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Composite nano-zinc oxide additive and preparation method and application thereof

A nano-zinc oxide and additive technology, applied in the field of feed additives, can solve the problems of unstable utilization effect and low bioavailability of nano-zinc oxide, and achieve the effect of maintaining intestinal health, preventing piglet diarrhea, and stable effect

Active Publication Date: 2016-08-31
德阳定芯丸生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the problems of low bioavailability and unstable utilization effect of nano-zinc oxide, the purpose of the present invention is to provide a composite nano-zinc oxide additive and its preparation method and use

Method used

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  • Composite nano-zinc oxide additive and preparation method and application thereof
  • Composite nano-zinc oxide additive and preparation method and application thereof
  • Composite nano-zinc oxide additive and preparation method and application thereof

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preparation example Construction

[0032] The invention provides a composite nano-zinc oxide additive as well as its preparation method and application. The composite nano-zinc oxide additive comprises the following components: 70-80% of nano-zinc oxide, 5-15% of plant essential oil and 2-10% of oligosaccharide in weight percentage.

[0033] Wherein, in the above composite nano-zinc oxide additive, the plant essential oil is at least one of oregano oil, cinnamon essential oil or garlic essential oil, preferably oregano oil.

[0034] Wherein, in the above composite nano-zinc oxide additive, the oligosaccharide is at least one of fructo-oligosaccharide, chitosan-oligosaccharide or xylo-oligosaccharide, preferably fructo-oligosaccharide.

[0035] Wherein, the above-mentioned composite nano-zinc oxide additive also includes 9.05-14.15 wt% of binder.

[0036] Wherein, in the above-mentioned composite nano-zinc oxide additive, the binder is composed of xanthan gum, cellulose and bentonite, the weight ratio of xantha...

Embodiment 1

[0059] a. Add water to the binding agent (0.15% xanthan gum, 3% carboxymethyl cellulose, 5% microcrystalline cellulose and 2.85% bentonite) to make 0.1g / ml aqueous solution, then add 15% garlic essential oil, stir to mix well;

[0060] B, after mixing 72% nano-zinc oxide and 2% xylo-oligosaccharide, add in the mixed liquor that step a gains, stir to obtain composite nano-zinc oxide additive soft material;

[0061] c. Add the soft material prepared in step b into a granulator to granulate, then polish it through a shot blasting machine, dry it in a dryer, add a grading sieve, and sieve it to obtain a composite nano-zinc oxide additive of 20 to 40 mesh 1 .

Embodiment 2

[0063] a, binder (0.05% xanthan gum, 4% hypromellose, 5% microcrystalline cellulose and 3.95% bentonite) is made into 0.12g / ml aqueous solution, and 8% oregano oil is added , stir and mix evenly;

[0064] B, after mixing 75% nanometer zinc oxide and 4% fructooligosaccharide, add in the mixed solution of step a gained, stir to obtain composite nanometer zinc oxide additive soft material;

[0065] c. Add the soft material prepared in step b into a granulator to granulate, then polish it with a shot blasting machine, dry it with a dryer, add a grading sieve, and sieve it to obtain a composite nano-zinc oxide additive of 20 to 40 mesh 2 .

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Abstract

The invention belongs to the field of feed additives and specifically relates to a composite nano-zinc oxide additive and its preparation method and application. In allusion to problems such as low bioavailability and instable using effect of nano-zinc oxide, the invention provides a composite nano-zinc oxide additive and its preparation method and application. The composite nano-zinc oxide additive comprises the following ingredients (by weight): 70-80% of nano-zinc oxide, 5-15% of plant essential oil and 2-10% of oligosaccharide. By cooperation of plant essential oil and oligosaccharide and nao-zinc oxide, the anti-diarrhea effect of naon-zinc oxide is enhanced through compatibility of other synergistic substances on one hand; and on the other hand, damage of gastric acid to nano-zinc oxide passing through stomach is reduced such that effective dose of nano-zinc oxide which succeeds in reaching the intestinal tract is increased so as to enhance the anti-diarrhea effect of piglets.

Description

technical field [0001] The invention belongs to the field of feed additives, and in particular relates to a composite nanometer zinc oxide additive and its preparation method and application. Background technique [0002] Piglet diarrhea due to early weaning stress is a very serious problem in today's intensive pig industry. According to relevant statistical data, the mortality rate caused by weaning stress diarrhea reaches 11%, and it is estimated that 10 million piglets in the world die each year, which brings huge economic losses to the pig industry. In recent years, many scholars at home and abroad have shown that adding high doses of zinc oxide to the diet of weaned piglets can effectively reduce the rate of diarrhea and promote the growth of piglets. However, due to the low bioavailability of zinc oxide, the weaned piglets are about 5% to 10%, most of which are excreted from the feces and are not used, and cause serious pollution to the environment. [0003] Nano-zin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K50/30A23K50/60A23K20/158A23K20/163A23K20/20A23K40/10
Inventor 申俊华李小兵张滴
Owner 德阳定芯丸生物科技有限公司
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