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Agent or method for treatment and/or prevention of accelerated energy expenditure and/or diminished energy expenditure functionality

A technology of energy consumption and preventive agents, applied in skin care preparations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of shortening animal life, reducing the quality of life of mammals, increasing risks, etc., to achieve the basis of prevention Low metabolism, prevention of lowering of basal body temperature, high safety effect

Inactive Publication Date: 2015-12-23
MATSUTANI CHEM INDS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a result, the risk of various chronic diseases such as type II diabetes, hyperlipidemia, arteriosclerosis, and hypertension is increased, and the quality of life of mammals is reduced, and the life span of animals is shortened.

Method used

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  • Agent or method for treatment and/or prevention of accelerated energy expenditure and/or diminished energy expenditure functionality
  • Agent or method for treatment and/or prevention of accelerated energy expenditure and/or diminished energy expenditure functionality
  • Agent or method for treatment and/or prevention of accelerated energy expenditure and/or diminished energy expenditure functionality

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0118] "Metabolism test in rats by long-term administration of D-psicose"

[0119] [experimental method]

[0120] Using 3-week-old male Wistar rats (purchased from Japan SLC, Inc.), the influence of long-term administration of D-psicose on energy metabolism was investigated. After pre-feeding with a commercially available powder feed (trade name MF: Oriental Yeast Co., Ltd.) for one week, the body weight was measured, and they were divided into 2 groups with equal body weight (8 animals in each group). One group was a sucrose intake group, and the other was a sucrose+psicose intake group.

[0121] After the rats were divided into two groups, they freely ingested the experimental feed and water shown in Table 2, under the feeding conditions (temperature 22 ± 1 ° C, humidity 58 ± 2%, lighting period 8:00 ~ 20:00, dark period 20 :00 to 8:00 the next day). The measurement of energy metabolism was carried out as follows on the 5th to 7th weeks after ingesting the test feed. Fir...

Embodiment 2

[0128] "Metabolism test by single intake of D-psicose in rats"

[0129] 〔experimental method〕

[0130] The effects of a single intake of D-psicose on energy expenditure, carbohydrate burning, and lipid burning in humans were investigated. Each energy metabolism value was calculated by the indirect calorimetry method calculated by measuring the subject's respiration (oxygen consumption and carbon dioxide excretion). In this test, 6 healthy people without smoking habits (average age 34.8 years old, 3 males, 3 females, average BMI 21.4kg / m 2 ), implemented by the single-blind crossover method of 2 groups. In addition, after the content of the experiment was fully explained to the subjects based on the guidelines stipulated in the Declaration of Helsinki, a consent form for the experiment was obtained from all the subjects.

[0131] After fasting the subjects 12 hours before the start of the test, they ingested 5 g of D-psicose or added 10 mg of high-intensity sweetener asparta...

Embodiment 3

[0137] "Somatosensory test by continuous intake of D-psicose in humans"

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Abstract

To provide a solution employing a food product that is effective in countering the detrimental effects of diminished energy metabolism in humans or other mammals requiring treatment and / or prevention of accelerated energy expenditure and / or diminished energy expenditure functionality. A method involving successive intake of a functional food product of rare sugar containing at least D-glucose, to effectively improve energy expenditure.

Description

technical field [0001] The present invention relates to the use of D-psicose for improving energy metabolism. In more detail, the present invention relates to the use of D-psicose and / or derivatives thereof for the promotion of energy expenditure and / or the treatment and / or prevention of decreased energy expenditure function. Background technique [0002] Energy metabolism refers to the energy in, out, conversion, and utilization of biological activities involving the decomposition and absorption of nutrients and the production of adenosine triphosphate (ATP). In mammals including humans, especially in mammals of advanced age, mammals in menopause, or mammals with health or other problems that cause a decrease in energy metabolism, energy metabolism is often reduced or deteriorated. Such mammals have reduced thermogenic function and low basal metabolism, and therefore tend to consume less energy than intake energy. The ingested nutrients cannot be fully used in heat produc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7004A23K1/16A23L1/30A61K8/60A61K31/7008A61K31/7012A61P3/02
CPCA61K8/60A61K31/7004A61K31/7008A61K31/7012A61Q19/00A61K2800/10A61K2800/92A23K20/163A23L29/30A23L33/10A23L7/00A23L5/00A23L21/00A23L9/00A23L33/125A61K31/121A61P3/02A61P3/04A61P3/06A61P43/00A61P3/10A23V2002/00
Inventor 山田贵子吉川裕子松尾达博木村友纪林范子
Owner MATSUTANI CHEM INDS CO LTD
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