293 results about "Hydrophilic hydrophobic" patented technology

This invention relates to porous polymeric materials having discrete regions that exhibit distinct surface properties. The invention also relates to methods of making such porous polymeric materials and their applications. The geography of the discrete regions can be determined in a selective and controlled manner. Porous materials having discrete regions of distinct hydrophilicity, hydrophobicity, oleophobicity, biological molecules binding capability, wetting and wicking property, presence or density of functional groups, chemical reactivity, electric charges, porosity and pore sizes can be manufactured using this invention.

The present invention relates to identifying protein epitopes and more particularly to a novel method for identifying, determining the location, optimal length of amino acid residues and immunobiological potency of protein epitopes by applying a custom negative cosine function fit algorithm to a protein hydropathy scale. This fit analysis is supplemented with experimental immunobiological data. The amino acid sequence of the protein epitopes of the present invention exhibit a hydrophobic-hydrophilic-hydrophobic hydropathy pattern of an approximately fixed length in a given protein.

A production method of a preparation containing drug-encapsulating polymer micelles is provided, which comprises dissolving a hydrophilic-hydrophobic block copolymer and a sparingly water-soluble drug in a volatile organic solvent, then removing the solvent, and stirring the residue with water at a temperature not higher than 30° C. to dissolve the drug-encapsulating polymer micelles into the water.

The present invention relates to identifying protein epitopes and more particularly to a novel method for identifying, determining the location, optimal length of amino acid residues and immunobiological potency of protein epitopes by fitting a hydrophilicity and/or hydrophobicity plot generated for the amino acid linear sequence of a polypeptide to a mathematically generated continuous curve thereby generating at least one set of potential epitopes which include ranked potential epitopes having a specific number of amino acid residues. The immunobiologically-active linear peptides are deemed the potential epitopes that exhibit the most alternating positioning about an equilibrium position when juxtaposed on the hydrophilicity and/or hydrophobicity plot and their optimal length corresponds to the specific number of amino acid residues in the set of ranked potential epitopes. The amino acid sequence of the protein epitopes of the present invention exhibit a hydrophobic-hydrophilic-hydrophobic motif

The invention provides a preparation method and equipment of a gradient wetted surface for achieving self-driving of liquid drops. The method comprises steps as follows: titanium dioxide particles are subjected to silanization treatment to obtain a super-hydrophobic coating; the coating coats a substrate in a spinning manner to obtain a super-hydrophobic surface; regioselective photolysis is carried out by deep ultraviolet light UV under the assist of a mask plate designed with a gradient light transmission area, and a gradient pattern designed on the mask plate can be copied on the surface of the super-hydrophobic coating; and an exposed area is transformed into super-hydrophilicity from super-hydrophobicity to obtain the gradient wetted surface. The equipment comprises the substrate and a hydrophilic-hydrophobic layer coating the surface of the substrate, wherein the hydrophilic-hydrophobic layer is divided into a plurality of areas. The preparation method and the equipment have the beneficial effects that customizing of the wetting gradient can be achieved by combining the gradient wetted surface prepared by hydrophilic-hydrophobic patterning; a microfluid can be self-driven on the surface in a directional manner; external auxiliary equipment is not needed; miniaturization and portability of a microfluidic system are easier to achieve; the preparation method is free of a strict requirement on a production environment and a substrate material; and the production cost is low.

The invention relates to a multifunctional graphene/high-molecular composite material water permeable membrane, a preparation method, and an application thereof. A high-molecular moisture-conductive polymer and a graphene-based composite material are organically bonded in a manner of forming effective chemical bonds, such as a hydrogen bond, an ionic bond, a covalent bond and the like, through polar functional groups, thereby forming a water permeation channel with reinforced hydrophilic-hydrophobic groups on the basis of the moisture-conductive polymer, and meanwhile, significantly improving the mechanical strength, anti-friction strength and acid- and alkali-resistant property, anti-bacterial and anti-fouling capabilities, heat conductivity and heat resistance and the like characters. The multifunctional composite water permeable membrane has long service life, is free of replacement during operation and has self-cleaning capability, and can be applied in the field of whole-heat exchanger, humidity conditioner, sewage treatment and other fields requiring water permeation or water filtration.

