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Auxiliary lipid-lowering drug and preparation method thereof

A technology for assisting blood lipid lowering and drugs, applied in the directions of drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve problems such as affecting liver and kidney functions, reduce arteriosclerosis index, reduce atherosclerosis index, and increase high-density lipoprotein. horizontal effect

Inactive Publication Date: 2015-12-09
长春康彼达科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the demand for drugs for hyperlipidemia is also increasing. At present, the commonly used lipid-lowering drugs on the market mainly include chemical drugs and Chinese patent drugs, which have remarkable therapeutic effects, but long-term consumption will affect liver and kidney functions.

Method used

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  • Auxiliary lipid-lowering drug and preparation method thereof
  • Auxiliary lipid-lowering drug and preparation method thereof
  • Auxiliary lipid-lowering drug and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Take 3 parts by weight of the ethanol extract of the leaves of Snake japonica, 3 parts by weight of the water extract of Moringa oleifera leaves, 4 parts by weight of perilla oil, 10 parts by weight of evening primrose oil, 6 parts by weight of soybean lecithin, and 1 part by weight of beeswax. Mix evening primrose oil and beeswax, heat and stir at 60 degrees Celsius to dissolve, add perilla oil and stir evenly after dissolving, put it at 40-50 degrees Celsius, add ethanol extract of grape leaves and water extract of Moringa oleifera leaves, and grind for 30 minutes Finally, add soybean lecithin, mix and grind evenly, stir evenly for 60 minutes at 50 degrees Celsius, and pack into soft capsules. When taken twice a day, three capsules (0.4-0.6g) each time. Other dosage forms can be taken with reference to this dosage.

[0033]Wherein the preparation method of the ethanol extract from the leaves of Snake-toothed Grape is: crush the leaves of Snake-toothed Grape into powd...

Embodiment 2

[0036] Take 4 parts by weight of the ethanol extract from the leaves of Snakelodon grape, 4 parts by weight of the leaf extract of Moringa oleifera, 2 parts by weight of perilla oil, 8 parts by weight of evening primrose oil, 3 parts by weight of soybean lecithin, and 5 parts by weight of beeswax. Mix the obtained evening primrose oil and beeswax, heat and stir at 60 degrees Celsius to dissolve, add perilla oil and stir evenly after dissolving, put it at 40-50 degrees Celsius, add ethanol extract of grape leaves and water extract of Moringa oleifera leaves, grind After 30 minutes, add corresponding proportion of soybean lecithin, mix and grind evenly, stir evenly for 60 minutes under the condition of 50 degrees Celsius, and pack into soft capsules.

[0037] Wherein the preparation method of the ethanol extract from the leaves of Snake-toothed Grape is: crush the leaves of Snake-toothed Grape into powder or granules with a size of 20 mesh to 80 mesh, and use 8-10 times the amoun...

Embodiment 3

[0040] Take 5 parts by weight of the extract of grape leaves of Snake dentata, 5 parts by weight of leaf extract of Moringa oleifera, 3 parts by weight of perilla oil, 5 parts by weight of evening primrose oil, 4 parts by weight of soybean lecithin, and 8 parts by weight of beeswax. Mix the obtained evening primrose oil and beeswax, heat and stir at 60 degrees Celsius to dissolve, add perilla oil and stir evenly after dissolving, put it at 40-50 degrees Celsius, add ethanol extract of grape leaves and water extract of Moringa oleifera leaves, grind After 30 minutes, add corresponding proportion of soybean lecithin, mix and grind evenly, stir evenly for 60 minutes under the condition of 50 degrees Celsius, and pack into soft capsules.

[0041] Wherein the preparation method of the ethanol extract from the leaves of Snake-toothed Grape is: crush the leaves of Snake-toothed Grape into powder or granules with a size of 20 mesh to 80 mesh, and use 8-10 times the amount of 60-80% eth...

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Abstract

Disclosed are an auxiliary lipid-lowering drug and a preparation method thereof. The drug comprises, by weight, 3-5 parts of ampelopsis grossedentata ethanol extract, 3-5 parts of moringa oleifera leaf water extract, 2-4 parts of perilla oil, 5-10 parts of evening primrose oil, 3-6 parts of soybean phospholipid and 1-8 parts of beeswax. The method includes: subjecting ampelopsis grossedentata powder to ethanol reflux extract, drying the extract, and grinding the dried extract to fine powder; adding moringa oleifera leaves into water for decoction extraction, concentrating, drying and grinding the extract, mixing the evening primrose oil with the beeswax, heating with stirring for dissolving, adding the perilla oil prior to stirring evenly, adding the ampelopsis grossedentata ethanol extract and the moringa oleifera leaf water extract, stirring prior to adding the soybean phospholipid for mixing and uniform grinding, and encapsulating the obtained powder. Pharmacodynamics experiments show that the drug has unexpected results in lowering lipid.

Description

technical field [0001] The invention relates to the field of health food, in particular to an auxiliary blood lipid-lowering drug and a preparation method thereof. Background technique [0002] At present, cardiovascular disease has become one of the main causes of death in adults in my country, and abnormal blood lipids, especially hypercholesterolemia, is one of the main risk factors leading to the development of cardiovascular disease. With the improvement of modern people's quality of life, fast pace of life, high work pressure, and less physical exercise, the incidence of hyperlipidemia is increasing year by year in my country, which includes hypercholesterolemia, hypertriglyceridemia and complex hyperlipidemia. Lipidemia, which is one of the main factors leading to atherosclerosis and coronary heart disease. It also has a non-negligible impact on kidneys, peripheral circulation, immune system, and blood system diseases. Therefore, the demand for drugs for hyperlipidem...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61P3/06A61K35/644
Inventor 赵宝琴姜文月崔莹胡萍高畅周丽梅王美慧
Owner 长春康彼达科技有限公司
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