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Preparation method and animal nutrition application of animal anti-anemia micro-capsules

An anti-anemia and animal technology, which is applied in the direction of microcapsules, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems affecting the economic benefits of animal breeding, lack of iron and cobalt trace elements, animal poisoning environment, etc., and achieve element types reduction, production process simplification, and obvious anti-anemia effect

Active Publication Date: 2016-02-17
SICHUAN AGRI UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, most animals are kept in captivity, and unreasonable dietary formulas are prone to cause animal anemia due to lack of iron and cobalt trace elements, which seriously affects the economic benefits of animal breeding
Trace element feed additives are likely to cause uneven mixing and cause animal poisoning and environmental pollution

Method used

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  • Preparation method and animal nutrition application of animal anti-anemia micro-capsules
  • Preparation method and animal nutrition application of animal anti-anemia micro-capsules
  • Preparation method and animal nutrition application of animal anti-anemia micro-capsules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A. Method

[0027] 1. Adopt the low-iron feed formula recommended by the Association of Official Analytical Chemists (AOAC) to formulate animal feed: 54% corn starch, 40% milk powder, 5% soybean oil, and 1% salt. Choose mice with a body weight of (40±5) g, half male and half male, fed with low-iron diet, and collect blood every week to detect changes in blood cells. When the blood physiological indicators are lower than the reference value, it means that the anemia model is constructed successfully (Table 1). The anemia model mice were divided into control group and experimental group. The test group was fed with iron-cobalt composite microcapsules at a dose of 0.1 g / kg, orally once every other day.

[0028] 2. Compare the blood physiological index and body weight changes before and after microcapsules infusion 45 days.

[0029] B. Results

[0030] 1. After the mice were fed the low-iron feed for a period of time, the blood physiological indicators were detected as ...

Embodiment 2

[0043] A. Method

[0044] 1. Adopt the low-iron feed formula recommended by the Association of Official Analytical Chemists (AOAC) to formulate animal feed: 54% corn starch, 40% milk powder, 5% soybean oil, and 1% salt. Choose mice with a body weight of (40±5) g, half male and half male, fed with low-iron diet, and collect blood every week to detect changes in blood cells. When the blood physiological indicators are lower than the reference value, it means that the anemia model is constructed successfully (Table 1). The anemia model mice were divided into control group and experimental group. The test group was fed with iron-cobalt composite microcapsules at a dose of 0.2 g / kg, orally administered once every other day.

[0045] 2. Compare the blood physiological index and body weight changes before and after microcapsules infusion 45 days.

[0046] B. Results

[0047] 1. After the mice were fed the low-iron feed for a period of time, the blood physiological indicators were...

Embodiment 3

[0060] A. Method

[0061] Twenty anemic mice were divided into a test group and a control group, 10 in each group. The test group was fed with iron-cobalt composite microcapsules 0.15g / kg body weight, and the control group was fed with normal saline 0.15ml / kg body weight, every other day, for a total of 4 times. The anemia mice were observed 15 days after administration.

[0062] B. Results

[0063]

[0064] C. Summary

[0065] Anemia mice fed with iron-cobalt composite microcapsules have increased appetite, better mental state than the control group, and bright coat, indicating that this preparation can enhance the immunity of mice, promote metabolism, and improve the health level of animals.

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Abstract

The invention discloses a preparation method and animal nutrition application of animal anti-anemia micro-capsules. The anti-anemia micro-capsules which take ferric citrate as the main ingredient, take cobalt chloride as capsule cores and take acrylic resin as capsule materials are prepared from tiny capsules which are prepared through the step that ferric citrate powder and cobalt chloride are taken as the main active ingredients to be fully heated, stirred and dissolved in oil-water solvent. The animal anti-anemia micro-capsules overcome the defect that animal poisoning and environmental polluting are prone to be caused due to uneven material stirring and mixing of a conventional feed additive, are balanced in feeding, safe, effective, convenient to use, free of toxic and side effects and capable of simultaneously and slowly releasing and supplementing iron-cobalt trace elements and have the effects of promoting growth and resisting anemia and the important significance on development of the breeding industry.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and relates to a preparation method of microcapsules for promoting clinical anti-anemia in animals, in particular to a preparation method of anti-anemia drug microcapsules for animals. Background technique [0002] Trace elements are an important material basis for the survival and healthy growth of animal organisms. Among them, the main functions of cobalt and iron in the body are: cobalt plays a physiological role in the form of vitamin B12 and coenzyme B12, and the main function of vitamin B12 is to stimulate hematopoietic function. Iron and protein make up hemoglobin, which is the main component of red blood cells. Iron is also involved in catalyzing the production of antibodies, increasing the activity of various bactericidal enzymes and phagocytes, and improving immunity. [0003] At present, most animals are kept in captivity, and unreasonable dietary formulas are prone to ca...

Claims

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Application Information

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IPC IPC(8): A61K33/24A61K9/50A61P7/06A61P37/04A61K31/295
CPCA61K9/5026A61K33/24A61K33/26A61K2300/00
Inventor 胡延春汤承岳华乔艳许锐光吴冬梅蔡海王远微
Owner SICHUAN AGRI UNIV
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