Magnetic suction membrane enrichment and separation device and its application method in solid-phase spectroscopic detection

Abstract

The invention discloses a magnetic membrane enrichment and separation device. The device comprises upper and lower pressing pieces, a membrane material and upper and lower magnetic materials, wherein solution input channels and the upper magnetic material are arranged on the upper pressing piece, the upper pressing piece is a solution input end, filtrate outflow channels and the lower magnetic material are arranged on the lower pressing piece, and the lower pressing piece is a filtrate outflow end; the membrane material is arranged between the upper pressing piece and the lower pressing piece, the upper pressing piece and the lower pressing piece press the membrane material tightly through a magnetic force, and solutions are separated and enriched on the membrane material through the solution input channels, and flow out through the filtrate outflow channels. The membrane material can be removed after membrane enrichment and separation are carried out, and the subsequent solid phase spectrum detection can be directly performed without eluting the membrane material. According to the invention, the force is applied to the membrane material uniformly for the magnetic force, and then the membrane material is not easily damaged, so as to be beneficial to the spectrum measurement on a membrane; the upper pressing piece and the lower pressing piece are pressed and separated easily and conveniently; measured substances can be separated and enriched uniformly, so as to facilitate good spectral reproducibility of measuring points on the membrane; hypothetically, a multi-channel membrane enrichment technology is relatively suitable for quantitative analysis.

Description

technical field [0001] The invention relates to the technical field of sample pretreatment and spectral analysis in analytical chemistry, in particular, a simple magnetic suction membrane enrichment and separation device and its application method in solid-phase spectral detection. Background technique [0002] In the field of analytical chemistry technology, the membrane separation process is a method of separating mixtures using thin films, which is mainly a sieving separation process using fluid pressure difference as the driving force. Since the membrane has selective permeability (filterability) to different substances, it can retain certain substances, so it can realize the screening and separation of different substances or components. Membrane enrichment technology is a solid-phase extraction technology based on membrane filtration process. It uses the physical and chemical interactions between the analyte in the solution and the membrane to enrich the analyte on the...

AI Technical Summary

Problems solved by technology

[0003] The conventional membrane enrichment and separation device uses a long handle clip with a spring to connect and fix the sample input end, membrane and filtrate output end. The disadvantage is that the tightness of the connection between the input end and the output end will be uncertain. , the force close to the spring is large, and the force far away from the spring is small, which directly affects the uniformity of the membrane material connection, resulting in uneven enrichment of samples at different positions on the membrane, and affecting the accuracy of solid-phase spectroscopic analysis.

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