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Traditional Chinese medicine composition for treating primary hypertension and preparation method thereof

A technology of essential hypertension and composition, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of insignificant effect and slow onset of effect, so as to reduce adverse reactions and achieve effective The effect of fast and simple preparation process

Inactive Publication Date: 2016-03-02
叶宗耀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Antihypertensive drugs need long-term or life-long application, drug safety and patient tolerance are very important, traditional Chinese medicine treatment of high blood pressure drugs have few side effects and stable drug effect, can be used safely for a long time, and have broad prospects, but existing prevention and treatment of high blood pressure The existing traditional Chinese medicine has insignificant effect, slow onset and other deficiencies. It is of great significance for the clinical treatment of essential hypertension to seek a Chinese medicine composition with remarkable effect, fast onset and convenient taking.

Method used

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  • Traditional Chinese medicine composition for treating primary hypertension and preparation method thereof
  • Traditional Chinese medicine composition for treating primary hypertension and preparation method thereof
  • Traditional Chinese medicine composition for treating primary hypertension and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The traditional Chinese medicine composition of Example 1 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0031] 25 parts of apocynum, 20 parts of stinky phoenix tree, 16 parts of Vitex, 15 parts of Prunella vulgaris, 12 parts of capillary, 15 parts of Uncaria, 13 parts of Chuanxiong, 10 parts of angelica, 5 parts of dendrobium, 8 parts of wolfberry, 6 parts of Atractylodes macrocephala, Hawthorn 10 parts and licorice 8 parts.

[0032] The preparation method is as follows:

[0033] S1: Weigh all the Chinese medicinal materials according to the traditional Chinese medicine prescription, wash away the impurities, grind them separately after drying, pass through a 80-mesh sieve, and set aside;

[0034] S2: Take the Vitex vitae coarse powder, place it in a supercritical carbon dioxide extraction device, add 45% of the weight of the coarse powder with a volume fraction of 75% ethanol, control the carbon dioxide flow rate to 1...

Embodiment 2

[0039] The Chinese medicine composition of Example 2 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0040] 30 parts of apocynum, 28 parts of phoenix tree, 23 parts of Vitex, 20 parts of Prunella vulgaris, 20 parts of capillary, 25 parts of Uncaria, 20 parts of Chuanxiong, 17 parts of angelica, 15 parts of dendrobium, 17 parts of wolfberry, 10 parts of Atractylodes macrocephala, 17 parts of hawthorn and 15 parts of licorice.

[0041] The preparation method is the same as in Example 1.

Embodiment 3

[0043] The Chinese medicine composition of Example 3 of the present invention is mainly prepared from the following raw materials in parts by weight:

[0044] 28 parts of apocynum, 25 parts of sycamore, 20 parts of Vitex, 18 parts of Prunella vulgaris, 16 parts of capillary, 18 parts of Uncaria, 16 parts of Chuanxiong, 15 parts of angelica, 12 parts of dendrobium, 15 parts of wolfberry, 8 parts of Atractylodes macrocephala, Hawthorn 15 parts and licorice 9 parts.

[0045] The preparation method is as follows:

[0046] S1: Weigh all the Chinese medicinal materials according to the traditional Chinese medicine prescription, wash away the impurities, grind them separately after drying, pass through a 80-mesh sieve, and set aside;

[0047] S2: Take Vitex vitae coarse powder, put it in a supercritical carbon dioxide extraction device, add 35% of the weight of the coarse powder with a volume fraction of 75% ethanol, control the carbon dioxide flow rate to 20L / h, the extraction pres...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating primary hypertension and a preparation method thereof. The traditional Chinese medicine composition is prepared from, by weight, 25-30 parts of apocynum venetum, 20-28 parts of harlequin glorybower leaves and twigs, 16-23 parts of vitex, 15-20 parts of selfheal, 12-20 parts of herba artemisiae scopariae, 15-25 parts of uncaria, 13-20 parts of ligusticum wallichii, 10-17 parts of radix angelica sinensis, 5-15 parts of dendrobe, 8-17 parts of lycium barbarum, 6-10 parts of bighead atractylodes rhizomes, 10-17 parts of fructus crataegi and 8-15 parts of liquorice. The traditional Chinese medicine composition is reasonable in formula and high in synergistic effect, is significant in curative effect, stable in medicine effect and little in medicine side effect when the traditional Chinese medicine composition is used for treating the primary hypertension and has the significant clinical popularization value.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating essential hypertension and a preparation method thereof. Background technique [0002] According to the WHO standard, the normal blood pressure of the human body is systolic blood pressure 140mmHg and (or) diastolic blood pressure 90mmHg, beyond this range can be diagnosed as hypertension. Hypertension is a common cardiovascular disease, which is defined as a persistent increase in systemic arterial pressure. Hypertension secondary to kidney, endocrine and nervous system diseases is called secondary hypertension, accounting for 5% to 10% of hypertensive patients; and hypertension whose cause has not been clarified so far is called primary hypertension. hypertension. Essential hypertension accounts for more than 90% of hypertensive patients, and is often accompanied by disorders of fat and glucose me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P9/12
Inventor 叶宗耀邹锦新
Owner 叶宗耀
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