Drop array chip and preparation method thereof

An array chip and droplet technology, applied in the field of biochemical analysis, can solve the problems of high cost, unstable flow rate, complex processing technology, etc., and achieve the effects of accurate and efficient morphology, excellent performance and simple operation.
CN105505742AInactive Publication Date: 2016-04-20SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
Publication Date
2016-04-20
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention discloses a drop array chip which comprises a substrate. The substrate is provided with hydrophilic areas and hydrophobic areas, and the hydrophilic areas and the hydrophobic areas are alternately arranged to form a hydrophilic-hydrophobic array. The invention further discloses a preparation method of the drop array chip. According to the drop array chip, a large number of array type drop structures with uniform and controllable morphologies can be precisely and efficiently generated through the hydrophilic-hydrophobic property of the surface of the drop array chip, a foundation is provided for complex biochemical application based on drops, and meanwhile the advantages of being low in cost and capable of being reused are achieved.
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Description

technical field

[0001] The invention belongs to the field of biochemical analysis, in particular to a droplet array chip and a preparation method thereof. Background technique

[0002] In recent years, micro-total analysis systems based on droplet arrays have been widely used in the fields of life analysis chemistry research due to their advantages of miniaturization, integration, automation, throughput, speed, sensitivity, and portability. Many typical experimental operations, Such as mixing, stirring, sampling, metering, etc. can all be carried out in the droplet array, and multi-component simultaneous detection can be realized. At present, a variety of droplet array chips have been put into practical use, such as for the preparation of sample DNA, PCR reaction, electrophoresis detection, electrospray ion mass spectrometry detection, etc.

[0003] However, at present, most commonly used droplet structure generation methods are microfluidic chip droplet technology, such as...

Claims

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