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Chronic nonbacterial prostatitis treating pharmaceutical composition

A non-bacterial, prostatitis technology, applied in the field of medicine, can solve the problems of high toxicity and side effects, unsatisfactory treatment effect, etc., and achieve the effect of less adverse reactions

Inactive Publication Date: 2016-03-30
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, α-receptor blockers and non-steroidal anti-inflammatory drugs are often used clinically to treat this disease. Although the above drugs can alleviate the symptoms of patients to a certain extent, they have relatively large toxic and side effects after long-term use. The treatment effect is not ideal

Method used

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  • Chronic nonbacterial prostatitis treating pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The preparation of embodiment 1 Chinese medicine extract

[0013] Weigh 2.5kg Shiwei, 1.4kg Dipsacus, 1.0kg Salt Dipsacus, 1.0kg fried Sophora japonica, 2.5kg Coix Seed, 0.9kg Cornus officinalis, 0.4kg Cinnamon, 0.7kg Vitex and 0.7kg Xingguan fruit, combine and crush , add water and decoct 3 times, add 120L of water for the first time, boil for 2 hours, then add 100L of water for the second time, boil for 1.5 hours, add 90L for the third time, boil for 1.5 hours , combine the decoction, concentrate under reduced pressure at 0.08MPa and 65°C to a relative density of 1.15, add 95% (v / v) ethanol to make the alcohol content reach about 75% (v / v), stir, and let stand After 24 hours, take the supernatant, recover ethanol under reduced pressure at 0.08MPa, concentrate to a thick paste, freeze-dry, and crush through a 100-mesh sieve to obtain dry powder of the Chinese medicine extract.

Embodiment 2

[0014] The preparation of embodiment 2 capsules

[0015] (1) Take by weighing the Chinese medicine extract dry powder 80g that prepares by embodiment 1 prescription process, and cross the recipe quantity lactose 200g of 100 mesh sieves, microcrystalline cellulose 100g and sodium carboxymethyl starch 30g, mix homogeneously;

[0016] (2) use ethanol solution with a volume concentration of 55% as a binding agent, make a soft material from the mixed raw and auxiliary materials in step (1), granulate with a 40 mesh screen, dry at 25°C to obtain dry granules, 40 mesh sieve whole grain;

[0017] (3) After mixing the dry granules prepared in step (2) with 3.5 g of magnesium stearate, fill the capsule shells, and each capsule contains 80 mg of Chinese medicine extract.

Embodiment 3

[0018] Example 3: Study on the curative effect of traditional Chinese medicine on patients with chronic nonbacterial prostatitis

[0019] 70 patients with chronic non-bacterial prostatitis, whose clinical manifestations and various examination results were in line with the clinical diagnostic criteria of chronic non-bacterial prostatitis, their age ranged from 62 to 79 years old, with an average age of (68.1±4.7) years old, Their course of disease was 3 to 10 years, with an average course of (5.9±1.7) years. We used the random number table method to divide the 70 patients into the control group (35 cases) and the observation group (35 cases). There were no significant differences in general information such as age, course of disease, and condition between the two groups, and they were comparable.

[0020] The patients in the control group were treated with conventional western medicine. The specific method was: let the patients take finasteride tablets (National Pharmaceutical...

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Abstract

The present invention discloses a chronic nonbacterial prostatitis treating pharmaceutical composition, which comprises a traditional Chinese medicine extract and a pharmaceutical adjuvant, wherein the traditional Chinese medicine extract is prepared by carrying out water extraction and alcohol precipitation on the following raw materials by weight: 19-30 parts of pyrrosia lingua, 10-17 parts of dioscorea septemloba thunb, 8-13 parts of dipsacus asper stir-fried with salt-water, 8-13 parts of fried sophora flower, 19-30 parts of coix seed, 6-12 parts of cornus officinalis, 3-5 parts of cinnamomum cassia presl, 5-9 parts of fructus viticis, and 5-9 parts of xanthoceras sorbifolium bunge. According to the present invention, the total effective rate of the chronic nonbacterial prostatitis treating effect of the pharmaceutical composition is high, and the adverse reactions are less.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating chronic nonbacterial prostatitis. Background technique [0002] Chronic nonbacterial prostatitis is a very common male reproductive system disease in clinical practice, which mostly occurs in middle-aged and elderly men, and accounts for a large proportion of outpatients in urology department. In recent years, the incidence of the disease has been increasing year by year. The pathogenesis of chronic nonbacterial prostatitis is relatively complicated, and most people think that the occurrence of the disease is closely related to genetic factors and environmental factors. At present, α-receptor blockers and non-steroidal anti-inflammatory drugs are often used clinically to treat this disease. Although the above-mentioned drugs can alleviate the symptoms of patients to a certain extent, they have relatively large toxic and side...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P13/08
CPCA61K36/11A61K9/4858A61K36/185A61K36/40A61K36/489A61K36/54A61K36/77A61K36/85A61K36/8945A61K36/8994A61K2236/331A61K2236/53A61K2300/00
Inventor 邱志磊刘华强徐立柱王荃
Owner QINGDAO MUNICIPAL HOSPITAL
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