The invention discloses a microfluid self-driven paper base micro-fluidic
chip and a preparation method and application thereof .The preparation method comprises the steps that
titanium dioxide particles are subjected to
silanization treatment to obtain super-hydrophobic
coating liquid,
filter paper is soaked in the
coating liquid, natural
drying is performed at
room temperature, and due to the fact that super-hydrophobic nano particles are adsorbed to
filter paper filter, a super-hydrophobic
filter paper piece of a micro-nano
composite structure is obtained; the geometric dimension of the micro-fluidic
chip is designed on a
mask plate, regional selective
exposure is carried out on the micro-fluidic
chip through deep
ultraviolet light (UV) under the assistance of the
mask plate, and therefore the designed pattern of the micro-fluidic chip is copied to the filter paper; the micro-fluidic chip comprises the filter paper and a hydrophilic-hydrophobic layer
coating the
surface layer of the filter layer; the hydrophilic-hydrophobic layer is provided with at least one hydrophilic flow channel, gradient-changing hydrophilic patterns are designed in the hydrophilic flow channel, and
wetting gradient is formed in the flow channel .The microfluid self-driven paper base micro-fluidic chip has the advantages that operation is easy, the manufacturing cost is low, the flow channel with the
wetting gradient achieves self drive of microfluid, and the microfluid driving cost is greatly reduced .