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Antimicrobial composition with excellent biocompatibility

A biocompatibility and antimicrobial technology, which is applied in the field of antimicrobial compositions, can solve the problems of insufficient biocompatibility of antimicrobial compositions and unsatisfactory antimicrobial effects, so as to improve the antimicrobial effect, Improve the effect of inhibiting microorganisms, the effect of good biocompatibility

Inactive Publication Date: 2016-05-04
安徽律正科技信息服务有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The existing antimicrobial composition is not good enough in biocompatibility, and the antimicrobial effect is not ideal, so we propose an antimicrobial composition with excellent biocompatibility

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] An antimicrobial composition with excellent biocompatibility proposed by the present invention comprises the following raw materials in parts by weight: 30 parts of ethanol, 28 parts of ethylene glycol, 28 parts of propylene glycol, 20 parts of 6-aminopenicillanic acid, hydroxyl 20 parts of benzene, 10 parts of benzoic acid, 10 parts of propionic acid, 4 parts of nisin;

[0021] Its preparation method comprises the following steps:

[0022] S1, weighing ethanol, ethylene glycol, and propylene glycol according to the proportioning ratio, and mixing and reacting the above raw materials at a temperature of 30° C. for 1 hour to obtain a reactant A;

[0023] S2, weighing 6-aminopenicillanic acid, hydroxybenzene, benzoic acid, and propionic acid according to the weight ratio, putting the above-mentioned raw materials into the reactant A in sequence, and mixing them for 2 hours to obtain a mixture B;

[0024] S3, weighing nisin according to the proportion, adding nisin into m...

Embodiment 2

[0026] An antimicrobial composition with excellent biocompatibility proposed by the present invention comprises the following raw materials in parts by weight: 32 parts of ethanol, 29 parts of ethylene glycol, 29 parts of propylene glycol, 22 parts of 6-aminopenicillanic acid, hydroxyl 22 parts of benzene, 12 parts of benzoic acid, 12 parts of propionic acid, 4.5 parts of nisin;

[0027] Its preparation method comprises the following steps:

[0028] S1, weigh ethanol, ethylene glycol, and propylene glycol according to the proportioning ratio, and mix and react the above raw materials at a temperature of 32.5° C. for 1.25 hours to obtain reactant A;

[0029] S2, weighing 6-aminopenicillanic acid, hydroxybenzene, benzoic acid, and propionic acid according to the weight ratio, putting the above-mentioned raw materials into the reactant A in sequence, and mixing them for 2.25 hours to obtain a mixture B;

[0030] S3. Weighing nisin according to the proportioning ratio, adding nis...

Embodiment 3

[0032] An antimicrobial composition with excellent biocompatibility proposed by the present invention comprises the following raw materials in parts by weight: 34 parts of ethanol, 30 parts of ethylene glycol, 30 parts of propylene glycol, 24 parts of 6-aminopenicillanic acid, hydroxyl 24 parts of benzene, 14 parts of benzoic acid, 14 parts of propionic acid, 5 parts of nisin;

[0033] Its preparation method comprises the following steps:

[0034] S1, weighing ethanol, ethylene glycol, and propylene glycol according to the proportioning ratio, and mixing and reacting the above raw materials at a temperature of 35° C. for 1.5 hours to obtain reactant A;

[0035] S2, weighing 6-aminopenicillanic acid, hydroxybenzene, benzoic acid, and propionic acid according to the proportioning ratio, putting the above-mentioned raw materials into the reactant A in sequence, and mixing them for 2.5 hours to obtain a mixture B;

[0036] S3. Weighing nisin according to the weight ratio, adding ...

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PUM

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Abstract

The invention discloses an antimicrobial composition with excellent biocompatibility. The antimicrobial composition is prepared from, by weight, 30-38 parts of ethyl alcohol, 28-32 parts of ethylene glycol, 28-32 parts of propylene glycol, 20-28 parts of 6-aminopenicillanicacid, 20-28 parts of hydroxybenzene, 10-18 parts of benzoic acid, 10-18 parts of propionic acid and 4-6 parts of streptococcus lactis peptide. A preparation method of the antimicrobial composition comprises the steps that S1, ethyl alcohol, ethylene glycol and propylene glycol are weighed by ratio and subjected to a mixed reaction at the temperature of 30-40 DEG C for 1-2 hours to obtain a reactant A; S2, 6-aminopenicillanicacid, hydroxybenzene, benzoic acid and propionic acid are weighed by ratio, added into the reactant A in sequence and mixed with the reactant A for 2-3 hours to obtain a mixture B; S3, streptococcus lactis peptide is weighed by ratio and added into the mixture B three times. The preparation method is simple, and the prepared antimicrobial composition is good in biocompatibility and suitable for popularization.

Description

technical field [0001] The invention relates to the technical field of antimicrobial compositions, in particular to an antimicrobial composition with excellent biocompatibility. Background technique [0002] Microorganisms are a large group of organisms including bacteria, viruses, fungi, and some small protozoa. Individuals are tiny and closely related to human life. Widely involved in health, medicine, industry and agriculture, environmental protection and many other fields. In textbooks in mainland China, microorganisms are divided into the following eight categories: bacteria, viruses, fungi, actinomycetes, rickettsia, mycoplasma, chlamydia, and spirochetes. [0003] The existing antimicrobial composition is not good enough in biocompatibility, and the antimicrobial effect is not ideal, so we propose an antimicrobial composition with excellent biocompatibility. Contents of the invention [0004] Based on the technical problems existing in the background technology, t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N63/02A01N43/90A01N31/08A01N37/10A01N37/02A01P1/00
CPCA01N31/08A01N37/02A01N37/10A01N43/90A01N63/10A01N2300/00
Inventor 吴兴伟
Owner 安徽律正科技信息服务有限公司