The invention belongs to the field of biochemistry analysis technology, and specifically relates to a one-step concentration and demineralization purification treatment method of biological samples by the use of patterning surface. The patterning surface can be widely applied in pretreatment and detection of biological samples. The method comprises the following steps of: constructing sealing patterning surface of hydrophobic-hydrophilic-hydrophobic region on substrate; dropping a polypeptide or protein solution onto the patterning surface prepared by the above step, naturally drying at room temperature to obtain dried sample points; dropping a substrate solution onto the above dried sample points, and naturally drying at room temperature and forming uniform cocrystallization of the sample and substrates on the patterning surface, so as to realize the concentration and demineralization purification treatment of biological samples. By the use of the patterning surface constructed in the invention, in MALDI-TOF MS detection, signal noise ratio, sensitivity and salt tolerance are significantly improved. The method has a great practical application value.

Design and preparation of a smart system, including a hydrophilic polymer nanoparticle as a core material and a hydrophilic-hydrophobic block copolymer as a coating nanolayer for use in a smart core-shell nanostructure flooding during enhanced oil recovery (EOR) process. The hydrophilic polymers are prepared by an inverse emulsion method. The central core of this nanostructure includes hydrophilic polymer. The nanolayer can be a surfmer. The binary properties of the shell and hydrophilic polymers increase the water viscosity in the water-oil interface and enhance oil recovery.

The invention discloses a microfluid self-driven paper base micro-fluidic chip and a preparation method and application thereof .The preparation method comprises the steps that titanium dioxide particles are subjected to silanization treatment to obtain super-hydrophobic coating liquid, filter paper is soaked in the coating liquid, natural drying is performed at room temperature, and due to the fact that super-hydrophobic nano particles are adsorbed to filter paper filter, a super-hydrophobic filter paper piece of a micro-nano composite structure is obtained; the geometric dimension of the micro-fluidic chip is designed on a mask plate, regional selective exposure is carried out on the micro-fluidic chip through deep ultraviolet light (UV) under the assistance of the mask plate, and therefore the designed pattern of the micro-fluidic chip is copied to the filter paper; the micro-fluidic chip comprises the filter paper and a hydrophilic-hydrophobic layer coating the surface layer of the filter layer; the hydrophilic-hydrophobic layer is provided with at least one hydrophilic flow channel, gradient-changing hydrophilic patterns are designed in the hydrophilic flow channel, and wetting gradient is formed in the flow channel .The microfluid self-driven paper base micro-fluidic chip has the advantages that operation is easy, the manufacturing cost is low, the flow channel with the wetting gradient achieves self drive of microfluid, and the microfluid driving cost is greatly reduced .

A composition for disinfecting a contact lens comprising an effective disinfecting amount of hydrogen peroxide and a surfactant comprising a copolymer of hydrophobe and hydrophile blocks the structure:<paragraph lvl="0"><in-line-formula>HO-(hydrophobe)x-(hydrophile)y-(hydrophobe)x-H</in-line-formula><paragraph lvl="0"><in-line-formula>or</in-line-formula><paragraph lvl="0"><in-line-formula>HO-(hydrophile)y-(hydrophobe)x-(hydrophile)y-H</in-line-formula>where x and y are integers reflecting the respective hydrophile and hydrophobe blocks of said copolymer; and the hydrophile component of the block copolymer constitutes less than 50 weight percent of the block copolymer. The block copolymer has a Ross-Miles foam height (ASTM designation D-1173-53; 0.1%, at 50° C.) of less than 1 mm.

