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Medicine for treating asthma

A technology for drugs and asthma, applied in the field of medicine, can solve the problems of difficulty in guaranteeing the quality of drugs and inconvenience in industrialized production of drugs, etc., and achieve the effects of reducing airway hyperresponsiveness, relieving bronchial spasm, and treating pulmonary inflammation.

Pending Publication Date: 2016-06-01
程潜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since there are thirteen Chinese herbal medicines in this formula, and there are too many kinds of Chinese herbal medicines, it is still unknown which Chinese herbal medicines play the main role in it. Therefore, it is difficult to guarantee the quality of the medicine, and it is not convenient for industrial production of the medicine

Method used

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  • Medicine for treating asthma
  • Medicine for treating asthma
  • Medicine for treating asthma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1 A kind of medicine for the treatment of asthma

[0031] The drug is marine algae glycoprotein;

[0032] Said marine algae glycoprotein, in parts by weight, includes sugar 1%, protein 99%,

[0033] The molecular weight is 0.2kDa;

[0034] The marine algae are: cyanobacteria;

[0035] The sugar is a polysaccharide;

[0036] The polysaccharides include: xylose, fucose, arabinose, glucose, galactose, mannose, rhamnose;

[0037] The protein includes: asparagine, cysteine, lysine, arginine, serine, threonine;

Embodiment 2

[0038] Embodiment 2 A kind of medicine for the treatment of asthma

[0039] The drug is marine algae glycoprotein;

[0040] Said marine algae glycoprotein, in parts by weight, comprises sugar 25%, protein 75%,

[0041] The molecular weight is 55kDa;

[0042] The marine algae is: green algae;

[0043] The sugar is a polysaccharide;

[0044] The polysaccharides include: xylose, fucose, arabinose, glucose, galactose, mannose, rhamnose;

[0045] The protein includes: asparagine, cysteine, lysine, arginine, serine, threonine.

Embodiment 3

[0046] Embodiment 3 A kind of medicine for the treatment of asthma

[0047] The drug is marine algae glycoprotein;

[0048] Said marine algae glycoprotein, in parts by weight, comprises sugar 41%, protein 59%,

[0049] The molecular weight is 3kDa;

[0050] The marine algae are: cyanobacteria;

[0051] The sugar is a polysaccharide;

[0052] The polysaccharides include: xylose, fucose, arabinose, glucose, galactose, mannose, rhamnose;

[0053] The protein includes: asparagine, cysteine, lysine, arginine, serine, threonine.

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Abstract

The invention provides medicine for treating asthma. The medicine is glycoprotein, mixture of polysaccharide and protein, polypeptide or protein. The medicine has the advantages that the bronchial hyperresponsiveness of a mouse asthma model can be effectively lowered, the tracheospasm can be relieved, and airway pressure-time index (APTI) is 726-880 per second centimeter water column; the inflammation in the lung can be treated effectively, inflammatory cell infiltration can be reduced, and the percentage of eosinophilic granulocyte is 14.6-16.6%; the gamma-interferon (IFN-gamma) and antibody which are capable of inhibiting asthmatic attack can be increased, and the contents of interleukin-4 (IL-4), interleukin-5 (IL-5) and interleukin-13 (IL-13) which can induce the asthma can be lowered; the medicine is safe, efficient, free of side effect, quick in action during asthma preventing and treatment, capable of relieving chest distress and short of breath and evident in curative effect on the asthma.

Description

technical field [0001] The invention relates to a medicine for treating asthma and belongs to the technical field of medicine. Background technique [0002] Asthma is a common disease of the respiratory tract, which refers to chronic airway inflammation involving a variety of degenerated cells, such as eosinophils, mast cells, T cells, airway epithelial cells, and cell components. The clinical manifestations of asthma patients are paroxysmal wheezing, shortness of breath, chest tightness or coughing and other symptoms. A small number of patients may also have chest pain as the main manifestation. The disease has a high incidence worldwide. There are about 300 million asthma patients worldwide. About 30 million patients. The disease is prone to recurrent attacks, which can lead to complications such as chronic obstructive pulmonary disease, emphysema, pulmonary heart disease, heart failure, respiratory failure, etc., seriously endangering people's health, weakening labor abi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/16A61K33/32A61K31/7012A61K31/715A61P11/06A61K36/02
CPCA61K31/7012A61K31/715A61K36/02A61K38/14A61K38/16A61K33/32A61K36/195A61K36/31A61K36/315A61K36/535A61K36/704A61K2300/00
Inventor 程潜徐宝贞程龙
Owner 程潜