk and is one of the necessary components to maintain the nutritional health of infants and young children. Studies have shown that lactose can induce the expression of antimicrobial peptide LL-37 in epithelial cells, revealing the immunomodulatory function of lactose. In addition, a diet low in fermentable oligosaccharides, disaccharides, and polyols can effectively reduce functional gastrointestinal symptoms in patients with irritable bowel syndrome, which shows that lactose can also regulate inflammation while providing nutrition.

[0003] Acute pancreatitis is one of the common di...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More