The invention discloses a self-emulsifying doxorubicin nanometer medicament, which is prepared by connecting carbonyl of 8-hydroxyl acetyl on doxorubicin and hydrophilic groups by in-vivo degradable chemical bonds; and a precursor of the medicament introduces small molecular hydrophilic groups or hydrophilic polymer short chains into hydrophobic doxorubicin (DOX) molecules, so that the DOX molecules are hydrophilic-hydrophobic molecules. The self-emulsifying doxorubicin nanometer medicament can be subjected to self-assembly in water to form nanometer granules or nanometer vesicles, can target tumor tissues by utilizing the enhanced permeability and retention (EPR) effect, and has the characteristics of maintaining the high cytotoxicity of the doxorubicin, along with high medicament carrying capacity, and small toxic and side effects. The invention also discloses a preparation method for the self-emulsifying doxorubicin nanometer medicament which has high medicament carrying capacity and high yield and is suitable for industrial production.

Provided are a method for manufacturing a liquid drop self-driven microreactor and the microreactor manufactured through the method .The method comprises the steps that 1, super-hydrophobic titanium dioxide coating liquid is prepared; 2, a base body with a super-hydrophobic layer is prepared; 3, a mask plate is manufactured; 4, the microreactor is manufactured .The microreactor manufactured through the method comprises the base body and a hydrophilic-hydrophobic layer smeared to the surface of the base body .According to the hydrophilic-hydrophobic layer, three hydrophilic channels arranged in an inverted three square shape are designed on a hydrophobic coating, the two upper parallel hydrophilic channels on the upper portion are inlet channels of reaction reagents, and the volume ratio of the reaction reagents can be precisely controlled by controlling the distance between the two parallel channels .The two reaction reagents enter the third hydrophilic channel after being combined .The method for manufacturing the liquid drop self-driven microreactor and the microreactor manufactured through the method have the advantages that the problem that the precision of channels is insufficient is solved; self driving of microfluid is achieved, no external auxiliary equipment is needed, and microminiaturization, industrialization and portability of a system can be achieved more easily; the losses of the microfluid in the channels are small, and the efficiency of the microreactor is improved.

The invention relates to a method for controlling reversible transformation of hydrophilic-hydrophobic properties of folded surfaces by strain and an application. The method has the characteristics that a layer of 'hard' thin film is formed on the surface under a drawing state by carrying out drawing on a substrate made of flexible materials (flexible polymers such as PDMS (polydimethylsiloxane) and PI (polyimide)), homogeneous and ordered sinusoidal type folds are formed on the surface of the material by releasing drawing stress after the 'hard' thin film is formed, then the sinusoidal type folds are continuously drawn in a step-by-step manner, and contact angles are tested under different drawing lengths, so that the purpose of controlling the reversible transformation of the hydrophilic-hydrophobic properties of the surfaces is achieved. Folds with different periods and vibration amplitudes can be formed by changing the initial drawing length and the film plating thickness, and the control for the hydrophilic-hydrophobic properties in different ranges can be achieved. The method has the advantages of no toxicity and harm, simple operation, wide application range, good reversible property and the like.

The invention discloses a cyclic azobenzene amphiphilic segmented copolymer and its preparation method. The preparation method is concretely characterized in that the cyclic azobenzene amphiphilic segmented copolymer with controllable molecular weight, molecular weight distribution and ratio of a hydrophilic segment to a hydrophobic segment is obtained by combining through controllable atom transfer radical polymerization (ATRP) and an efficient CuAAC reaction. Compared with linear polymers having a same molecular weight, the cyclic polymer disclosed in the invention has the advantages of high Tg, fast photo-isomerization, sensitive light and pH response performances in an alkaline medium, and wide application potential in medicine release, surfactants, coatings, adhesives and separation films.

The invention provides a novel air cooling and dehumidifying apparatus on basis of hydrophilic/hydrophobic composite microporous membranes. The apparatus is used for controlling temperature and humidity in a spacecraft cabin under microgravity conditions. The apparatus employs a tube-and-shell structure. Low-temperature cold water flows through in numerous membrane tubes; to-be-treated humid air flows through the outsides of the membrane tubes; tube walls of the membrane tubes are hydrophilic-hydrophobic composite, wherein the inner wall of each membrane tube is hydrophobic so as to prevent low-temperature liquid in the tube from penetrating to the outside of the tube at a normal or relatively low pressure; while the outer wall of each membrane tube is hydrophilic, so as to effectively ensure that water vapor cooled on the surface of the outer wall of the membrane tube enters into micropores in the membrane smoothly and condensate water is transmitted unidirectionally from the outer wall of the membrane tube to the inner wall of the membrane tube. With continuous addition of enthalpy of the humid air, the temperature of the low-temperature cold water in the membrane tubes increases; temperature-increased cold water eliminates heat to cosmic space by radiation through a radiation radiator of the spacecraft, so that the temperature is reduced; the water becomes the low-temperature cold water again and can be used circularly by cooling and dehumidification. Water vapor of the humid air enters into cooling water in the tubes after condensation and can be reused.

