Preparation method of chewable tablets containing chitosan oligosaccharide

Abstract

The invention discloses a preparation method of chewable tablets containing chitosan oligosaccharide. In terms of the total weight of the chewable tablets containing the chitosan oligosaccharide, the ratio of the chitosan oligosaccharide to collagen to gelatin is (1%-5%):(20%-40%):(60%-80%). The method comprises steps as follows: (1) the chitosan oligosaccharide, the collagen and the gelatin are mixed in solid states; (2) a chitosan oligosaccharide, collagen and gelatin mixture obtained in Step (1) is added to purified water with the weight 20-40 times that of the mixture, and a mixture is stirred at the temperature of 61-85 DEG C for 10-20 min and introduced to a filter net for press filtering treatment twice; (3) chitosan oligosaccharide, collagen and gelatin homogenate obtained in Step (2) is poured into a die, and the thickness of a homogenate layer is controlled to range from 5 mm to 30 mm; (4) the die containing the chitosan oligosaccharide, collagen and gelatin homogenate in Step (3) is placed into a freezing dryer to be prefreezed at the temperature of subzero 40 DEG C for 40-60 min and then subjected to vacuum pumping for freeze-drying until the moisture content of a freeze-dried film is controlled to range from 3wt% to 8wt%; (5) the chewable tablets are prepared from the chitosan oligosaccharide, collagen and gelatin film prepared in Step (4) with a die cutting method.

Description

technical field [0001] The invention belongs to the field of food science, in particular, the invention relates to a preparation method of a chitosan oligosaccharide-containing chewable tablet. technical background [0002] Chitosan is a binary compound linked by most of 2-amino-2-deoxy-D-glucopyranose and a small amount of 2-acetylamino-2-deoxy-D-glucopyranose through β-(1-4) glycosidic bonds. Linear polymers are usually a pure natural polysaccharide organic polymer obtained by deacetylation of chitin extracted from the shells of shrimps, crabs, insects, or cell walls of fungi and algae. A highly alkaline polysaccharide. [0003] Oligochitosan, also known as chitosan oligosaccharide, is an oligomeric oligosaccharide formed after the main chain of chitosan is broken by physical, chemical or enzymatic degradation. It is the only basic amino oligosaccharide with positive charge in nature. The unique molecular structure of polyoligosaccharides makes it have a variety of biolo...

AI Technical Summary

Problems solved by technology

Traditional products containing oligochitosan are mainly used for its functions of enhancing immunity, anti-tumor, regulating blood lipid and regulating blood pressure; Less, chitosan oligosaccharide oral cleaning tablet (application number 201010500093.6) discloses a kind of chitosan oral cleaning tablet and preparation method thereof, consists of chitosan, xylitol, sorbitol, stearic acid, abrasives, Prepared with sweeteners and essences, but the taste of the product is not ideal and the application is not very convenient

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