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A traditional Chinese medicine composition for preventing and treating rupture and bleeding of esophageal varices due to liver cirrhosis

A technology of varicose veins and composition, which is applied in the field of traditional Chinese medicine composition for prevention and treatment of rupture and bleeding of esophageal varices due to liver cirrhosis, can solve the problems of inability to prevent the increase of vascular resistance, inability to tolerate surgery, unsuitable for surgery, etc., achieve convenience in taking, improve Esophageal varices, simple effects

Active Publication Date: 2019-01-11
ZHAOQING MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most patients with liver cirrhosis and portal hypertension are not suitable for surgery or cannot tolerate surgery; sclerotherapy and varicose vein ligation have more adverse reactions; drug prevention is mostly carried out from the perspective of hemodynamics, including non-selective β receptor blockers, nitrate vasodilators and calcium channel blockers, etc. These drugs can slow down the occurrence of esophageal variceal bleeding to a certain extent, but have no obvious effect on liver cirrhosis itself that causes portal hypertension, and cannot Prevent the progression of hepatic fibrosis and the increase in intrahepatic and portosystemic vascular resistance caused by cirrhosis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] [Example 1] Prescription

[0026] Turtle shell 30g, Curcuma 30g, Sanleng 30g, American ginseng 30g, Astragalus 20g, Paeoniae Alba 30g, Atractylodes macrocephala 20g, Poria cocos 20g, rhubarb 10g, musk 1g, licorice 15g.

Embodiment 2

[0027] [embodiment 2] preparation method and usage, dosage

[0028] Step 1. Weighing: It consists of the effective components of the following raw materials by mass: Turtle Shell 30g, Curcuma 30g, Sanleng 30g, American Ginseng 30g, Astragalus 20g, Radix Paeoniae Alba 30g, Atractylodes Rhizoma 20g, Poria 20g, Rhubarb 10g, Musk 1g, Licorice 15g.

[0029] Step 2. Purification: Classify and remove impurities from the weighed traditional Chinese medicines, wash them, and dry them in the sun or dry them.

[0030] Step 3, processing: Turtle shell, Curcuma, Sanleng, and white peony are all vinegar-baked, Atractylodes bran is fried, and the rest of the medicines are used as conventional decoction pieces.

[0031] Tortoise shell vinegar broiling method: stir-fry the clean sand with strong fire (the suitable temperature is to put the paper into the pot for about 1 minute to turn brownish yellow), add the clean turtle shell, stir constantly, fry until crisp and loose, and the surface is ...

Embodiment 3

[0042] [Example 3] clinical example

[0043](1) Li, male, 36 years old, lives in Xinyi Village, Ma'an Town. After suffering from hepatitis B, he suffered from liver pain and abdominal distension repeatedly for 7 years, aggravated with oliguria and black stool for 10 days, and went to see a doctor on October 12, 1995. The admission symptoms were dark complexion, thin constitution, many spider moles on the head, face, neck and chest, abdominal distension, varicose veins on the abdominal wall, positive mobile dullness, splenomegaly and hard texture, percussion pain in the liver area, and edema of both lower extremities. Abnormal liver function. B-ultrasound examination revealed that the inner diameter of the portal vein was 16mm and the inner diameter of the splenic vein was 12mm. Fiber gastroscopy showed 3 varicose veins 25cm away from the incisors, with a width of about 7mm. There were red signs on the surface of the varicose veins near the cardia, and the gastric mucosa was ...

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PUM

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Abstract

The invention discloses traditional Chinese medicine composition for preventing and treating cirrhosis esophageal variceal bleeding. The composition is prepared from traditional Chinese medicinal materials in parts by mass as follows: 30 parts of turtle carapaces, 30 parts of zedoray rhizomes, 30 parts of common burreed rhizomes, 30 parts of American ginseng, 20 parts of milkvetch roots, 30 parts of white peony roots, 20 parts of largehead atractylodes rhizomes, 20 parts of poria cocos, 10 parts of rhubarb, 1 part of musk and 15 parts of liquorice roots. The traditional Chinese medicine composition has functions of benefiting qi, promoting blood circulation, removing stasis and eliminating concretions, has significant curative effects on symptoms such as hepatalgia, jaundice, ascites, spider nevi, liver palms, tongue margin ecchymoses, splenomegaly and the like which are shown by cirrhosis esophageal varices, and has the effective rate higher than 95%, and a patient suffering from the cirrhosis esophageal variceal bleeding cannot bleed again after keeping taking the traditional Chinese medicine composition for treatment.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine products, and in particular relates to a traditional Chinese medicine composition for preventing and treating rupture and bleeding of esophageal varices due to liver cirrhosis. Background technique [0002] Hemorrhage of esophageal varices due to liver cirrhosis is one of the most common and serious complications in the decompensated stage of liver cirrhosis, with a mortality rate as high as 40% to 70%. Therefore, preventing the deterioration of liver cirrhosis and preventing bleeding from esophageal varices is very important to prolong the life of patients. At present, there are many clinical methods commonly used to prevent esophageal variceal bleeding due to liver cirrhosis, mainly including surgery, sclerotherapy, variceal ligation, and drugs to reduce portal pressure. However, most patients with liver cirrhosis and portal hypertension are not suitable for surgery or cannot tolerat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/14A61P1/16A61P7/04A61K35/586A61K35/55
Inventor 李力强张贵锋邹锦慧
Owner ZHAOQING MEDICAL COLLEGE
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