Novel multiblock copolymers containing perfluorinated poly(arylene ether) as a hydrophobic segment and disulfonated poly(arylene ether sulfone) as a hydrophilic segment are provided. The multiblock copolymers are used to form proton exchange membranes that are thermally and hydrolytically stable, flexible, and that exhibit low methanol permeability and high proton conductivity. The proton exchange membranes are thus well-suited for use for use as polymer electrolytes in fuel cells.

A method for preparing powder rich in whey small peptides with molecular weight of 1000 daltons belongs to the technical field of processing dairy products. The main production process thereof is as follows: enzymatic hydrolysis, embedding and homogenization are firstly carried out on concentrated powder (WPC80 powder) containing 80 percent of whey protein, then the powder is prepared by spray drying, and the product can be used as functional ingredients for infant milk powder. The method adopts trypsin for enzymatic hydrolysis, the degree of hydrolysis achieves 20-21 percent, and then hydrophilic-hydrophobic wall materials of 5-10 percent of beta-cyclodextrin and 5-8 percent of lecithin are adopted, so the method can not only bury the bitterness, but also maintain the biological activities of anti-protein allergy and improve the immunity of the whey small peptides with the molecular weight of 1000 daltons to the maximum extent. The method can be applied to the infant formula milk powder and have good effects of improving the ability of anti-protein allergy of the infant milk powder and improving the immunity.

The invention discloses a material with a bionic hydrophobic-hydrophilic surface and a preparation method and application of the material. The material with the bionic hydrophobic-hydrophilic surfaceis a material with a micro-nano composite hydrophobic-hydrophilic surface which is formed by constructing nano protrusions on composite surfaces alternately existing between hydrophilic-hydrophobic regions with hydrophilic micrometer protrusions. The distribution density of the micrometer protrusions is 1,000/cm<2>-3,000/cm<2>.

The invention discloses a temperature-sensitive dispersing agent, a temperature-sensitive suspending liquid and application of temperature-sensitive dispersing agent and temperature-sensitive suspending liquid. The temperature-sensitive dispersing agent is a graft copolymer prepared by grafting a temperature-sensitive monomer on the homopolymerized main polymer chain of a dispersive monomer or a block polymer prepared by carrying out block copolymerization on the temperature-sensitive monomer and a dispersive monomer. The prepared temperature-sensitive dispersing agent has the hydrophilic-hydrophobic interconversion characteristic under the stimulation of different temperatures and can be prepared into the temperature-sensitive suspending liquid by being ground and dispersed with a power material; the prepared temperature-sensitive suspending liquid has good dispersity, the rheological property of the temperature-sensitive suspending liquid can be regulated and controlled by controlling temperature change, and the temperature-sensitive suspending liquid can be widely applied to the fields of ceramic wet forming, cement grouting, orifice well plugging of well drilling and the like.

The invention discloses a preparation method of a novel separation film, comprising the following steps of: respectively heating a starch cellulose film with water content of 5-30% and a protein film with water content of 5-30% to 100-150 DEG C and carrying out an expansion process to form a microporous hydrophilic film with micropores and a microporous hydrophobic film with the micropores, respectively. The microporous hydrophilic film and the microporous hydrophobic film are compounded to prepare a hydrophilic-hydrophobic, hydrophilic-hydrophobic-hydrophilic, hydrophobic-hydrophilic-hydrophobic composite film or the microporous hydrophilic film and the microporous hydrophobic film and a screen are compounded into an enhancing type separation film. The preparation method of the novel separation film has the advantages of favourable separation performance, low price, simple film-preparing process and low preparation cost.